Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel Claudio Oliveira, Gomes"'
Autor:
Luciana Polaco Covre, Carlos Henrique Fantecelle, Renan Garcia de Moura, Paola Oliveira Lopes, Isabela Valim Sarmento, Celio Geraldo Freire-de-Lima, Debora Decote-Ricardo, Herbert Leonel de Matos Guedes, Alessandra Marcia da Fonsceca-Martins, Lucas Pedreira de Carvalho, Edgar Marcelino de Carvalho, David M. Mosser, Aloisio Falqueto, Arne N. Akbar, Daniel Claudio Oliveira Gomes
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic activity is a hallmark of the immunopathogenesis in human cutaneous leishmaniasis (CL). In this study, we identified accumulation of CD4+ granzyme B producing T cells with increased cytotoxic capacity in CL lesions. These cells showed enhan
Externí odkaz:
https://doaj.org/article/62e70576cb3d4ad59dcb11eebedd7965
Autor:
Pollyanna Stephanie Gomes, Monique Pacheco Duarte Carneiro, Patrícia de Almeida Machado, Valter Viana de Andrade-Neto, Alessandra Marcia da Fonseca-Martins, Amy Goundry, João Vitor Marques Pereira da Silva, Daniel Claudio Oliveira Gomes, Ana Paula Cabral de Araujo Lima, Vítor Ennes-Vidal, Ana Carolina Rennó Sodero, Salvatore Giovanni De-Simone, Herbert L. de Matos Guedes
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 5, Pp 2089-2106 (2022)
Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In Leishmania major and L. donovani, this enzyme has been described as essential to their survival; however, few compounds that
Externí odkaz:
https://doaj.org/article/14a0437ab2f54905977ef75da53f1211
Autor:
Alessandra M. da Fonseca-Martins, Phillipe de Souza Lima-Gomes, Maísa Mota Antunes, Renan Garcia de Moura, Luciana P. Covre, Carolina Calôba, Vivian Grizente Rocha, Renata M. Pereira, Gustavo Batista Menezes, Daniel Claudio Oliveira Gomes, Elvira M. Saraiva, Herbert L. de Matos Guedes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils play an important role in the outcome of leishmaniasis, contributing either to exacerbating or controlling the progression of infection, a dual effect whose underlying mechanisms are not clear. We recently reported that CD4+ and CD8+ T ce
Externí odkaz:
https://doaj.org/article/f78158f9c28a4a92b2530888bec4bdcc
Autor:
Renan Garcia de Moura, Luciana Polaco Covre, Carlos Henrique Fantecelle, Vitor Alejandro Torres Gajardo, Carla Baroni Cunha, Lorenzzo Lyrio Stringari, Ashton Trey Belew, Camila Batista Daniel, Sandra Ventorin Von Zeidler, Carlos Eduardo Tadokoro, Herbert Leonel de Matos Guedes, Raphael Lubiana Zanotti, David Mosser, Aloisio Falqueto, Arne N. Akbar, Daniel Claudio Oliveira Gomes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Patients infected by Leishmania braziliensis develop debilitating skin lesions. The role of inhibitory checkpoint receptors (ICRs) that induce T cell exhaustion during this disease is not known. Transcriptional profiling identified increased expressi
Externí odkaz:
https://doaj.org/article/d7475f9b3d034bcb940bc04b036e221c
Autor:
Diogo Oliveira-Maciel, Júlio Souza dos-Santos, Gabriel Oliveira-Silva, Mirian França de Mello, Alessandra Marcia da Fonseca-Martins, Monique Pacheco Duarte Carneiro, Tadeu Diniz Ramos, Luan Firmino-Cruz, Daniel Claudio Oliveira Gomes, Bartira Rossi-Bergmann, Herbert Leonel de Matos Guedes
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1272 (2021)
There is so far no vaccine approved for human leishmaniasis, mainly because of the lack of appropriate adjuvants. This study aimed to evaluate in mice the capacity of a mixture of monophosphoryl lipid A (MPLA) and AddaVax® adjuvants in enhancing the
Externí odkaz:
https://doaj.org/article/107c8e7ffa3d405d97e23d291dec8451
Autor:
Júlio Souza dos-Santos, Luan Firmino-Cruz, Tadeu Diniz Ramos, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Juliana Valente Rodrigues De-Medeiros, Suzana Passos Chaves, Daniel Claudio Oliveira Gomes, Herbert Leonel de Matos Guedes
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Leishmaniasis is a complex of neglected diseases caused by parasites of the genus Leishmania, such as Leishmania (Leishmania) amazonensis, the ethiologic agent of diffuse cutaneous leishmaniasis in Brazil. In this work, we investigated a new experime
Externí odkaz:
https://doaj.org/article/84ceda1418974230aac4ca9d062b3f74
Autor:
Izabella Pereira da Silva Bezerra, Gabriel Oliveira-Silva, Danielle Sophia Ferreira Santos Braga, Mirian França de Mello, Juliana Elena Silveira Pratti, Joyce Carvalho Pereira, Alessandra Marcia da Fonseca-Martins, Luan Firmino-Cruz, Diogo Maciel-Oliveira, Tadeu Diniz Ramos, André Macedo Vale, Daniel Claudio Oliveira Gomes, Bartira Rossi-Bergmann, Herbert Leonel de Matos Guedes
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The leishmaniases are a group of diseases caused by Leishmania parasites, which have different clinical manifestations. Leishmania (Leishmania) amazonensis is endemic in South America and causes cutaneous leishmaniasis (CL), which can evolve into a d
Externí odkaz:
https://doaj.org/article/0aa2763a6a3d45b4970b93706123982a
Publikováno v:
Immunological Reviews.
Autor:
Pollyanna Stephanie, Gomes, Monique Pacheco Duarte, Carneiro, Patrícia de Almeida, Machado, Valter Viana, de Andrade-Neto, Alessandra Marcia, da Fonseca-Martins, Amy, Goundry, João Vitor Marques, Pereira da Silva, Daniel Claudio Oliveira, Gomes, Ana Paula Cabral de Araujo, Lima, Vítor, Ennes-Vidal, Ana Carolina Rennó, Sodero, Salvatore Giovanni, De-Simone, Herbert L, de Matos Guedes
Publikováno v:
Current issues in molecular biology. 44(5)
Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In
Autor:
Carlos Henrique, Fantecelle, Luciana Polaco, Covre, Renan, Garcia de Moura, Herbert Leonel de Matos, Guedes, Camila Farias, Amorim, Phillip, Scott, David, Mosser, Aloisio, Falqueto, Arne N, Akbar, Daniel Claudio Oliveira, Gomes
Publikováno v:
Immunology
The severity of lesions that develop in patients infected by Leishmania braziliensis is mainly associated with a highly cytotoxic and inflammatory cutaneous environment. Recently, we demonstrated that senescent T and NK cells play a role in the estab