Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel Billadeau"'
Autor:
Li Ding, Kaely Roeck, Cheng Zhang, Brooke Zidek, Esther Rodman, Yasmin Hernandez-Barco, Jin-San Zhang, William Bamlet, Ann Oberg, Lizhi Zhang, Nabeel Bardeesy, Hu Li, Daniel Billadeau
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Glycogen synthase kinase-3β (GSK-3β) is a downstream target of oncogenic KRas and can accumulate in the nucleus in pancreatic ductal adenocarcinoma (PDA). To determine the interplay between oncogenic KRas and nuclear GSK-3β in PDA development, we
Externí odkaz:
https://doaj.org/article/00bbe76b71c64767bc4926e942ff9aa5
Autor:
Taylor Weiskittel, Joseph McDermott, Daniel Billadeau, Hu Li, Anwaar Saeed, Devalingam Mahalingam, Solmaz Sahebjam, Pamela Munster, Ludimila Cavalcante, Frank J. Giles, Andrew Mazar, Benedito Carneiro
Publikováno v:
Cancer Research. 83:CT222-CT222
9-ING-41 (elraglusib) is a potent and selective GSK-3 inhibitor that has shown anti-tumor activity in patient-derived xenograft models and phase1/2 clinical studies in patients (pts) with advanced solid tumors. Preclinical studies have demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::482a351ac875cfd407e70f68b2fd0a84
https://doi.org/10.1158/1538-7445.am2023-ct222
https://doi.org/10.1158/1538-7445.am2023-ct222
Autor:
Nagaja Capitani, Anna Onnis, FRANCESCA FINETTI, Chiara Cassioli, Alessandro Plebani, Jlenia Brunetti, Arianna Troilo, Sofia D'Elios, Manuela Baronio, Luisa Gazzurrelli, Daniel Billadeau, Mario D'Elios, Vassilios Lougaris, Cosima Baldari
Ciliogenesis proteins orchestrate vesicular trafficking pathways that regulate immune synapse (IS) assembly in the non-ciliated T cells. We hypothesized that ciliogenesis-related genes might be disease candidates for common variable immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea1308c24ccd8bc4983563421987a503
https://doi.org/10.21203/rs.3.rs-86351/v1
https://doi.org/10.21203/rs.3.rs-86351/v1
Publikováno v:
Cancer Research. 79:3723-3723
Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States and continues to be hindered with limited treatment options. One of the current therapeutic regimens for pancreatic cancer often include the nucleoside analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b346f169fba060f917b01ac95f2dfecb
https://doi.org/10.1158/1538-7445.am2019-3723
https://doi.org/10.1158/1538-7445.am2019-3723
Autor:
Timothy Gomez, Daniel Billadeau
Publikováno v:
AfCS-Nature Molecule Pages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f88e383daf6db63746ca3864acea708
https://doi.org/10.1038/mp.a004133.01
https://doi.org/10.1038/mp.a004133.01
Autor:
Karen Hedin, Adebowale Bamidele, Kimberly Kremer, Petra Hirsova, Gregory Gores, Daniel Billadeau
Publikováno v:
The Journal of Immunology. 194:49.13-49.13
IQGAP1 is a ubiquitous, cytoskeletal-interacting scaffold protein frequently overexpressed in cancer. CXCR4 is a chemokine receptor that signals upon binding stromal cell-derived factor 1 (SDF-1, CXCL12). CXCR4 regulates lymphocyte migration and deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db910006a8bfdf40bdde21df87a60251
https://doi.org/10.4049/jimmunol.194.supp.49.13
https://doi.org/10.4049/jimmunol.194.supp.49.13
Autor:
Douglas Osborne, Daniel Billadeau
Publikováno v:
The Journal of Immunology. 192:58.2-58.2
A key component in T cell activation is the endosomal recycling of receptors to the cell surface allowing for continual integration of signaling and antigen recognition. Multiple early endosomal associated proteins have been found to interact with T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7255e2f43a6cab55709e8c92a515593f
https://doi.org/10.4049/jimmunol.192.supp.58.2
https://doi.org/10.4049/jimmunol.192.supp.58.2
Autor:
Neil E. Kay, Traci Leong, Robert A. Kyle, Philip Greipp, Daniel Billadeau, Brian Van Ness, Nancy Bone, Martin M. Oken
Publikováno v:
Blood. 90(1)
Recent analyses of circulating blood B cells in myeloma have generated controversy concerning the exact levels of these cells and whether they may represent circulating clonal tumor B cells. Previous reports suggested that CD19+ B cells are markedly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123da6ec04d67c02188dc23a490f48bd
https://pubmed.ncbi.nlm.nih.gov/9207470
https://pubmed.ncbi.nlm.nih.gov/9207470
Publikováno v:
Experts@Minnesota
Multiple myeloma (MM) is a late-stage B-cell cancer with an unknown etiology. Activating mutations of the N-ras and K-ras oncogenes occur with a high frequency in myeloma and, therefore, may play a role in the pathogenesis of the disease. To study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ee2dfe43dc811213a0593813742dff8f
https://pubmed.ncbi.nlm.nih.gov/7627974
https://pubmed.ncbi.nlm.nih.gov/7627974
Publikováno v:
The Journal of Immunology. 184:138.15-138.15
NKG2D is expressed on cytotoxic lymphocytes and is an important immunosurveillance receptor that recognizes stress ligands such as MICA on tumor cells or virally infected cells. Unlike traditional immune activating receptors, NKG2D couples to the non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7026ff21bd466c9bb829ac1f4ddcbc
https://doi.org/10.4049/jimmunol.184.supp.138.15
https://doi.org/10.4049/jimmunol.184.supp.138.15