Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Daniel D Pinschewer"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010489 (2022)
Vertical transmission of Bartonella infection has been reported for several mammalian species including mice and humans. Accordingly, it is commonly held that acquired immunological tolerance contributes critically to the high prevalence of Bartonell
Externí odkaz:
https://doaj.org/article/f145a067a18d4b3789787e585b3a94cc
Publikováno v:
eLife, Vol 10 (2021)
A hallmark of adaptive immunity is CD4 T cells’ ability to differentiate into specialized effectors. A long-standing question is whether T cell receptor (TCR) signal strength can dominantly instruct the development of Th1 and T follicular helper (T
Externí odkaz:
https://doaj.org/article/fab26f24ed194989915652fbcd6a54bf
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.
Autor:
Kseniya Khamina, Alexander Lercher, Michael Caldera, Christopher Schliehe, Bojan Vilagos, Mehmet Sahin, Lindsay Kosack, Anannya Bhattacharya, Peter Májek, Alexey Stukalov, Roberto Sacco, Leo C James, Daniel D Pinschewer, Keiryn L Bennett, Jörg Menche, Andreas Bergthaler
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006758 (2017)
RNA-dependent RNA polymerases (RdRps) play a key role in the life cycle of RNA viruses and impact their immunobiology. The arenavirus lymphocytic choriomeningitis virus (LCMV) strain Clone 13 provides a benchmark model for studying chronic infection.
Externí odkaz:
https://doaj.org/article/61f6526a55ef46658467aab0a567e0fd
Autor:
Rami Sommerstein, Lukas Flatz, Melissa M Remy, Pauline Malinge, Giovanni Magistrelli, Nicolas Fischer, Mehmet Sahin, Andreas Bergthaler, Sebastien Igonet, Jan Ter Meulen, Dorothée Rigo, Paolo Meda, Nadia Rabah, Bruno Coutard, Thomas A Bowden, Paul-Henri Lambert, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005276 (2015)
Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection a
Externí odkaz:
https://doaj.org/article/88adfa2938774026b7ab7e3f585a6933
Autor:
Elodie Belnoue, Paola Fontannaz, Anne-Françoise Rochat, Chantal Tougne, Andreas Bergthaler, Paul-Henri Lambert, Daniel D Pinschewer, Claire-Anne Siegrist
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85302 (2013)
Infant mortality from viral infection remains a major global health concern: viruses causing acute infections in immunologically mature hosts often follow a more severe course in early life, with prolonged or persistent viral replication. Similarly,
Externí odkaz:
https://doaj.org/article/7e2c1e8b65d647c3abe52c2d8c51b1c4
Autor:
Margarete Arras, Daniel L Glauser, Paulin Jirkof, Andreas Rettich, Benjamin Schade, Paolo Cinelli, Daniel D Pinschewer, Mathias Ackermann
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29726 (2012)
Refined vaccines and adjuvants are urgently needed to advance immunization against global infectious challenges such as HIV, hepatitis C, tuberculosis and malaria. Large-scale screening efforts are ongoing to identify adjuvants with improved efficacy
Externí odkaz:
https://doaj.org/article/00a5b32e0e794d43ad96b8e5939a4141
Autor:
Lukas Flatz, Toni Rieger, Doron Merkler, Andreas Bergthaler, Tommy Regen, Mariann Schedensack, Lukas Bestmann, Admar Verschoor, Mario Kreutzfeldt, Wolfgang Brück, Uwe-Karsten Hanisch, Stephan Günther, Daniel D Pinschewer
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000836 (2010)
Lassa virus (LASV), the causative agent of Lassa fever (LF), is endemic in West Africa, accounting for substantial morbidity and mortality. In spite of ongoing research efforts, LF pathogenesis and mechanisms of LASV immune control remain poorly unde
Externí odkaz:
https://doaj.org/article/1fd1372c1c1d49f0804b35f627226502
Autor:
Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J. Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Biology, Vol 7, Iss 8 (2009)
Externí odkaz:
https://doaj.org/article/ec0219d9772549e08bac957492e2f23a
Autor:
Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Biology, Vol 7, Iss 4, p e1000080 (2009)
CD8 T cells are recognized key players in control of persistent virus infections, but increasing evidence suggests that assistance from other immune mediators is also needed. Here, we investigated whether specific antibody responses contribute to con
Externí odkaz:
https://doaj.org/article/8a27a9e5804d4df3b1f7cdd8b9062da4
Autor:
Andreas Bergthaler, Nicolas U Gerber, Doron Merkler, Edit Horvath, Juan Carlos de la Torre, Daniel D Pinschewer
Publikováno v:
PLoS Pathogens, Vol 2, Iss 6, p e51 (2006)
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical infr
Externí odkaz:
https://doaj.org/article/d26c52142d3a4b29aa286e6c4a02411d