Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Daniel Cannon"'
Autor:
Daniel Cannon, Bojana Popovic, D. Gareth Rees, Ralph Minter, Andrew Buchanan, Kalliopi Skamaki, Stéphane Emond, John Andrews, Florian Hollfelder, Matthieu Chodorge
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences
We report a systematic combinatorial exploration of affinity enhancement of antibodies by insertions and deletions (InDels). Transposon-based introduction of InDels via the method TRIAD (transposition-based random insertion and deletion mutagenesis)
Autor:
Mr Daniel Cannon, Ms Leanne McNamara, Ms Marijn Rolf, Ms Caroline Lannon, Ms Aoife Gaffney, Ms Aoife Gallagher
Publikováno v:
Physica Medica. 104:S135
Autor:
Bojana Popovic, Matthieu Chodorge, John Andrews, Kalliopi Skamaki, Stéphane Emond, Florian Hollfelder, Ralph Minter, Daniel Cannon, D. Gareth Rees, Andrew Buchanan
We report the first systematic combinatorial exploration of affinity enhancement of antibodies by insertions and deletions (InDels). Transposon-based introduction of InDels via the method TRIAD was used to generate large libraries with random in-fram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89427c3e68fe19a5e3e54d9fc032bf0
https://doi.org/10.1101/2020.04.26.062786
https://doi.org/10.1101/2020.04.26.062786
Autor:
Niall Sheehy, Andrew J. Fagan, Daniel Foley, Daniel Cannon, Jacinta E. Browne, James F. Meaney, Xiahai Zhuang, Dearbhail O'Driscoll, Barry Sheane
Publikováno v:
Articles
Purpose An investigation was carried out into the effect of three image registration techniques on the diagnostic image quality of contrast-enhanced magnetic resonance angiography (CE-MRA) images. Methods Whole-body CE-MRA data from the lower legs of
Autor:
Daniel Cannon, Hiroshi Matsui, Rein V. Ulijn, Yoshiaki Maeda, Kirsty F. Gibson, Krystyna Duncan, Charles W. Knapp, Tell Tuttle, Nadeem Javid, Louise S. Birchall, Yuka Kanetsuki
Publikováno v:
Journal of the American Chemical Society. 136:15893-15896
Discovery of new catalysts for demanding aqueous reactions is challenging. Here, we describe methodology for selection of catalytic phages by taking advantage of localized assembly of the product of the catalytic reaction that is screened for. A phag
Autor:
Kim Rosenthal, Andrew Buchanan, Lilian E. van Vlerken-Ysla, Tristan J Vaughan, Bojana Popovic, Qun Du, Lena Shirinian, Martin Korade, Daniel Cannon, Keith W. Rickert, Lu Shan, Melissa Damschroder
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 5, p e1006980 (2019)
PLoS Computational Biology
PLoS Computational Biology
Antibodies are an important class of therapeutics that have significant clinical impact for the treatment of severe diseases. Computational tools to support antibody drug discovery have been developing at an increasing rate over the last decade and t
Publikováno v:
Computational and Theoretical Chemistry. 1010:19-24
The formation of bimolecular complexes of HOOOH and the HOOOﰀ radical with sulfuric acid (H2SO4– HOOOH, H2SO4–HOOOﰀ) has been investigated by using DFT (B3LYP/6-311++G(3df,3pd)) and CCSD(T)- F12 methods. For the first time the structures and
Autor:
Daniel Cannon, Dimitrios A. Lamprou, Rein V. Ulijn, Meghan Hughes, Tell Tuttle, Ivan R. Sasselli, Inês Pimentel Moreira
We report on-demand formation of emulsions stabilised by interfacial nanoscale networks. These are formed through biocatalytic dephosphorylation and self-assembly of Fmoc(9-fluorenylmethoxycarbonyl)-dipeptide amphiphiles in aqueous/organic mixtures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175c8b0739d886fcb12db0b293e7e972
https://strathprints.strath.ac.uk/55388/1/Moreira_etal_SM_2016_Enzymatically_activated_emulsions_stabilized_by_interfacial.pdf
https://strathprints.strath.ac.uk/55388/1/Moreira_etal_SM_2016_Enzymatically_activated_emulsions_stabilized_by_interfacial.pdf
Publikováno v:
The journal of physical chemistry letters. 6(19)
Protein binding to surfaces is an important phenomenon in biology and in modern technological applications. Extensive experimental and theoretical research has been focused in recent years on revealing the factors that govern binding affinity to surf
Autor:
Alan R. Kennedy, Robert E. Mulvey, Stuart D. Robertson, Tell Tuttle, Daniel Cannon, Joerg Sassmannshausen, Ross Campbell, Pablo García-Álvarez
Publikováno v:
Journal of the American Chemical Society
The surprising transformation of the saturated diamine (iPr)NHCH(2)CH(2)NH(iPr) to the unsaturated diazaethene [(iPr)NCH═CHN(iPr)](2-) via the synergic mixture nBuM, (tBu)(2)Zn and TMEDA (where M = Li, Na; TMEDA = N,N,N',N'-tetramethylethylenediami