Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Daniel C Pregibon"'
Autor:
Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background High-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restri
Externí odkaz:
https://doaj.org/article/8563618d2440465aa2a5fd3a1eb10376
Autor:
Joshua M, Francis, Del, Leistritz-Edwards, Augustine, Dunn, Christina, Tarr, Jesse, Lehman, Conor, Dempsey, Andrew, Hamel, Violeta, Rayon, Gang, Liu, Yuntong, Wang, Marcos, Wille, Melissa, Durkin, Kane, Hadley, Aswathy, Sheena, Benjamin, Roscoe, Mark, Ng, Graham, Rockwell, Margaret, Manto, Elizabeth, Gienger, Joshua, Nickerson, Amir, Moarefi, Michael, Noble, Thomas, Malia, Philip D, Bardwell, William, Gordon, Joanna, Swain, Mojca, Skoberne, Karsten, Sauer, Tim, Harris, Ananda W, Goldrath, Alex K, Shalek, Anthony J, Coyle, Christophe, Benoist, Daniel C, Pregibon
Publikováno v:
Science immunology. 7(67)
Effective presentation of antigens by human leukocyte antigen (HLA) class I molecules to CD8
Autor:
Yuntong Wang, Mojca Skoberne, Joshua Nickerson, Margaret Manto, Gordon William Michael, Tim Harris, Anthony J Coyle, Elizabeth Gienger, Philip Bardwell, Michael Noble, Joshua M. Francis, Augustine Dunn, Andrew R Hamel, Ananda W. Goldrath, Kane Hadley, Jesse Lehman, Christophe Benoist, Marcos Wille, Graham Rockwell, Alex K. Shalek, Daniel C. Pregibon, Mark Ng, Melissa R. Durkin, Thomas Malia, Christina Tarr, Benjamin P. Roscoe, Karsten Sauer, Conor Dempsey, Del Leistritz-Edwards, Aswathy Sheen, Amir Moarefi, Violeta Rayon, Gang Liu, Joanna Swain
Effective presentation of antigens by HLA class I molecules to CD8+ T cells is required for viral elimination and generation of long-term immunological memory. In this study, we applied a single-cell, multi-omic technology to generate the first unifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d291c8d3daa97a32752a5f5a9b9fbd
https://doi.org/10.1101/2021.04.29.441258
https://doi.org/10.1101/2021.04.29.441258
Autor:
Dan H. Barouch, Karl R. Clauser, Aharon Nachshon, Kendall M. Lavin-Parsons, Matteo Gentili, Nina Bhardwaj, Jessica Tantivit, Moshe Sade-Feldman, Kathleen Gallagher, Irena Gushterova, Maricarmen Rojas-Lopez, Mary Carrington, Anna L.K. Gonye, Brenna N. McKaig, Nir Hacohen, Tom Lasalle, Derin B. Keskin, Daniel C. Pregibon, Marcela V. Maus, Da Yuan Chen, Isabel P. Carulli, Abishek Chandrashekar, Leah R. Pearlman, Yuntong Wang, Katelin Katsis, Blair Parry, Hannah B. Taylor, Charles M. Rice, Mohsan Saeed, Brendan Lilley, Melissa R. Durkin, Nihaarika Sharma, Nicole Charland, Susan Klaeger, Vipheaviny Chea, Yaara Finkel, Molly Thomas, Christina Tarr, Steven A. Carr, Brian C. Russo, Pardis C. Sabeti, Del Leistritz-Edwards, Suzanna Rachimi, Alessandro Sette, Hasahn L. Conway, Hargun Khanna, Siranush Sarkizova, Kasidet Manakongtreecheep, Christopher Tomkins-Tinch, John Sidney, Keith Rivera, Justin D. Margolin, Jennifer G. Abelin, Carl Lodenstein, Matthew R. Bauer, Cansu Cimen Bozkus, W. Augustine Dunn, Shira Weingarten-Gabbay
Publikováno v:
Cell
T cell-mediated immunity plays an important role in controlling SARS-CoV-2 infection; yet the repertoire of naturally processed and presented viral epitopes on HLA class I remains uncharacterized. Here, we report the first HLA-I immunopeptidome of SA
Autor:
Florian Renoux, Phil Bardwell, Erika Hamilton, Mojca Skoberne, Parul Agnihotri, George R. Blumenschein, Daniel C. Pregibon, John David Pajerowski, William J. Gordon, Josh Francis, Christina Tarr, Nastassja Cerreghetti-Terraneo, Sarah Nikiforow, Keren Osman, Anthony J. Coyle, Anthony F. Shields, Marisa Loi, Sebastian Heer, Jan Kisielow, Harriet M. Kluger, Franz-Josef Obermair, Christine McInnis, Tabasum Huseni, Mihaela Christea, Ji Young Hwang
Publikováno v:
Cancer Research. 81:LB027-LB027
PRIME IL-15 (RPTR-147) is a novel non-genetically modified, autologous, multi-clonal T cell product loaded with an IL-15Fc nanogel. The product is derived from peripheral T cells that are primed and expanded against five tumor associated antigens (TA
Autor:
Michael R. Tackett, Elnaz Atabakhsh, Matt Camilleri, Bianca Heinrich, James Murray, Daniel C. Pregibon, Long To, Conor Rafferty, Russell Neuner, Amy Perea, Graeme Doran, Wayne Austin
Publikováno v:
Cancer Research. 79:4060-4060
In patients and animal models, molecular biomarkers are used as indicators of normal and pathogenic processes. In drug discovery and screening pipelines, molecular biomarkers are used to assess the mechanism of action, efficacy, and toxicity of lead
Autor:
Daniel C. Pregibon, Tamara Floyd-Smith, Stephen C. Chapin, Ki Wan Bong, David Baah, Patrick S. Doyle
Publikováno v:
Lab Chip. 11:743-747
We present the construction and operation of a compressed-air driven flow system that can be used for a variety of microfluidic applications that require rapid dynamic response and precise control of multiple inlet streams. With the use of inexpensiv
Autor:
Daniel C. Pregibon, Jordan Plieskatt
Publikováno v:
Genetic Engineering & Biotechnology News. 36:16-17
Autor:
Elnaz Atabakhsh, Daniel C. Pregibon, Gensis Tejada, Izzuddin Diwan, Ivona Kelley, Conor Rafferty, Michael R. Tackett
Publikováno v:
Cancer Research. 78:5405-5405
To address the needs for microRNA (miRNA) biomarker discovery and verification, we developed the FirePlex® miRNA assay. This assay enables the detection of 5-400 miRNA targets per sample in 96-well format, with readout on standard flow cytometers an
Publikováno v:
Angewandte Chemie International Edition. 49:87-90
Anisotropic multifunctional particles hold great promise for drug delivery, imaging, and construction of building blocks for dynamic mesostructures such as self-assembled tissues and 3-D electrical circuits. Of particular interest, multifunctional pa