Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Daniel D Billadeau"'
Autor:
Cristina Correia, Taylor M Weiskittel, Choong Yong Ung, Jose C Villasboas Bisneto, Daniel D Billadeau, Scott H Kaufmann, Hu Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cancer stem cells (CSCs) represent a small fraction of the total cancer cell population, yet they are thought to drive disease propagation, therapy resistance and relapse. Like healthy stem cells, CSCs possess the ability to self-renew and differenti
Externí odkaz:
https://doaj.org/article/ad26659fb5b846ef94487865a5a290c1
Autor:
Sai Srinivas Panapakkam Giridharan, Guangming Luo, Pilar Rivero-Rios, Noah Steinfeld, Helene Tronchere, Amika Singla, Ezra Burstein, Daniel D Billadeau, Michael A Sutton, Lois S Weisman
Publikováno v:
eLife, Vol 11 (2022)
Cell surface receptors control how cells respond to their environment. Many cell surface receptors recycle from endosomes to the plasma membrane via a recently discovered pathway, which includes sorting-nexin SNX17, Retriever, WASH, and CCC complexes
Externí odkaz:
https://doaj.org/article/7c35c8cb7b114934a237748c8f78a216
Autor:
Dingdong Liu, Fan Yang, Zhe Liu, Jinrui Wang, Wenjie Huang, Wentong Meng, Daniel D Billadeau, Qingxiang Sun, Xianming Mo, Da Jia
Publikováno v:
PLoS Biology, Vol 18, Iss 5, p e3000746 (2020)
Members of the Tre2-Bub2-Cdc16 (TBC) family often function to regulate membrane trafficking and to control signaling transductions pathways. As a member of the TBC family, TBC1D23 is critical for endosome-to-Golgi cargo trafficking by serving as a br
Externí odkaz:
https://doaj.org/article/0475526ffd964b1e9c3a9915adacdb4d
Autor:
Xin Yong, Lin Zhao, Wankun Deng, Hongbin Sun, Xue Zhou, Lejiao Mao, Wenfeng Hu, Xiaofei Shen, Qingxiang Sun, Daniel D Billadeau, Yu Xue, Da Jia
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000631 (2020)
Endocytic recycling of internalized transmembrane proteins is essential for many important physiological processes. Recent studies have revealed that retromer-related Sorting Nexin family (SNX)-Bin/Amphiphysin/Rvs (BAR) proteins can directly recogniz
Externí odkaz:
https://doaj.org/article/5cd674d62f9c46ac913fb8b71c286923
Autor:
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O. Watzlawik, Yin Maggie Chen, Ariel L. Raybuck, Daniel D. Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark R. Boothby, Hu Zeng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Germinal center (GC) formation, which is an integrant part of humoral immunity, involves energy-consuming metabolic reprogramming. Rag-GTPases are known to signal amino acid availability to cellular pathways that regulate nutrient distributi
Externí odkaz:
https://doaj.org/article/b9a0aef0153c41448af1034c22be9cab
Autor:
Zehua Shang, Sitao Zhang, Jinrui Wang, Lili Zhou, Xinyue Zhang, Daniel D. Billadeau, Peiguo Yang, Lingqiang Zhang, Fangfang Zhou, Peng Bai, Da Jia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Stress granules (SGs) are induced by various environmental stressors, resulting in their compositional and functional heterogeneity. SGs play a crucial role in the antiviral process, owing to their potent translational repressive effects and
Externí odkaz:
https://doaj.org/article/2a58307d4cc34ed0be0b78ff8fafa5ff
Autor:
Daniel B Graham, Douglas G Osborne, Joshua T Piotrowski, Timothy S Gomez, Grzegorz B Gmyrek, Holly M Akilesh, Adish Dani, Daniel D Billadeau, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98606 (2014)
Immature dendritic cells (DCs) maintain a highly dynamic pool of recycling MHCII that promotes sampling of environmental antigens for presentation to T helper cells. However, the molecular basis of MHCII recycling and the cellular machinery that orch
Externí odkaz:
https://doaj.org/article/a6cc93bbe2e340b4906972cb86aba80c
Autor:
Joanna Kim, Michael J Shapiro, Adebowale O Bamidele, Pinar Gurel, Puspa Thapa, Henry N Higgs, Karen E Hedin, Virginia S Shapiro, Daniel D Billadeau
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85090 (2014)
Actin depolymerizing factor-homology (ADF-H) family proteins regulate actin filament dynamics at multiple cellular locations. Herein, we have investigated the function of the ADF-H family member coactosin-like 1 (COTL1) in the regulation of actin dyn
Externí odkaz:
https://doaj.org/article/aa4b7635dda546b7946f964eb2927511
Autor:
Ana V Miletic, Daniel B Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6599 (2009)
BACKGROUND:T cell receptor (TCR) engagement leads to formation of signaling microclusters and induction of rapid and dynamic changes in the actin cytoskeleton, although the exact mechanism by which the TCR initiates actin polymerization is incomplete
Externí odkaz:
https://doaj.org/article/531bd18f9d744b3db2490e47f9786ecb
Autor:
Daheui Choi, Alan M. Gonzalez‐Suarez, Mihai G. Dumbrava, Michael Medlyn, Jose M. deHoyos‐Vega, Frank Cichocki, Jeffrey S. Miller, Li Ding, Mojun Zhu, Gulnaz Stybayeva, Alexandre Gaspar‐Maia, Daniel D. Billadeau, Wen Wee Ma, Alexander Revzin
Publikováno v:
Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)
Abstract Patient‐derived cancer organoids (PDOs) hold considerable promise for personalizing therapy selection and improving patient outcomes. However, it is challenging to generate PDOs in sufficient numbers to test therapies in standard culture p
Externí odkaz:
https://doaj.org/article/8bace5ec4db746318ee3c8614e155c51