Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel Cervantes-Laurean"'
Publikováno v:
Free Radical Biology and Medicine. 50:1410-1416
A number of oxidative stress agents cause DNA and protein damage, which may compromise genomic integrity. Whereas oxidant-induced DNA damage has been extensively studied, much less is known concerning the occurrence and fate of nuclear protein damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdf37c83c3c743e2cb9750b81ecea77
https://doi.org/10.1016/j.freeradbiomed.2011.01.034
https://doi.org/10.1016/j.freeradbiomed.2011.01.034
Publikováno v:
Free Radical Biology and Medicine. 48:656-663
Glycation is a nonenzymatic condensation reaction between reducing sugars and amino groups of proteins that undergo rearrangements to stable ketoamines, leading to the formation of advanced glycation end products (AGEs) including fluorescent (argpyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ccc0c3ffb81717590823d11d85c1841
https://doi.org/10.1016/j.freeradbiomed.2009.11.019
https://doi.org/10.1016/j.freeradbiomed.2009.11.019
Autor:
Georg T. Wondrak, Moonsun Kim, Michael J. Roberts, Elaine L. Jacobson, Daniel Cervantes-Laurean, Jaber G. Qasem, Myron K. Jacobson
Publikováno v:
Biochemical Pharmacology. 63:361-373
Tissue deterioration and aging have long been associated with the accumulation of chemically induced protein and DNA damage. Reactive oxygen species (ROS) and reactive carbonyl species (RCS), especially alpha-dicarbonyl compounds, are key mediators o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf62d2e9af5da025289bfdb63ec801e9
https://doi.org/10.1016/s0006-2952(01)00915-7
https://doi.org/10.1016/s0006-2952(01)00915-7
Publikováno v:
Biochemical Journal. 351:769-777
Non-enzymic damage to nuclear proteins has potentially severe consequences for the maintenance of genomic integrity. Introduction of carbonyl groups into histones in vivo and in vitro was assessed by Western blot immunoassay and reductive incorporati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418a8151270550fe70e1d232ce1e59c0
https://doi.org/10.1042/bj3510769
https://doi.org/10.1042/bj3510769
Publikováno v:
Journal of Biological Chemistry. 271:10461-10469
The reaction of long lived proteins with reducing sugars has been implicated in the pathophysiology of aging and age-related diseases. A likely intranuclear source of reducing sugar is ADP-ribose, which is generated following DNA damage from the turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab0a71738cccd281bf93012c6d0c038
https://doi.org/10.1074/jbc.271.18.10461
https://doi.org/10.1074/jbc.271.18.10461
Publikováno v:
Molecular and Cellular Biochemistry. 138:207-212
Numerous metabolic pathways generate free ADP-ribose at many locations within cells. The metabolic fates of this nucleotide are poorly understood and measurement of it in situ is technically difficult at present. Yet considerable evidence has accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88634d42388c45e058b45664a743e433
https://doi.org/10.1007/bf00928463
https://doi.org/10.1007/bf00928463
Autor:
Daniel Cervantes Laurean
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d614b51e9fce6b0997cb4edb7b5c4aa3
https://doi.org/10.1096/fasebj.23.1_supplement.863.6
https://doi.org/10.1096/fasebj.23.1_supplement.863.6
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8eb14385ce58c1e52cb79a7e0cd0f8e
https://doi.org/10.1096/fasebj.22.1_supplement.614.12
https://doi.org/10.1096/fasebj.22.1_supplement.614.12
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1b3ba3cc7492c01a686290cfb05f0f
https://doi.org/10.1096/fasebj.21.5.a633-a
https://doi.org/10.1096/fasebj.21.5.a633-a
Autor:
Daniel Cervantes-Laurean, Derek D. Schramm, Ihab Halaweish, Geza Bruckner, Gilbert A. Boissonneault, Elaine L. Jacobson
Publikováno v:
The Journal of nutritional biochemistry. 17(8)
Several lines of evidence suggest that rutin, flavonoid in fruits and vegetables, or one of its metabolites may effectively modulate advanced glycation end product (AGE) formation. Following ingestion, rutin forms metabolites that include 3,4-dihydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7cc66fbdae7f1fe935484b47c56467
https://pubmed.ncbi.nlm.nih.gov/16443355
https://pubmed.ncbi.nlm.nih.gov/16443355