Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Daniel Bushnell"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88400 (2014)
The renal stroma is an embryonic cell population located in the cortex that provides a structural framework as well as a source of endothelial progenitors for the developing kidney. The exact role of the renal stroma in normal kidney development hasn
Externí odkaz:
https://doaj.org/article/46e5738733c9492e9ac43b0968a03c13
Autor:
Sunder Sims-Lucas, Caitlin Schaefer, Daniel Bushnell, Jacqueline Ho, Alison Logar, Edward Prochownik, George Gittes, Carlton M Bates
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65993 (2013)
The renal endothelium has been debated as arising from resident hemangioblast precursors that transdifferentiate from the nephrogenic mesenchyme (vasculogenesis) and/or from invading vessels (angiogenesis). While the Foxd1-positive renal cortical str
Externí odkaz:
https://doaj.org/article/af53d293bc5d4def9c407868aea1ca7e
Autor:
Carlton M. Bates, Jacqueline Ho, Sunder Sims-Lucas, Débora M. Cerqueira, Brynn E Shrom, Melissa J Anslow, Daniel Bushnell, Andrew J. Bodnar
Publikováno v:
Pediatric research
BACKGROUND: Vesicoureteral reflux (VUR), backflow of urine into the kidney, is associated with urinary tract infections and chronic kidney disease. Integrity of the vesicoureteral junction (VUJ), where reflux occurs, is determined largely by proper i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28d59c36bfc29d9b0ef9b73ec83ed65
https://doi.org/10.1038/s41390-020-0788-7
https://doi.org/10.1038/s41390-020-0788-7
Publikováno v:
Am J Pathol
Keratinocyte growth factor (KGF) improves cyclophosphamide-induced bladder injury. To understand the mechanisms, we subcutaneously administered KGF to mice 24 hours before i.p. cyclophosphamide administration, followed by histologic assays and immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d898be34b757c510c40935a9ce457e
https://doi.org/10.1016/j.ajpath.2019.09.015
https://doi.org/10.1016/j.ajpath.2019.09.015
Autor:
Sridhar T. Narla, Mehdi Nouraie, Daniel Bushnell, Timothy W. Hand, Justin T. Tometich, Carlton M. Bates, Caitlin Schaefer
Publikováno v:
Am J Pathol
Cyclophosphamide may cause hemorrhagic cystitis and eventually bladder urothelial cancer. Genetic determinants for poor outcomes are unknown. We assessed actions of fibroblast growth factor receptor (FGFR) 2 in urothelium after cyclophosphamide expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fc602ab6117d01aeb7bde50f170dc8
https://pubmed.ncbi.nlm.nih.gov/33385344
https://pubmed.ncbi.nlm.nih.gov/33385344
Autor:
Mary E. Taglienti, Bradley K. Yoder, Jordan A. Kreidberg, Caitlin Schaefer, Carlton M. Bates, Pawan Puri, Daniel Bushnell
Publikováno v:
The American Journal of Pathology. 188:84-94
Ectopic cAMP signaling is pathologic in polycystic kidney disease; however, its spatiotemporal actions are unclear. We characterized the expression of phosphorylated Creb (p-Creb), a target and mediator of cAMP signaling, in developing and cystic kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c943c110d8d9132635b4d669a7fd03b8
https://doi.org/10.1016/j.ajpath.2017.09.015
https://doi.org/10.1016/j.ajpath.2017.09.015
Autor:
Elina Mukherjee, Benjamin D. Humphreys, Daniel Bushnell, Rafael Kramann, Katherine Maringer, Emily Papke, Jacqueline Ho, Sunder Sims-Lucas, Caitlin Schaefer, Carlton M. Bates
Publikováno v:
American Journal of Physiology-Renal Physiology. 313:F611-F620
Kidneys are highly vascularized and contain many distinct vascular beds. However, the origins of renal endothelial cells and roles of the developing endothelia in the formation of the kidney are unclear. We have shown that the Foxd1-positive renal st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d2b4603650169df1fe436c4c8bcc5b
https://doi.org/10.1152/ajprenal.00136.2017
https://doi.org/10.1152/ajprenal.00136.2017
Autor:
Caitlin Schaefer, Deepti Narla, Carlton M. Bates, Pawan Puri, Daniel Bushnell, Stacey B Slagle
Publikováno v:
Pediatric research
Background Fibroblast growth factor receptor 2 (Fgfr2) deletion from murine peri-Wolffian duct stroma (ST) results in aberrant ureteric bud induction, abnormal ureteral insertion into the bladder, and high rates of vesicoureteral reflux (VUR). It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa52df0ce7638e21ce0808876d7fb3
https://doi.org/10.1038/pr.2017.175
https://doi.org/10.1038/pr.2017.175
Autor:
Dennis Kostka, Jiao Liu, Shelby L. Hemker, Andrew Clugston, Carlton M. Bates, Kasey R Cargill, Andrew J. Bodnar, Anjana Murali, Sunder Sims-Lucas, Jacqueline Ho, Zubaida Saifudeen, Eric S. Goetzman, Elina Mukherjee, Daniel Bushnell
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Nephron progenitors, the cell population that give rise to the functional unit of the kidney, are metabolically active and self-renew under glycolytic conditions. A switch from glycolysis to mitochondrial respiration drives these cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e8a72c8707b21c003c1efc2cf5ba0c
https://europepmc.org/articles/PMC6622426/
https://europepmc.org/articles/PMC6622426/
Autor:
Russ P. Carstens, Benjamin Cieply, Daniel Bushnell, Sunder Sims-Lucas, Carlton M. Bates, Juw Won Park, Thomas W. Bebee, Yi Xing
Publikováno v:
Developmental Dynamics
Background: Abnormalities in ureteric bud (UB) branching morphogenesis lead to congenital anomalies of the kidney and reduced nephron numbers associated with chronic kidney disease (CKD) and hypertension. Previous studies showed that the epithelial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7782df52509419c17d5f54cbfadf7f
https://doi.org/10.1002/dvdy.24431
https://doi.org/10.1002/dvdy.24431