Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniel C.F. Chan"'
Autor:
Daniel C.F. Chan, Benjamin L. Barthel, Margaret Polinkovsky, Zhiyong Zhang, Gary G. Koch, Tad H. Koch, Hengrui Sun, Daniel L. Rudnicki, Christopher D. Coldren
Publikováno v:
Journal of Medicinal Chemistry. 52:7678-7688
Doxazolidine (Doxaz) is a functionally distinct formaldehyde conjugate of doxorubicin (Dox) that induces cancer cell death in Dox-sensitive and resistant cells. Pentyl PABC-Doxaz (PPD) is a prodrug of Doxaz that is activated by carboxylesterase 2 (CE
Publikováno v:
Journal of Magnetism and Magnetic Materials. 122:374-378
A panel of water-based colloidal magnetic iron oxides was synthesized, and specific power absorption rates of the synthesized ferrofluids were studied in the magnetic fields of various strength and frequency. The ferrofluids displayed superior heatin
Publikováno v:
Breast Cancer Research & Treatment; May2004, Vol. 85 Issue 1, p1-12, 12p
Autor:
Lawrence H. Piette, Daniel C.F. Chan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 623:32-45
An imidazole spin label has been used to study the accessibility and conformational state of tyrosines in both the nucleosome core particles and histone core extracted from chicken erythrocytes. About 40% of the tyrosyl residues in the histone core c
Autor:
Daniel C.F. Chan, Lawrence H. Piette
Publikováno v:
Biochemistry. 21:3028-3035
An imidazole spin-label was used to study the role of tyrosyl residues in the reassociation process for the nucleosome core particle. The nucleosome core particle, containing 145 base pairs of DNA and a histone core (two each of the four histones H2S
Publikováno v:
Nucleic Acids Research. 3:2879-2894
This study compares some physical properties of DNA in native chromatin and mono-, di-, trinucleosomes obtained after mild micrococcal nuclease digestion. Melting curves and derivatives are shown to be very similar from one sample to another although
Autor:
Daniel C.F. Chan, Lawrence H. Piette, Jean-Luc Girardet, Claude Gorka, Jean-Jacques Lawrence, Joelle Biard-Roche
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 2:319-332
Histone H5 contains three tyrosines in the central, apolar region of the molecule. All three tyrosines can be spin labeled at low ionic strength. When the central globular domain is folded at high ionic strength, only one tyrosine becomes accessible
Publikováno v:
Biophysical Journal. 32:454-455
The spin label, N-(2,2,5,5-tetramethyl-3-carbonylpyrrolidine-1-oxyl)-imidazole, was used to study the mode of reconstitution of nucleosome core particles. The histone cores in 2 M NaCl were first reacted with the imidazole spin label. After the remov