Biomarker discovery by sparse canonical correlation analysis of complex clinical phenotypes of tuberculosis and malaria.

Autor: Juho Rousu, Daniel D Agranoff, Olugbemiro Sodeinde, John Shawe-Taylor, Delmiro Fernandez-Reyes

Publikováno v: PLoS Computational Biology, Vol 9, Iss 4, p e1003018 (2013)

Biomarker discovery aims to find small subsets of relevant variables in 'omics data that correlate with the clinical syndromes of interest. Despite the fact that clinical phenotypes are usually characterized by a complex set of clinical parameters, c

Externí odkaz: https://doaj.org/article/42067096a47a47b3a0176c65567bf3f0

Discriminating active from latent tuberculosis in patients presenting to community clinics

Autor: Dimitrios Athanasakis, Daniel D. Agranoff, Rosario Montoya, Francesca Battaglia, Carlton A. Evans, Delmiro Fernandez-Reyes, Teresa Valencia, Gurjinder Sandhu, Barry K. Ely, Robert H. Gilman, Jon S. Friedland

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e38080 (2012)

BACKGROUND\ud \ud Because of the high global prevalence of latent TB infection (LTBI), a key challenge in endemic settings is distinguishing patients with active TB from patients with overlapping clinical symptoms without active TB but with co-existi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ef5d20d1c72e3763356f9d4046f49e
https://pubmed.ncbi.nlm.nih.gov/22666453

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences.

Autor: Lee JY; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Wing PAC; Nuffield Department of Medicine, The University of Oxford, Oxford, United Kingdom.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), The University of Oxford, Oxford, United Kingdom., Gala DS; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Noerenberg M; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom.; MRC-University of Glasgow Centre for Virus Research, The University of Glasgow, Glasgow, United Kingdom., Järvelin AI; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Titlow J; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Zhuang X; Nuffield Department of Medicine, The University of Oxford, Oxford, United Kingdom., Palmalux N; MRC-University of Glasgow Centre for Virus Research, The University of Glasgow, Glasgow, United Kingdom., Iselin L; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Thompson MK; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Parton RM; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom., Prange-Barczynska M; Nuffield Department of Medicine, The University of Oxford, Oxford, United Kingdom.; Ludwig Institute for Cancer Research, The University of Oxford, Oxford, United Kingdom., Wainman A; Sir William Dunn School of Pathology, The University of Oxford, Oxford, United Kingdom., Salguero FJ; UK Health Security Agency, UKHSA-Porton Down, Salisbury, United Kingdom., Bishop T; Nuffield Department of Medicine, The University of Oxford, Oxford, United Kingdom.; Ludwig Institute for Cancer Research, The University of Oxford, Oxford, United Kingdom., Agranoff D; Department of Infectious Diseases, University Hospitals Sussex NHS Foundation Trust, Brighton, United Kingdom., James W; Sir William Dunn School of Pathology, The University of Oxford, Oxford, United Kingdom.; James & Lillian Martin Centre, Sir William Dunn School of Pathology, The University of Oxford, Oxford, United Kingdom., Castello A; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom.; MRC-University of Glasgow Centre for Virus Research, The University of Glasgow, Glasgow, United Kingdom., McKeating JA; Nuffield Department of Medicine, The University of Oxford, Oxford, United Kingdom.; Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), The University of Oxford, Oxford, United Kingdom., Davis I; Department of Biochemistry, The University of Oxford, Oxford, United Kingdom.

Publikováno v: ELife [Elife] 2022 Jan 20; Vol. 11. Date of Electronic Publication: 2022 Jan 20.

An ageing population and changing UK bacteraemia profile may affect the characteristics and microbiology of infective spondylodiscitis.

Autor: Donovan J; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK. Electronic address: josephdonovan@doctors.org.uk., Skittrall JP; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK., Moore T; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK., Sargent C; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK., Agranoff D; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK., Llewelyn M; Department of Infectious Diseases, Royal Sussex County Hospital, Eastern Road, Brighton, BN2 5BE, UK.

Publikováno v: The Journal of infection [J Infect] 2016 Jul; Vol. 73 (1), pp. 91-3. Date of Electronic Publication: 2016 Apr 09.

Guillain-Barre syndrome as a paraneoplastic manifestation of disseminated squamous cell carcinoma.

Autor: Navani V; Department of Infectious Diseases, Brighton and Sussex University Hospitals, Brighton, UK. vishalnavani@googlemail.com, Webster D, Williams SK, Agranoff D

Publikováno v: BMJ case reports [BMJ Case Rep] 2013 May 31; Vol. 2013. Date of Electronic Publication: 2013 May 31.