Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Daniel C Berry"'
Autor:
Sunhye Shin, Yiyu Pang, Jooman Park, Lifeng Liu, Brandon E Lukas, Seung Hyeon Kim, Ki-Wook Kim, Pingwen Xu, Daniel C Berry, Yuwei Jiang
Publikováno v:
eLife, Vol 9 (2020)
Adipocytes arise from distinct progenitor populations during developmental and adult stages but little is known about how developmental progenitors differ from adult progenitors. Here, we investigate the role of platelet-derived growth factor recepto
Externí odkaz:
https://doaj.org/article/1ee90da64bd24eaa86a8eae0fd615b3c
Publikováno v:
eLife, Vol 6 (2017)
Beige/brite adipocytes are induced within white adipose tissues (WAT) and, when activated, consume glucose and fatty acids to produce heat. Classically, two stimuli have been used to trigger a beiging response: cold temperatures and β3-adrenergic re
Externí odkaz:
https://doaj.org/article/aa8f0d41cc994f5faaa039052c2b7900
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sex steroids modulate the distribution of mammalian white adipose tissues. Moreover, WAT remodeling requires adipocyte progenitor cells. Nevertheless, the sex-dependent mechanisms regulating adipocyte progenitors remain undetermined. Here, w
Externí odkaz:
https://doaj.org/article/f81eb867a4b64298ae9c09189becdd3a
Autor:
Abigail M. Benvie, Daniel C. Berry
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102028- (2024)
Objective: Platelet Derived Growth Factor Receptor Beta (Pdgfrβ) suppresses the formation of cold temperature-induced beige adipocytes in aged mammals. We aimed to determine if deleting Pdgfrβ in aged mice could rejuvenate metabolically active beig
Externí odkaz:
https://doaj.org/article/399b9fddecac45cc9d7fcc2b7bb30a7a
Autor:
Derek Lee, Abigail M. Benvie, Benjamin M. Steiner, Nikolai J. Kolba, Josie G. Ford, Sean M. McCabe, Yuwei Jiang, Daniel C. Berry
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114169- (2024)
Summary: Sympathetic innervation of brown adipose tissue (BAT) controls mammalian adaptative thermogenesis. However, the cellular and molecular underpinnings contributing to BAT innervation remain poorly defined. Here, we show that smooth muscle cell
Externí odkaz:
https://doaj.org/article/c4ef0a4c0b46429b950895b44c04081e
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108682- (2024)
Summary: White adipose tissue (WAT) development and adult homeostasis rely on distinct adipocyte progenitor cells (APCs). While adult APCs are defined early during embryogenesis and generate adipocytes after WAT organogenesis, the mechanisms underlyi
Externí odkaz:
https://doaj.org/article/4c9f76ae2a1f4fc7963194098d830722
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Thermogenic beige fat can reduce fat mass and improve metabolic health, yet the ability to form beige fat rapidly declines with age. Here, the authors show that targeting the age-related ramping of Pdgfrβ signalling restores the ageing adipose tissu
Externí odkaz:
https://doaj.org/article/45af6c1631654c93938e123edfa18ff1
Autor:
Seoyeon Lee, Abigail M. Benvie, Hui Gyu Park, Roman Spektor, Blaine Harlan, J. Thomas Brenna, Daniel C. Berry, Paul D. Soloway
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Adipocyte beiging is a thermogenic response to cold exposure and b3-adrenergic receptor agonists, which exert their effects by distinct and common molecular mechanisms that control chromatin accessibility and lipid metabolism.
Externí odkaz:
https://doaj.org/article/9ecacc2372344959befed191d75666c6
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The ability to generate thermogenic fat could be a targeted therapy to thwart obesity and improve metabolic health. Brown and beige adipocytes are two types of thermogenic fat cells that regulate energy balance. Both adipocytes share common morpholog
Externí odkaz:
https://doaj.org/article/0abf8fae86974319bbfe4c61c526f6ed
Autor:
Benjamin M. Steiner, Daniel C. Berry
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity and its’ associated metabolic diseases such as type 2 diabetes and cardiometabolic disorders are significant health problems confronting many countries. A major driver for developing obesity and metabolic dysfunction is the uncontrolled exp
Externí odkaz:
https://doaj.org/article/cbd137b9aab845d6aeee4dc2a4ec72e2