Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Daniel Chargelegue"'
Publikováno v:
Journal of Biological Chemistry. 279:22198-22203
Guy's 13 is a mouse monoclonal antibody that specifically recognizes the major cell-surface adhesion protein SA I/II of Streptococcus mutans, one of the major causative agents of dental caries. Passive immunization with Guy's 13 prevents bacterial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaff2629f992481f6f9b2bebf870faf
https://doi.org/10.1074/jbc.m400820200
https://doi.org/10.1074/jbc.m400820200
Autor:
Patricia Obregon, Pascal M. W. Drake, Julian K.-C. Ma, Daniel Chargelegue, Nicholas D. Vine, Craig J. van Dolleweerd
Publikováno v:
Plant Molecular Biology. 52:233-241
The secretion of a functional, full-length monoclonal antibody complex from transgenic Nicotiana tabacum roots has been demonstrated. Initially, seeds were germinated on nitrocellulose membranes and antibody secretion detected from the developing roo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b476ffd5d21dffe36b499ed70284f993
https://doi.org/10.1023/a:1023909331482
https://doi.org/10.1023/a:1023909331482
Autor:
Julian K.-C. Ma, Craig J. van Dolleweerd, Nicholas D. Vine, Daniel Chargelegue, Pascal M. W. Drake, Patricia Obregon
Publikováno v:
The FASEB Journal. 16:1855-1860
The feasibility of using antibody expressing transgenic plants either to neutralize bioactive molecules in the rhizosphere, or to accumulate and concentrate the molecules in leaves has been demonstrated in a model system consisting of hydroponic Nico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83808cd813f1ccdbeb04db5f5f4e56b5
https://doi.org/10.1096/fj.02-0148com
https://doi.org/10.1096/fj.02-0148com
Publikováno v:
Transgenic Research. 9:187-194
Previous studies have shown that the production of recombinant antibodies in plants is highly efficient and presents numerous therapeutic applications. It is, however, known that plant glycoproteins display different glycosylation patterns to those e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bcf23121161555dd6d4edfaca6ec21
https://doi.org/10.1023/a:1008976219939
https://doi.org/10.1023/a:1008976219939
Autor:
James Nuttall, Daniel Chargelegue, Patricia Obregon, Lorenzo Frigerio, Julian K.-C. Ma, Alessandra Prada, Pascal M. W. Drake
Publikováno v:
Plant biotechnology journal. 4(2)
We describe the engineering of a human immunodeficiency virus-1 (HIV-1) p24-immunoglobulin A (IgA) antigen-antibody fusion molecule for therapeutic purposes and its enhancing effect on fused antigen expression in tobacco plants. Although many recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e0697a7f79477d1be27824c6dbfd33
https://pubmed.ncbi.nlm.nih.gov/17177796
https://pubmed.ncbi.nlm.nih.gov/17177796
Autor:
Patricia Obregon, Alessandra Prada, Julian K.-C. Ma, Daniel Chargelegue, Neil F. Fairweather, Pascal M. W. Drake
Vaccine development has been hampered by difficulties in developing new and safe adjuvants, so alternative technologies that offer new avenues forward are urgently needed. The goal of this study was to express a monoclonal recombinant immune complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9562bdfe21841926376c7b3488635
https://europepmc.org/articles/PMC1231086/
https://europepmc.org/articles/PMC1231086/
Publikováno v:
Molecular Farming: Plant-Made Pharmaceuticals and Technical Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8caf97f5650d11cd31ecd85fc2096da4
https://doi.org/10.1002/3527603638.ch10
https://doi.org/10.1002/3527603638.ch10
Publikováno v:
Vaccine. 23(15)
The use of transgenic plants for the production of recombinant proteins is not a universal solution for all proteins. The choice of this expression system depends very much on the type of protein and its applications. Many proteins will best be made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f217a35c073412041f4005d799ff358a
https://pubmed.ncbi.nlm.nih.gov/15734047
https://pubmed.ncbi.nlm.nih.gov/15734047
Publikováno v:
Infection and immunity. 71(2)
Guy's 13 is a mouse monoclonal antibody which recognizes streptococcal antigen I/II (SA I/II), a major cell surface glycoprotein of Streptococcus mutans . In a number of clinical trials, this antibody has been shown to prevent colonization in the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3377abd40e0a77f2bbe7438b2c6c891e
https://pubmed.ncbi.nlm.nih.gov/12540555
https://pubmed.ncbi.nlm.nih.gov/12540555
Autor:
Patricia Obregon, Julian K.-C. Ma, Daniel Chargelegue, Alessandra Prada, Pascal M. W. Drake, Lorenzo Frigerio
Publikováno v:
Plant Biotechnology 2002 and Beyond ISBN: 9789048162208
There is increasing interest in transgenic plant technology for the production of a wide range of recombinant proteins for pharmaceutical and industrial uses. There are many potential benefits in using plants as bioreactors for the production of such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb4912637e29ad009e440ec147be5204
https://doi.org/10.1007/978-94-017-2679-5_75
https://doi.org/10.1007/978-94-017-2679-5_75