Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daniel Bose"'
Autor:
Johnathan Cooper-Knock, Sai Zhang, Kevin P. Kenna, Tobias Moll, John P. Franklin, Samantha Allen, Helia Ghahremani Nezhad, Alfredo Iacoangeli, Nancy Y. Yacovzada, Chen Eitan, Eran Hornstein, Eran Ehilak, Petra Celadova, Daniel Bose, Sali Farhan, Simon Fishilevich, Doron Lancet, Karen E. Morrison, Christopher E. Shaw, Ammar Al-Chalabi, Jan H. Veldink, Janine Kirby, Michael P. Snyder, Pamela J. Shaw, Ian Blair, Naomi Wray, Matthew Kiernan, Miguel Mitne Neto, Adriano Chio, Ruben Cauchi, Wim Robberecht, Philip van Damme, Phillippe Corcia, Phillipe Couratier, Orla Hardiman, Russel McLaughlin, Marc Gotkine, Vivan Drory, Nicola Ticozzi, Vincenzo Silani, Jan Veldink, Leonard van den Berg, Mamede de Carvalho, Jesus Mora Pardina, Monica Povedano, Peter Andersen, Markus Wber, Nazli Başak, Christopher Shaw, Pamela Shaw, Karen Morrison, John Landers, Jonathan Glass
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108456- (2020)
Summary: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vi
Externí odkaz:
https://doaj.org/article/7fac5ebf332545088de18b27ea1f88df
Autor:
Laura Harrison, Daniel Bose
Publikováno v:
Development. 149
Enhancers confer precise spatiotemporal patterns of gene expression in response to developmental and environmental stimuli. Over the last decade, the transcription of enhancer RNAs (eRNAs) – nascent RNAs transcribed from active enhancers – has em
Autor:
Petra Celadova, Allison N. Catizone, Gizem Karsli Uzunbas, Sylvia Kuang, Daniel Bose, Morgan A. Sammons
Publikováno v:
Nucleic Acids Research
The master tumor suppressor p53 controls transcription of a wide-ranging gene network involved in apoptosis, cell cycle arrest, DNA damage repair, and senescence. Recent studies revealed pervasive binding of p53 to cis-regulatory elements (CREs), whi
Autor:
Johnathan Cooper-Knock, Sai Zhang, Kevin P. Kenna, Tobias Moll, John Franklin, Samantha Allen, Helia Ghahremani Nezhad, Nancy S. Yacovzada, Chen Eitan, Eran Hornstein, Eran Ehilak, Petra Celadova, Daniel Bose, Sali MK Farhan, Simon Fishilevich, Doron Lancet, Karen E. Morrison, Chris Shaw, Ammar Al-Chalabi, Project MinE ALS Sequencing Consortium, Jan H. Veldink, Janine Kirby, Michael P. Snyder, Pamela J. Shaw
Publikováno v:
SSRN Electronic Journal.
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organise membrane lipid rafts (MLR) important for cell signalling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo. Genom
Autor:
Sylvia Kuang, Petra Celadova, Morgan A. Sammons, Daniel Bose, Gizem Karsli Uzunbas, Allison N. Catizone
The master tumor suppressor p53 controls transcription of a wide-ranging gene network involved in apoptosis, cell cycle arrest, DNA damage repair, and senescence. Recent studies revealed pervasive binding of p53 to cis-regulatory elements (CRE), whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab74ea0c51c29190ead85fd85c57f50a
https://doi.org/10.1101/761387
https://doi.org/10.1101/761387
Autor:
Daniel Bose, Shelley L. Berger
Publikováno v:
RNA biology. 14(12)
Enhancers are cis- regulatory genetic elements crucial for controlling temporal and cell-type specific patterns of gene expression. Active enhancers generate bi-directional non-coding RNA transcripts called enhancer RNAs (eRNAs). eRNAs are important
Autor:
Shelley L. Berger, Greg Donahue, Daniel Bose, Danny Reinberg, Ramin Shiekhattar, Roberto Bonasio
CBP/p300 are transcription co-activators whose binding is a signature of enhancers, cis-regulatory elements that control patterns of gene expression in multicellular organisms. Active enhancers produce bi-directional enhancer RNAs (eRNAs) and display
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1a8b6de9b23f8628602e72effa4ab1
https://europepmc.org/articles/PMC5325706/
https://europepmc.org/articles/PMC5325706/
Autor:
Marta, Sawicka, Paulina H, Wanrooij, Vidya C, Darbari, Elias, Tannous, Sarem, Hailemariam, Daniel, Bose, Alena V, Makarova, Peter M, Burgers, Xiaodong, Zhang
Publikováno v:
The Journal of Biological Chemistry
The phosphatidylinositol 3-kinase-related protein kinases are key regulators controlling a wide range of cellular events. The yeast Tel1 and Mec1·Ddc2 complex (ATM and ATR-ATRIP in humans) play pivotal roles in DNA replication, DNA damage signaling,
Autor:
Beatriz Cámara, Milija Jovanovic, Martin Buck, Sivaramesh Wigneshweraraj, Simone C. Wiesler, Patricia C. Burrows, Daniel Bose, Robert O. J. Weinzierl, Xiaodong Zhang
Publikováno v:
The Journal of Biological Chemistry
Transcription, the synthesis of RNA from a DNA template, is performed by multisubunit RNA polymerases (RNAPs) in all cellular organisms. The bridge helix (BH) is a distinct feature of all multisubunit RNAPs and makes direct interactions with several
Publikováno v:
FEMS Microbiology Reviews. 34:611-627
Gene transcription is a fundamental cellular process carried out by RNA polymerase (RNAP) enzymes and is highly regulated through the action of gene regulatory complexes. Important mechanistic insights have been gained from structural studies on mult