Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel Cancilla"'
Autor:
Eric M Jones, Nathan B Lubock, AJ Venkatakrishnan, Jeffrey Wang, Alex M Tseng, Joseph M Paggi, Naomi R Latorraca, Daniel Cancilla, Megan Satyadi, Jessica E Davis, M Madan Babu, Ron O Dror, Sriram Kosuri
Publikováno v:
eLife, Vol 9 (2020)
The >800 human G protein–coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make it
Externí odkaz:
https://doaj.org/article/eef860197db949eb8e173ad8316b333e
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The interaction of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as well as chemotherapy resistance. The chemokine receptor, CXC receptor 4 (
Externí odkaz:
https://doaj.org/article/4abf6bc64764492391d8513edc68c0a1
Autor:
Leah Gehrs, Dwight M. Morrow, David W. Griggs, Stephanie Christ, Andreas Trumpp, Richard F. Heier, Eliza Wiercinska, Halvard Bonig, Moses O. Evbuomwan, Darja Karpova, Peter G. Ruminski, Julie Ritchey, Michael P. Rettig, Feng Gao, Daniel Cancilla, Ezhilarasi Chendamarai, Michael J. Prinsen, Hamza Celik, Grazia Abou-Ezzi, Daniel C. Link, John F. DiPersio, Marvin J. Meyers, Wei Yang, Stacy D. Arnett, Jingzhu Zhang, Matthew Holt, Linda Eissenberg
Publikováno v:
Journal of Clinical Investigation. 129:2745-2759
Mobilized peripheral blood has become the primary source of hematopoietic stem and progenitor cells (HSPCs) for stem cell transplantation, with a 5-day course of granulocyte colony-stimulating factor (G-CSF) as the most common regimen used for HSPC m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76508116b9efbe2c446f322074178732
https://doi.org/10.1172/jci124738
https://doi.org/10.1172/jci124738
Autor:
M. Madan Babu, Jessica E. Davis, Ron O. Dror, Naomi R. Latorraca, Megan Satyadi, Joseph M. Paggi, Daniel Cancilla, Alex M. Tseng, Jeffrey C. Wang, AJ Venkatakrishnan, Nathan B. Lubock, Sriram Kosuri, Eric M. Jones
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
In humans, the 813 G protein-coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state, and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b668625995cc537ec6a62730742799
https://escholarship.org/uc/item/6971x0wv
https://escholarship.org/uc/item/6971x0wv
Autor:
Alex M. Tseng, Megan Satyadi, Daniel Cancilla, Ron O. Dror, Joseph M. Paggi, M. Madan Babu, Sriram Kosuri, AJ Venkatakrishnan, Eric M. Jones, Jessica E. Davis, Jeffrey C. Wang, Naomi R. Latorraca, Nathan B. Lubock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b84920d04a82111281bead63193d0f8
https://doi.org/10.7554/elife.54895.sa2
https://doi.org/10.7554/elife.54895.sa2
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The interaction of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as well as chemotherapy resistance. The chemokine receptor, CXC receptor 4 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051a2320165b20e269ce16c2b583d804
https://www.frontiersin.org/article/10.3389/fonc.2020.01672/full
https://www.frontiersin.org/article/10.3389/fonc.2020.01672/full
Autor:
Daniel Cancilla, Sriram Kosuri, Jeffrey C. Wang, Joshua S. Bloom, Hiroaki Matsunami, Nathan B. Lubock, Rishi Jajoo, Rocky Cheung, Eric M. Jones, Claire A. de March, Megan Satyadi
Publikováno v:
Cell systems. 8(3)
G-protein coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the largest family of GPCRs, mediate the sense of smell through activation by small molecules, though for most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577e86a8f84d2f10d3c3edccfc4417ab
https://pubmed.ncbi.nlm.nih.gov/30904378
https://pubmed.ncbi.nlm.nih.gov/30904378
Autor:
Eric M. Jones, Nathan B. Lubock, Hiroaki Matsunami, Daniel Cancilla, Jingge Wang, de March C, Sriram Kosuri, Jajoo R, Rocky Cheung, Megan Satyadi
Chemicals such as drugs, hormones, and odorants can have many potential interactions with endogenous targets, and uncovering these relationships is critical for understanding and modulating function. Mammalian olfactory receptors (ORs), a large famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2c4e9658bb3a0b172cce17a1895089
https://doi.org/10.1101/358739
https://doi.org/10.1101/358739
Autor:
Stephanie Christ, Michael P. Rettig, Haresh Thakellapalli, Ezhilarasi Chendamarai, Dwight M. Morrow, John F. DiPersio, Daniel Cancilla, Peter G. Ruminski, Darja Karpova, Julie Ritchey, Michael J. Prinsen, Marvin J. Meyers
Publikováno v:
Blood. 134:1916-1916
Background: Hematopoietic stem cell (HSC) transplant is an essential treatment for a variety of blood disorders and malignancies. A key step in this procedure is the mobilization of donor stem cells. The most commonly used regimen for donor mobilizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a82a8c5830a62edda669f01fa74f5aba
https://doi.org/10.1182/blood-2019-124373
https://doi.org/10.1182/blood-2019-124373