Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Daniel C Bowers"'
Autor:
Nathanya Baez Hernandez, Ksenya Shliakhtsitsava, Drishti Tolani, Cindy Cochran, Ryan Butts, Judith Bonifacio, Elizabeth Journey, Jenna N. Oppenheim, Sarah G. Pennant, Kimberly Arnold, Terri McCaskill, Daniel C. Bowers
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Cardiovascular complications related to cancer therapies are broad and variable in onset. These complications are the leading cause of non-cancer related morbidity and mortality in childhood cancer survivors and can also impact ongoing cance
Externí odkaz:
https://doaj.org/article/3b7033772fc647adbc452e394c6aa38f
Autor:
Stefanie C. Vuotto, Mingjuan Wang, M. Fatih Okcu, Daniel C. Bowers, Nicole J. Ullrich, Kirsten K. Ness, Chenghong Li, Deo Kumar Srivastava, Rebecca M. Howell, Todd M. Gibson, Wendy M. Leisenring, Kevin C. Oeffinger, Leslie L. Robison, Gregory T. Armstrong, Kevin R. Krull, Tara M. Brinkman
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 291-301 (2024)
Abstract Objective To examine associations between neurologic late effects and attainment of independence in adult survivors of childhood cancer treated with central nervous system (CNS)‐directed therapies. Methods A total of 7881 survivors treated
Externí odkaz:
https://doaj.org/article/c7c62c5015f34b6083e66e661eb2a49e
Autor:
Anthony P. Y. Liu, Sandeep K. Dhanda, Tong Lin, Edgar Sioson, Aksana Vasilyeva, Brian Gudenas, Ruth G. Tatevossian, Sujuan Jia, Geoffrey Neale, Daniel C. Bowers, Tim Hassall, Sonia Partap, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Geoff McCowage, Alberto Broniscer, Ibrahim Qaddoumi, Greg Armstrong, Karen D. Wright, Santhosh A. Upadhyaya, Anna Vinitsky, Christopher L. Tinkle, John Lucas, Jason Chiang, Daniel J. Indelicato, Robert Sanders, Paul Klimo, Frederick A. Boop, Thomas E. Merchant, David W. Ellison, Paul A. Northcott, Brent A. Orr, Xin Zhou, Arzu Onar-Thomas, Amar Gajjar, Giles W. Robinson
Publikováno v:
Acta Neuropathologica. 144:733-746
Methylation profiling has radically transformed our understanding of tumors previously called central nervous system primitive neuro-ectodermal tumors (CNS-PNET). While this marks a momentous step toward defining key differences, reclassification has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de637cda9026768842fa1f9a26a7ce19
https://doi.org/10.1007/s00401-022-02484-7
https://doi.org/10.1007/s00401-022-02484-7
Autor:
Daniel C Bowers, Veena Rajaram, Matthias A Karajannis, Sharon L Gardner, Jack Meng-Fen Su, Patricia Baxter, Sonia Partap, Laura J Klesse
Publikováno v:
Neuro-Oncology Advances. 5
BackgroundPreclinical studies have suggested that mTOR pathway signaling may be a potential therapeutic target for childhood ependymoma.MethodsA phase II clinical trial (ClinicalTrials.gov identifier: NCT02155920) of single-agent everolimus was perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40f2f61450243900a3676f914e80993
https://doi.org/10.1093/noajnl/vdad011
https://doi.org/10.1093/noajnl/vdad011
Autor:
Netteke Schouten-van Meeteren, Katrin Scheinemann, Ranjeev Bhangoo, Pieter M. Pretorius, Gregory T. Armstrong, Daniel C. Bowers, Riccardo Haupt, W. Hamish B. Wallace, Kevin C. Oeffinger, Andrew W. Walter, Antony Ng, Michael M. Hawkins, Raja B. Khan, Helen Jenkinson, Jop C Teepen, Raoul C. Reulen, Leontien C. M. Kremer, Noah D. Sabin, Elaine Sugden, Renée L. Mulder, Melissa M. Hudson, Paul Klimo, Helena J H van der Pal, Zsila Sadighi, Cécile M. Ronckers, Roderick Skinner, Louis S. Constine, Nicole J. Ullrich, Lisanne C Verbruggen
Publikováno v:
The Lancet Oncology. 22:e196-e206
Exposure to cranial radiotherapy is associated with an increased risk of subsequent CNS neoplasms among childhood, adolescent, and young adult (CAYA) cancer survivors. Surveillance for subsequent neoplasms can translate into early diagnoses and inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cde9903f331946ab57aee53109949f9
https://doi.org/10.1016/s1470-2045(20)30688-4
https://doi.org/10.1016/s1470-2045(20)30688-4
Autor:
Lisa Mayr, Maria Trissal, Kallen Schwark, Jenna Labelle, Andrew Groves, Julia Furtner-Srajer, Jeffrey Supko, Liesa Weiler-Wichtl, Olivia Hack, Jacob Rozowsky, Joana G. Marques, Eshini Pandatharatna, Ulrike Leiss, Verena Rosenmayr, Frank Dubois, Noah F. Greenwald, Sibylle Madlener, Armin S. Guntner, Hana Pálová, Natalia Stepien, Daniela Lötsch-Gojo, Christian Dorfer, Karin Dieckmann, Andreas Peyrl, Amedeo A. Azizi, Alicia Baumgartner, Ondřej Slabý, Petra Pokorná, Pratiti Bandopadhayay, Rameen Beroukhim, Keith Ligon, Christof Kramm, Annika Bronsema, Simon Bailey, Ana Guerreiro Stücklin, Sabine Mueller, David T. Jones, Natalie Jäger, Jaroslav Štěrba, Leonhard Müllauer, Christine Haberler, Chandan Kumar-Sinha, Arul Chinnaiyan, Rajen Mody, Mary Skrypek, Nina Martinez, Daniel C. Bowers, Carl Koschmann, Johannes Gojo, Mariella Filbin
Publikováno v:
Cancer Research. 83:5719-5719
PDGFRA has been shown to be commonly altered in high-grade gliomas (HGGs), including histone 3 lysine 27-mutated diffuse midline gliomas (H3K27M DMG), a disease with almost no long-term survivors. Here, we performed comprehensive genomic and transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf322da6d6483a8d6cc3fedc3d8653e6
https://doi.org/10.1158/1538-7445.am2023-5719
https://doi.org/10.1158/1538-7445.am2023-5719
Autor:
Cynthia Hawkins, Daniel A. Morgenstern, Victoria J. Forster, Scott Lindhorst, Sumedha Sudhaman, Uri Tabori, An Van Damme, Eric Bouffet, Alexander Lossos, Ben George, Annika Bronsema, Anita Villani, Michael Osborn, Annie Huang, Yosef E. Maruvka, Melyssa Aronson, Patrick Tomboc, Michal Yalon-Oren, David S. Ziegler, Reid Hayes, Carol Durno, Vanessa Bianchi, Melissa Galati, Nuno Miguel Nunes, Magimairajan Issai Vanan, Vanja Cabric, Gregory Thomas, Nicholas Light, Scott Davidson, Matthew Zatzman, Michael D. Taylor, A. Sorana Morrissy, Martin Komosa, Melissa Edwards, Gary Mason, Jiil Chung, Adam Shlien, Gad Getz, Shriya Deshmukh, Alyssa Reddy, Karl P. Hodel, Zachary F. Pursell, Robert Siddaway, Maura Massimino, Enrico Opocher, Ledia Brunga, David Malkin, Ben Ho, Jacalyn Kelly, Daniel C. Bowers, Nathaniel D. Anderson, Valerie Larouche, Thomas A. Kunkel, Nicholas J. Haradhvala, Kristina A. Cole
Publikováno v:
Cancer Discov
Cancer discovery, Vol. 11, no. 5, p. 1176-1191 (2021)
Cancer discovery, Vol. 11, no. 5, p. 1176-1191 (2021)
Although replication repair deficiency, either by mismatch repair deficiency (MMRD) and/or loss of DNA polymerase proofreading, can cause hypermutation in cancer, microsatellite instability (MSI) is considered a hallmark of MMRD alone. By genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de55153537729f642eb68eecd06318c8
https://doi.org/10.1158/2159-8290.cd-20-0790
https://doi.org/10.1158/2159-8290.cd-20-0790
Autor:
Daniel C. Bowers, Osama Mohamad, Robert Timmerman, Strahinja Stojadinovic, Laura J. Klesse, Zabi Wardak, Lynn Gargan, Angela Price, Frederick H Sklar, Bruno Braga, Bradley E. Weprin, Dale M. Swift, Ramzi Abdulrahman, Chuxiong Ding, Tu Dan, Anh Le
Publikováno v:
Practical Radiation Oncology. 10:e485-e494
Conventional radiation therapy (RT) to pediatric brain tumors exposes a large volume of normal brain to unwarranted radiation causing late toxicity. We hypothesized that in well demarcated pediatric tumors lacking microscopic extensions, fractionated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ceaf3aab870e18aee1fc1f0aa7aa96
https://doi.org/10.1016/j.prro.2020.03.013
https://doi.org/10.1016/j.prro.2020.03.013
Autor:
Lisanne C Verbruggen, Renée L. Mulder, L. C. M. Kremer, Gregory T. Armstrong, Helena J H van der Pal, Geert O. Janssens, Cécile M. Ronckers, Roderick Skinner, Melissa M. Hudson, Daniel C. Bowers, Eelco W. Hoving
Publikováno v:
Journal of neuro-oncology, 147(2), 417-425. Kluwer Academic Publishers
Introduction: Childhood, adolescent and young adult (CAYA) cancer survivors treated with cranial radiotherapy are at risk for developing subsequent meningiomas. There is insufficient evidence concerning the benefits and harms of screening for subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9438ae54555d6e0771c451d950c317
https://doi.org/10.1007/s11060-020-03436-5
https://doi.org/10.1007/s11060-020-03436-5
Autor:
Torsten Pietsch, Miriam Elbracht, Sebastian M. Waszak, Florian Kraft, Felix Sahm, Daniel C. Bowers, Martin Mynarek, Udo Kontny, Jan O. Korbel, Pascale Varlet, Matthias Begemann, Stefan M. Pfister, Laurence Brugières, Cordula Knopp, Olga Moser, Paul A. Northcott, Murali Chintagumpala, Thomas Eggermann, Ingo Kurth, Tanvi Sharma, Stefan Rutkowski, Natalie Jäger, Amar Gajjar, Giles W. Robinson, Léa Guerrini-Rousseau
Publikováno v:
Journal of Clinical Oncology
PURPOSE The identification of a heritable tumor predisposition often leads to changes in management and increased surveillance of individuals who are at risk; however, for many rare entities, our knowledge of heritable predisposition is incomplete. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b46665a285d6cae89bc80014bec7170
https://doi.org/10.1200/jco.19.00577
https://doi.org/10.1200/jco.19.00577