Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Daniel D Bikle"'
Autor:
Daniel D Bikle
Publikováno v:
JBMR Plus, Vol 5, Iss 1, Pp n/a-n/a (2021)
ABSTRACT The free hormone hypothesis postulates that only the nonbound fraction (the free fraction) of hormones that otherwise circulate in blood bound to their carrier proteins is able to enter cells and exert biologic effects. In this review, I wil
Externí odkaz:
https://doaj.org/article/0fb2e20c035e45c0b84cb9c0322b26e2
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238076 (2020)
Epidermal lineages and injury induced regeneration are controlled by transcriptional programs coordinating cellular signaling and epigenetic regulators, but the mechanism remains unclear. Previous studies showed that conditional deletion of the trans
Externí odkaz:
https://doaj.org/article/e74ec2585ffd45a88f6708e5b69d2df7
Autor:
Keigo Yoshizaki, Lizhi Hu, Thai Nguyen, Kiyoshi Sakai, Bing He, Chak Fong, Yoshihiko Yamada, Daniel D Bikle, Yuko Oda
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99991 (2014)
Cell fates are determined by specific transcriptional programs. Here we provide evidence that the transcriptional coactivator, Mediator 1 (Med1), is essential for the cell fate determination of ectodermal epithelia. Conditional deletion of Med1 in vi
Externí odkaz:
https://doaj.org/article/882e07fcf4724437a5f5a08746356377
Autor:
Roman Thaler, Keigo Yoshizaki, Thai Nguyen, Satoshi Fukumoto, Pamela Den Besten, Daniel D. Bikle, Yuko Oda
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Postnatal cell fate is postulated to be primarily determined by the local tissue microenvironment. Here, we find that Mediator 1 (Med1) dependent epigenetic mechanisms dictate tissue-specific lineage commitment and progression of dental epit
Externí odkaz:
https://doaj.org/article/5754eb11d520481e8318a5cc8e6882d2
Autor:
Andrea Giustina, Luigi di Filippo, Agnese Allora, Daniel D. Bikle, Giulia Martina Cavestro, David Feldman, Giovanni Latella, Salvatore Minisola, Nicola Napoli, Silvia Trasciatti, Melin Uygur, John P. Bilezikian
Publikováno v:
Reviews in Endocrine and Metabolic Disorders. 24:121-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc55de2854beca6550a35cbad9a9df3
https://doi.org/10.1007/s11154-023-09792-7
https://doi.org/10.1007/s11154-023-09792-7
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/6e7246cda6aa4f6cb8657b35b304d1b1
Autor:
Daniel D, Bikle
Publikováno v:
Reviews in Endocrine & Metabolic Disorders
Covid-19 has to date infected a confirmed 275 million people with 5.4 million, now dead, with the count rising every day. Although the virus, SARS-CoV2, causing Covid-19 infects many cells in the body, its infection of the upper and lower respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897488de53af0f281e2c753223caca1a
https://doi.org/10.1007/s11154-021-09707-4
https://doi.org/10.1007/s11154-021-09707-4
Publikováno v:
J Invest Dermatol
The Ca(2+)-sensing receptor (CaSR) drives essential Ca(2+) and E-cadherin-mediated processes in the epidermis, including differentiation (Komuves et al., 2002), cell-to-cell adhesion (Tu et al., 2008) and epidermal barrier homeostasis in cells and yo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915bcb25bc12cf1921b5fcc0c66b74fd
https://doi.org/10.1016/j.jid.2021.03.025
https://doi.org/10.1016/j.jid.2021.03.025
Publikováno v:
Osteoporosis International. 32:2587-2592
Hypercalcemia occurs in up to 30% of patients with malignancies and can be due to osteolysis by metastases, parathyroid hormone-related protein (PTHrP), excess 1,25-dihydroxyvitamin D (1,25(OH)2D) production or, rarely, ectopic parathyroid hormone (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b04232039a04a394d6a01e55c406cb
https://doi.org/10.1007/s00198-021-06054-7
https://doi.org/10.1007/s00198-021-06054-7
Autor:
Roman Thaler, Keigo Yoshizaki, Thai Nguyen, Satoshi Fukumoto, Pamela Den Besten, Daniel D. Bikle, Yuko Oda
Postnatal cell fate has been postulated to be primarily determined by the local tissue microenvironment. Here, we found that Mediator 1 (Med1) dependent epigenetic mechanisms dictate tissue-specific lineage commitment and progression of dental epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a16c970dfb5ef184c0761680166b412
https://doi.org/10.1101/2022.09.08.507153
https://doi.org/10.1101/2022.09.08.507153
