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pro vyhledávání: '"Daniel Chrobak"'
Publikováno v:
Journal of Biological Chemistry. 279:39895-39904
Although HOXB6 and other HOX genes have previously been associated with hematopoiesis and leukemias, the precise mechanism of action of their protein products remains unclear. Here we use a biological model in which HOXB6 represses alpha- and gamma-g
Publikováno v:
Sexually transmitted diseases. 41(4)
Autor:
Michelle M. Le Beau, Archana Radhakrishnan, Daniel Chrobak, H. Jeffrey Lawrence, Corey Largman, Neal Fischbach, Scott C. Kogan, S Rozenfeld, Wei-Fang Shen, Stephen Fong, David Ginzinger
Publikováno v:
Blood. 105(4)
The HOX family of homeobox genes plays an important role in normal and malignant hematopoiesis. Dysregulated HOX gene expression profoundly effects the proliferation and differentiation of hematopoietic stem cells (HSCs) and committed progenitors, an