Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Byrom"'
Autor:
Alexandre Calon, Elisa Espinet, Sergio Palomo-Ponce, Daniele Tauriello, Mar Iglesias, María Céspedes, Marta Sevillano, Cristina Nadal, Peter Jung, Xiang Zhang, Daniel Byrom, Antoni Riera, David Rossell, Ramón Mangues, Joan Massague, Elena Sancho, Eduard Batlle
Publikováno v:
Bio-Protocol, Vol 4, Iss 9 (2014)
Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 accum
Externí odkaz:
https://doaj.org/article/6cc39bbe3e3440febc0c004e15972986
Autor:
Xavier Hernando-Momblona, Elisa I. Rivas, Antonio Berenguer-Llergo, Daniel Byrom, Adrià Cañellas, Antoni Riera, Angel R. Nebreda, Mar Iglesias, Sergio Palomo-Ponce, Sales Ibiza, Daniele V.F. Tauriello, Diana Stork, Marta Sevillano, Jordi Badia-Ramentol, Alexandre Calon, Joan A. Matarin, Camille Stephan-Otto Attolini, Eduard Batlle
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Most patients with colorectal cancer die as a result of the disease spreading to other organs. However, no prevalent mutations have been associated with metastatic colorectal cancers1,2. Instead, particular features of the tumour microenvironment, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c9bf72f6bd377a9963ca2929c363f2
http://hdl.handle.net/2445/120345
http://hdl.handle.net/2445/120345
Autor:
Xavier Verdaguer, Antoni Riera, Hester Zijlstra, Célia Fonseca Guerra, F. Matthias Bickelhaupt, Abel de Cózar, Daniel Byrom, Thierry León
Publikováno v:
Journal of the American Chemical Society, 2013(135), 4483-4491. American Chemical Society
Journal of the American Chemical Society, 135, 11, pp. 4483-4491
Journal of the American Chemical Society, 135, 4483-4491
Zijlstra, H, Léon, T, de Cózar, A, Fonseca Guerra, C, Byrom, D, Riera, A, Verdaguer, X & Bickelhaupt, F M 2013, ' Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies ', Journal of the American Chemical Society, vol. 2013, no. 135, pp. 4483-4491 . https://doi.org/10.1021/ja400208t
Journal of the American Chemical Society, 135, 11, pp. 4483-4491
Journal of the American Chemical Society, 135, 4483-4491
Zijlstra, H, Léon, T, de Cózar, A, Fonseca Guerra, C, Byrom, D, Riera, A, Verdaguer, X & Bickelhaupt, F M 2013, ' Stereodivergent SN2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies ', Journal of the American Chemical Society, vol. 2013, no. 135, pp. 4483-4491 . https://doi.org/10.1021/ja400208t
The stereodivergent ring-opening of 2-phenyl oxazaphospholidines with alkyl lithium reagents is reported. N-H oxazaphospholidines derived from both (+)-cis-1-amino-2-indanol and (-)-norephedrine provide inversion products in a highly stereoselective
Autor:
Antoni Riera, Elena Sancho, Sergio Palomo-Ponce, Enza Lonardo, Carme Cortina, Sébastien Tosi, Daniel Byrom, Xavier Hernando-Momblona, Alexandre Calon, Antonio Berenguer-Llergo, Camille Stephan-Otto Attolini, Daniele V.F. Tauriello, Mar Iglesias, David Rossell, Eduard Batlle, Marta Sevillano, Carles Barceló, Clara Morral, Elisa Espinet
Recent molecular classifications of colorectal cancer (CRC) based on global gene expression profiles have defined subtypes displaying resistance to therapy and poor prognosis. Upon evaluation of these classification systems, we discovered that their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c454cf2108bbaa5e0edb8625d464105
http://hdl.handle.net/10230/23362
http://hdl.handle.net/10230/23362
Autor:
Daniel Byrom, Cristina Nadal, Antoni Riera, Daniele V.F. Tauriello, Ramon Mangues, María Virtudes Céspedes, Peter Jung, Sergio Palomo-Ponce, Elisa Espinet, Elena Sancho, Marta Sevillano, David Rossell, Alexandre Calon, Joan Massagué, Eduard Batlle, Xiang Zhang, Mar Iglesias
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
We sought to understand the mechanisms behind the potent effect of stromal TGF-beta program on the capacity of colorectal cancer (CRC) cells to initiate metastasis. We discovered that mice subcutaneous tumors and metastases generated in the context o
Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
Autor:
Antoni Riera, Daniele V.F. Tauriello, Daniel Byrom, Elena Sancho, Sergio Palomo-Ponce, David Rossell, Peter Jung, María Virtudes Céspedes, Alexandre Calon, Marta Sevillano, Ramon Mangues, Joan Massagué, Eduard Batlle, Cristina Nadal, Xiang Zhang, Elisa Espinet, Mar Iglesias
Publikováno v:
Cancer Cell. (5):571-584
SummaryA large proportion of colorectal cancers (CRCs) display mutational inactivation of the TGF-β pathway, yet, paradoxically, they are characterized by elevated TGF-β production. Here, we unveil a prometastatic program induced by TGF-β in the m