Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daniel C. Turnock"'
Autor:
Alan R. Prescott, M. Lucia S. Güther, Magnus S. Alphey, Michael A. J. Ferguson, Daniel C. Turnock, Kirstee L. Martin, Matthew J. Stokes
Publikováno v:
The Journal of Biological Chemistry
A gene encoding Trypanosoma brucei UDP-N-acetylglucosamine pyrophosphorylase was identified, and the recombinant protein was shown to have enzymatic activity. The parasite enzyme is unusual in having a strict substrate specificity for N-acetylglucosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228c12eab3ac21aa62daea1356c77121
http://europepmc.org/articles/PMC2414269
http://europepmc.org/articles/PMC2414269
Publikováno v:
Journal of Biological Chemistry. 282:28853-28863
The protozoan parasite Trypanosoma brucei causes human African sleeping sickness in sub-Saharan Africa. The parasite makes several essential glycoproteins, which has led to the investigation of the sugar nucleotides and glycosyltransferases required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064faa193bda3fadc334412512de43a2
https://doi.org/10.1074/jbc.m704742200
https://doi.org/10.1074/jbc.m704742200
Autor:
Michael A. J. Ferguson, James I. MacRae, Samson O. Obado, Daniel C. Turnock, John M. Kelly, Janine R. Roper, Martin Kierans
Publikováno v:
Molecular and Biochemical Parasitology. 147:126-136
The cell surface of the epimastigote form of Trypanosoma cruzi is covered by glycoconjugates rich in galactose. The parasite cannot take up galactose through its hexose transporter, suggesting that the epimerisation of UDP-glucose to UDP-galactose ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe458cb596fdb378d14de62e6aea654
https://doi.org/10.1016/j.molbiopara.2006.02.011
https://doi.org/10.1016/j.molbiopara.2006.02.011
Autor:
Daniel Mariappa, H.-Arno J. Müller, Karina Mariño, Michael A. J. Ferguson, Ryan Webster, Kathrin Sauert, Daniel C. Turnock, Daan M. F. van Aalten
Glycosylation is essential for growth factor signaling through N-glycosylation of ligands and receptors and the biosynthesis of proteoglycans as co-receptors. Here, we show that protein O-GlcNAcylation is crucial for fibroblast growth factor (FGF) si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ade3652e6692ac978b8240ac9c8942
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84255190077
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84255190077
The cell surface glycoconjugates of trypanosomatid parasites are intimately involved in parasite survival, infectivity, and virulence in their insect vectors and mammalian hosts. Although there is a considerable body of work describing their structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896fc312df95051f6c5b24a5c8a5c594
https://europepmc.org/articles/PMC1951125/
https://europepmc.org/articles/PMC1951125/
Publikováno v:
Eukaryotic cell. 5(11)
Galactose metabolism is essential for the survival of Trypanosoma brucei , the etiological agent of African sleeping sickness. T. brucei hexose transporters are unable to transport galactose, which is instead obtained through the epimerization of UDP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e50cedc66935a1ce53bdd715cb5d5c2
https://pubmed.ncbi.nlm.nih.gov/17093269
https://pubmed.ncbi.nlm.nih.gov/17093269
Autor:
Sujatha Manthri, Deuan C. Jones, Angela Mehlert, Izquierdo Luis, Lucia Sampaio Guther, Daniel C. Turnock, Michael Anthony Ferguson, Matthew J. Stokes
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bafe0318750e9194690cc05dd4b51d9
https://doi.org/10.1096/fasebj.20.4.a454
https://doi.org/10.1096/fasebj.20.4.a454