Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Daniel D, Bikle"'
Autor:
Roman Thaler, Keigo Yoshizaki, Thai Nguyen, Satoshi Fukumoto, Pamela Den Besten, Daniel D. Bikle, Yuko Oda
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Postnatal cell fate is postulated to be primarily determined by the local tissue microenvironment. Here, we find that Mediator 1 (Med1) dependent epigenetic mechanisms dictate tissue-specific lineage commitment and progression of dental epit
Externí odkaz:
https://doaj.org/article/5754eb11d520481e8318a5cc8e6882d2
Autor:
Daniel D. Bikle
Publikováno v:
JBMR Plus, Vol 5, Iss 12, Pp n/a-n/a (2021)
ABSTRACT Our predominant understanding of the actions of vitamin D involve binding of its ligand, 1,25(OH)D, to the vitamin D receptor (VDR), which for its genomic actions binds to discrete regions of its target genes called vitamin D response elemen
Externí odkaz:
https://doaj.org/article/49bf944eb4c04e3285e6e9b3d59631db
Autor:
Daniel D Bikle
Publikováno v:
JBMR Plus, Vol 5, Iss 1, Pp n/a-n/a (2021)
ABSTRACT The free hormone hypothesis postulates that only the nonbound fraction (the free fraction) of hormones that otherwise circulate in blood bound to their carrier proteins is able to enter cells and exert biologic effects. In this review, I wil
Externí odkaz:
https://doaj.org/article/0fb2e20c035e45c0b84cb9c0322b26e2
Autor:
Andrea Giustina, Luigi di Filippo, Agnese Allora, Daniel D. Bikle, Giulia Martina Cavestro, David Feldman, Giovanni Latella, Salvatore Minisola, Nicola Napoli, Silvia Trasciatti, Melin Uygur, John P. Bilezikian
Publikováno v:
Reviews in Endocrine and Metabolic Disorders. 24:121-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc55de2854beca6550a35cbad9a9df3
https://doi.org/10.1007/s11154-023-09792-7
https://doi.org/10.1007/s11154-023-09792-7
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/6e7246cda6aa4f6cb8657b35b304d1b1
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238076 (2020)
Epidermal lineages and injury induced regeneration are controlled by transcriptional programs coordinating cellular signaling and epigenetic regulators, but the mechanism remains unclear. Previous studies showed that conditional deletion of the trans
Externí odkaz:
https://doaj.org/article/e74ec2585ffd45a88f6708e5b69d2df7
Publikováno v:
Bone Reports, Vol 8, Iss , Pp 255-267 (2018)
Although the kidney was initially thought to be the sole organ responsible for the production of 1,25(OH)2D via the enzyme CYP27b1, it is now appreciated that the expression of CYP27b1 in tissues other than the kidney is wide spread. However, the kid
Externí odkaz:
https://doaj.org/article/cce0e2f112a448c8acbb54dd23bbcd34
The Fracture Callus Is Formed by Progenitors of Different Skeletal Origins in a Site‐Specific Manner
Autor:
Yongmei Wang, Ling Chen, Misun Kang, Lin Ling, Faming Tian, Sun Hee Won‐Kim, Sunita Ho, Daniel D. Bikle
Publikováno v:
JBMR Plus, Vol 3, Iss 9, Pp n/a-n/a (2019)
ABSTRACT We evaluated repair following a mid‐diaphyseal fracture of the tibia in 3‐month‐old mice. We observed differences in the repair process at three different sites of the callus. Site 1: bone developing from the outer layer of the periost
Externí odkaz:
https://doaj.org/article/454a8eb4940a419ba740bd0294ddbf53
Autor:
Daniel D, Bikle
Publikováno v:
Reviews in Endocrine & Metabolic Disorders
Covid-19 has to date infected a confirmed 275 million people with 5.4 million, now dead, with the count rising every day. Although the virus, SARS-CoV2, causing Covid-19 infects many cells in the body, its infection of the upper and lower respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897488de53af0f281e2c753223caca1a
https://doi.org/10.1007/s11154-021-09707-4
https://doi.org/10.1007/s11154-021-09707-4
Publikováno v:
J Invest Dermatol
The Ca(2+)-sensing receptor (CaSR) drives essential Ca(2+) and E-cadherin-mediated processes in the epidermis, including differentiation (Komuves et al., 2002), cell-to-cell adhesion (Tu et al., 2008) and epidermal barrier homeostasis in cells and yo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915bcb25bc12cf1921b5fcc0c66b74fd
https://doi.org/10.1016/j.jid.2021.03.025
https://doi.org/10.1016/j.jid.2021.03.025