Zobrazeno 1 - 10
of 707
pro vyhledávání: '"Daniel Birnbaum"'
Autor:
François Bertucci, Florence Lerebours, Michele Ceccarelli, Arnaud Guille, Najeeb Syed, Pascal Finetti, José Adélaïde, Steven Van Laere, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Emilie Mamessier, Céline Callens, Davide Bedognetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Inflammatory breast cancer (IBC) is the most pro-metastatic form of BC. Better understanding of its enigmatic pathophysiology is crucial. We report here the largest whole-exome sequencing (WES) study of clinical IBC samples. Metho
Externí odkaz:
https://doaj.org/article/d411209f682649f3b4011eb089a7cbba
Autor:
Alice Mogenet, Pascal Finetti, Emilie Denicolai, Laurent Greillier, Pascaline Boudou-Rouquette, François Goldwasser, Gwenael Lumet, Michele Ceccarelli, Daniel Birnbaum, Davide Bedognetti, Emilie Mamessier, Fabrice Barlesi, François Bertucci, Pascale Tomasini
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Anti-PD1/PDL1 immune checkpoint inhibitors (ICI) transformed the prognosis of patients with advanced non-small cell lung cancer (NSCLC). However, the response rate remains disappointing and toxicity may be life-threatening, making
Externí odkaz:
https://doaj.org/article/67108f51d6d841e88d4d580890ae1436
Autor:
Nathalie Cervera, Arnaud Guille, José Adélaïde, Marie‐Anne Hospital, Sylvain Garciaz, Marie‐Joelle Mozziconacci, Norbert Vey, Véronique Gelsi‐Boyer, Daniel Birnbaum
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 450-453 (2023)
Abstract Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and
Externí odkaz:
https://doaj.org/article/d6312bdd72cb46629c506d098c5d8cc2
Autor:
Laurys Boudin, A de Nonneville, Pascal Finetti, Léna Mescam, A Le Cesne, Antoine Italiano, Jean-Yves Blay, Daniel Birnbaum, Emilie Mamessier, François Bertucci
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Soft tissue sarcomas (STS) are heterogeneous and pro-metastatic tumors. Identification of accurate prognostic factors and novel therapeutic targets are crucial. CSPG4 is a cell surface proteoglycan with oncogenic functions. It rec
Externí odkaz:
https://doaj.org/article/f6527691660149788a4e90bf8c5daef5
Autor:
Anaïs Aulas, Maria Lucia Liberatoscioli, Pascal Finetti, Olivier Cabaud, David J. Birnbaum, Lucas Usclade, Daniel Birnbaum, François Bertucci, Emilie Mamessier
Publikováno v:
Cancer Communications, Vol 42, Iss 8, Pp 793-797 (2022)
Externí odkaz:
https://doaj.org/article/491aad5dabbe4e17a539f8d05f24f971
Autor:
Carolina Velazquez, Esin Orhan, Imene Tabet, Lise Fenou, Béatrice Orsetti, José Adélaïde, Arnaud Guille, Simon Thézénas, Evelyne Crapez, Pierre-Emmanuel Colombo, Max Chaffanet, Daniel Birnbaum, Claude Sardet, William Jacot, Charles Theillet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAbout 15% of Triple-Negative-Breast-Cancer (TNBC) present silencing of the BRCA1 promoter methylation and are assumed to be Homologous Recombination Deficient (HRD). BRCA1-methylated (BRCA1-Me) TNBC could, thus, be eligible to treatment bas
Externí odkaz:
https://doaj.org/article/e04a4c983fe14d5c8fffd7f0ddb98082
Autor:
Violette Azzoni, Julien Wicinski, Manon Macario, Martin Castagné, Pascal Finetti, Katerina Ambrosova, Célia D. Rouault, Arnaud Sergé, Anne Farina, Emilie Agavnian, Sergiu Coslet, Emmanuelle Josselin, Arnaud Guille, José Adelaide, Emmanouil Zacharioudakis, Rémy Castellano, Francois Bertucci, Daniel Birnbaum, Raphael Rodriguez, Emmanuelle Charafe-Jauffret, Christophe Ginestier
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-15 (2022)
Abstract Replication stress (RS) has a pivotal role in tumor initiation, progression, or therapeutic resistance. In this study, we depicted the mechanism of breast cancer stem cells’ (bCSCs) response to RS and its clinical implication. We demonstra
Externí odkaz:
https://doaj.org/article/41f1ef2e00194644a397b32092889d81
Autor:
Charlotte Rypens, François Bertucci, Pascal Finetti, Fredika Robertson, Sandra V. Fernandez, Naoto Ueno, Wendy A. Woodward, Kenneth Van Golen, Peter Vermeulen, Luc Dirix, Patrice Viens, Daniel Birnbaum, Gayathri R. Devi, Massimo Cristofanilli, Steven Van Laere
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Inflammatory breast cancer (IBC) is an aggressive disease for which the spectrum of preclinical models was rather limited in the past. More recently, novel cell lines and xenografts have been developed. This study evaluates the transcriptome
Externí odkaz:
https://doaj.org/article/5f7d6093dd1c479cb755cd0da5f6d23f
Autor:
Sandra Udu-Ituma, José Adélaïde, Thi Khanh Le, Kenneth Omabe, Pascal Finetti, Clément Paris, Arnaud Guille, François Bertucci, Daniel Birnbaum, Palma Rocchi, Max Chaffanet
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1930 (2023)
The luminal B molecular subtype of breast cancers (BC) accounts for more than a third of BCs and is associated with aggressive clinical behavior and poor prognosis. The use of endocrine therapy in BC treatment has significantly contributed to the dec
Externí odkaz:
https://doaj.org/article/6ce250a765aa49609d7037ef5f6e3b22
Autor:
Alexandre deNonneville, Sébastien Salas, François Bertucci, Alexander P Sobinoff, José Adélaïde, Arnaud Guille, Pascal Finetti, Jane R Noble, Dimitri Churikov, Max Chaffanet, Elise Lavit, Hilda A Pickett, Corinne Bouvier, Daniel Birnbaum, Roger R Reddel, Vincent Géli
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp n/a-n/a (2022)
Abstract In some types of cancer, telomere length is maintained by the alternative lengthening of telomeres (ALT) mechanism. In many ALT cancers, the α‐thalassemia/mental retardation syndrome X‐linked (ATRX) gene is mutated leading to the conclu
Externí odkaz:
https://doaj.org/article/948680b27447452fa822018d83b4b8e5