Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Daniel Bilbao"'
Autor:
Hidehiro Itonaga, Adnan K. Mookhtiar, Sarah M. Greenblatt, Fan Liu, Concepcion Martinez, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma C. Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas, Luca Tottone, Tulasigeri Totiger, Terrence Bradley, Justin Taylor, Stephan Schürer, Stephen D. Nimer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract An important epigenetic component of tyrosine kinase signaling is the phosphorylation of histones, and epigenetic readers, writers, and erasers. Phosphorylation of protein arginine methyltransferases (PRMTs), have been shown to enhance and i
Externí odkaz:
https://doaj.org/article/bb03cbb7b5b1413899e42167143b1e64
Autor:
Md Obaidul Islam, Krishnapriya Thangaretnam, Heng Lu, Dunfa Peng, Mohammed Soutto, Wael El-Rifai, Silvia Giordano, Yuguang Ban, Xi Chen, Daniel Bilbao, Alejandro V. Villarino, Stephan Schürer, Peter J. Hosein, Zheng Chen
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 286-300 (2023)
Esophageal adenocarcinoma (EAC) patients have poor clinical outcomes, with an overall 5-year survival rate of 20%. Smoking is a significant risk factor for EAC. The role of WEE1, a nuclear kinase that negatively regulates the cell cycle in normal con
Externí odkaz:
https://doaj.org/article/84c70702c03349cca06fdc726ba267ef
Autor:
Daniel Bilbao Moreno, Unai Ferrer Uriarte, Jose Javier Viñals Abelan, Gonzalo Guerra Franco, Eloy Irigoyen Gordo, Itziar Cabanes Axpe
Publikováno v:
Revista Iberoamericana de Automática e Informática Industrial RIAI, Vol 20, Iss 3, Pp 269-280 (2023)
Con objeto de realizar tareas de servicio en órbita de manera autónoma y sin necesidad de personal humano, este trabajo presenta el desarrollo de un sistema robótico de auto-acoplamiento basado en cámaras y marcadores visuales que permiten facili
Externí odkaz:
https://doaj.org/article/89c38889d2f44b72b796f5e80177fc52
Autor:
Gloria Mas, Na Man, Yuichiro Nakata, Concepcion Martinez-Caja, Daniel Karl, Felipe Beckedorff, Francesco Tamiro, Chuan Chen, Stephanie Duffort, Hidehiro Itonaga, Adnan K. Mookhtiar, Kranthi Kunkalla, Alfredo M. Valencia, Clayton K. Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Lluis Morey, Daniel Bilbao, Stephen D. Nimer
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
During emergency hematopoiesis, hematopoietic stem cells (HSCs) rapidly proliferate to produce myeloid and lymphoid effector cells, a response that is critical against infection or tissue injury. If unresolved, this process leads to sustained inflamm
Externí odkaz:
https://doaj.org/article/2118c0f847304f59b6180d6c918e01a4
Autor:
Nina Nguyen, Sana Chaudhry, Tulasigeri M. Totiger, Robert Diaz, Evan Roberts, Skye Montoya, Gabriel Pardo, Alejandro Pardo, Jumana Afaghani, Maurizio Affer, Jacob Jahn, Terrence Bradley, Francesco Maura, Dickran Kazandjian, Daniel Bilbao, Jennifer Chapman, Ola Landgren, James Hoffman, Justin Taylor
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-7 (2022)
Abstract Patients with multiple myeloma-bearing translocation t(11;14) have recently been shown to benefit from the apoptosis-inducing drug venetoclax; however, the drug lacks FDA approval in multiple myeloma thus far due to a potential safety signal
Externí odkaz:
https://doaj.org/article/564ff253130c483889cff4cc28a34947
Autor:
John P. Brabson, Tiffany Leesang, Yoon Sing Yap, Jingjing Wang, Minh Q. Lam, Byron Fang, Igor Dolgalev, Daniela A. Barbieri, Victoria Strippoli, Carolina P. Bañuelos, Sofia Mohammad, Peter Lyon, Sana Chaudhry, Dane Donich, Anna Swirski, Evan Roberts, Ivelisse Diaz, Daniel Karl, Helena Gomes Dos Santos, Ramin Shiekhattar, Benjamin G. Neel, Stephen D. Nimer, Ramiro E. Verdun, Daniel Bilbao, Maria E. Figueroa, Luisa Cimmino
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112027- (2023)
Summary: TET2 haploinsufficiency is a driving event in myeloid cancers and is associated with a worse prognosis in patients with acute myeloid leukemia (AML). Enhancing residual TET2 activity using vitamin C increases oxidized 5-methylcytosine (mC) f
Externí odkaz:
https://doaj.org/article/5e49692c1c5545df90f0bdb82844b32f
Autor:
Jessica Hersh, Yu-Ping Yang, Evan Roberts, Daniel Bilbao, Wensi Tao, Alan Pollack, Sylvia Daunert, Sapna K. Deo
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1976 (2023)
In vivo imaging has enabled impressive advances in biological research, both preclinical and clinical, and researchers have an arsenal of imaging methods available. Bioluminescence imaging is an advantageous method for in vivo studies that allows for
Externí odkaz:
https://doaj.org/article/f90e348bccdf47f78db1f28b6dfad641
Autor:
Rossana Signorelli, Teresa Maidana Giret, Oliver Umland, Marco Hadisurya, Shweta Lavania, John Lalith Charles Richard, Ashley Middleton, Melinda Minucci Boone, Ayse Burcu Ergonul, Weiguo Andy Tao, Haleh Amirian, Anton Iliuk, Aliya Khan, Robert Diaz, Daniel Bilbao Cortes, Monica Garcia-Buitrago, Harrys Kishore Charles Jacob
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1983 (2022)
Background: Current strategies in circulating tumor cell (CTC) isolation in pancreatic cancer heavily rely on the EpCAM and cytokeratin cell status. EpCAM is generally not considered a good marker given its transitory change during Epithelial to Mese
Externí odkaz:
https://doaj.org/article/ddce2cd5e10949b5beaa86308897d635
Autor:
Stephen D. Nimer MD, Jennifer Chapman MD, Lisa Reidy PhD, Alvaro Alencar MD, YanYun Wu MD, PhD, Sion Williams PhD, Lazara Pagan MSN, Lauren Gjolaj MBA, Jessica MacIntyre MSN, Melissa Triana MBA, Barbara Vance PhD, David Andrews MD, Yao-Shan Fan MD, PhD, Yi Zhou MD, PhD, Octavio Martinez MD, Monica Garcia-Buitrago MD, Carolyn Cray PhD, Mustafa Tekin MD, Jacob L. McCauley PhD, Philip Ruiz MD, PhD, Paola Pagan MBA, Walter Lamar PhD, Maritza Alencar DNP, Daniel Bilbao PhD, Silvia Prieto MBA, Maritza Polania MBA, Maritza Suarez MD, Melissa Lujardo BSIE, Gloria Campos MSIE, Michele Morris MD, Bhavarth Shukla MD, Alberto Caban-Martinez PhD, DO, Erin Kobetz PhD, Dipen J. Parekh MD, Merce Jorda MD, PhD, MBA
Publikováno v:
Academic Pathology, Vol 7 (2020)
When South Florida became a hot spot for COVID-19 disease in March 2020, we faced an urgent need to develop test capability to detect SARS-CoV-2 infection. We assembled a transdisciplinary team of knowledgeable and dedicated physicians, scientists, t
Externí odkaz:
https://doaj.org/article/dd62565c821e4b03a7196cfab74626fb
Autor:
Ho Lam Chan, Felipe Beckedorff, Yusheng Zhang, Jenaro Garcia-Huidobro, Hua Jiang, Antonio Colaprico, Daniel Bilbao, Maria E. Figueroa, John LaCava, Ramin Shiekhattar, Lluis Morey
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The role of Polycomb Repressive Complex 1 (PRC1) is well described in development. Here, the authors investigate canonical PRC1’s regulation of transcriptional programs in breast cancer where, in addition to its repressive function, it is also recr
Externí odkaz:
https://doaj.org/article/cc957fd0d811463b9e87699141c6c633