Recruitment of Glycosyl Hydrolase Proteins in a Cone Snail Venomous Arsenal: Further Insights into Biomolecular Features of Conus Venoms

Autor: Philippe Favreau, Igor Križaj, Frédéric Ducancel, Reto Stöcklin, Florian Noguier, Sébastien Dutertre, Daniel Biass, David Piquemal, Yves Terrat, Adrijana Leonardi, Aude Violette

Publikováno v: Marine Drugs, Vol 10, Iss 2, Pp 258-280 (2012)

Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities. We report here for the first time, the presence of high molecular weight compounds that p

Externí odkaz: https://doaj.org/article/360dc13bf7ad462ba8565e873bf90c20

Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor

Autor: C. Petrel, Daniel Biass, Gregory Upert, Rolf Boelens, Henry G. Hocking, Oliver Hartley, M. Reynaud, Denis Servent, Reto Stöcklin, Ph Favreau, N. Gilles, Jan Tytgat, Steve Peigneur, Marianne Paolini-Bertrand

Publikováno v: Biochemical Pharmacology
Biochemical pharmacology
Biochemical Pharmacology, 2013, 85 (11), pp.1663-1671. ⟨10.1016/j.bcp.2013.03.019⟩
Biochemical Pharmacology, 85(11), 1663. Elsevier
Biochemical Pharmacology, Vol. 85, No 11 (2013) pp. 1663-71

Conopeptides are a diverse array of small linear and reticulated peptides that interact with high potency and selectivity with a large diversity of receptors and ion channels. They are used by cone snails for prey capture or defense. Recent advances

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916dde4711c9de807888bbc808305208

Recruitment of Glycosyl Hydrolase Proteins in a Cone Snail Venomous Arsenal: Further Insights into Biomolecular Features of Conus Venoms

Autor: Igor Križaj, Sébastien Dutertre, Daniel Biass, Philippe Favreau, Reto Stöcklin, Yves Terrat, David Piquemal, Florian Noguier, Aude Violette, Adrijana Leonardi, Frédéric Ducancel

Publikováno v: Marine Drugs
Marine Drugs; Volume 10; Issue 2; Pages: 258-280
Marine drugs
Marine drugs, MDPI, 2012, 10 (12), pp.258-280. ⟨10.3390/md10020258⟩
Marine drugs, 2012, 10 (12), pp.258-280. ⟨10.3390/md10020258⟩
Marine Drugs, Vol 10, Iss 2, Pp 258-280 (2012)

International audience; Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities. We report here for the first time, the presence of high molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26c7810e85cb9eb221729af54fd1a5a
http://europepmc.org/articles/PMC3296996

Conus consors snail venom proteomics proposes functions, pathways, and novel families involved in its venomic system

Autor: Dušan Kordiš, Reto Stöcklin, Philippe Favreau, Igor Križaj, Adrijana Leonardi, Daniel Biass

Publikováno v: Journal of proteome research. 11(10)

For some decades, cone snail venoms have been providing peptides, generally termed conopeptides, that exhibit a large diversity of pharmacological properties. However, little attention has been devoted to the high molecular mass (HMM) proteins in ven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a41b75b43bb0209a402211f67bb983
https://pubmed.ncbi.nlm.nih.gov/22928724

High-resolution picture of a venom gland transcriptome: Case study with the marine snail Conus consors

Autor: David Piquemal, Yves Terrat, Sébastien Dutertre, Maido Remm, Philippe Favreau, Reto Stöcklin, Frédéric Ducancel, Daniel Biass

Publikováno v: Toxicon
Toxicon, Elsevier, 2012, 59 (1), pp.34-46. ⟨10.1016/j.toxicon.2011.10.001⟩
Toxicon, 2012, 59 (1), pp.34-46. ⟨10.1016/j.toxicon.2011.10.001⟩

International audience; Although cone snail venoms have been intensively investigated in the past few decades, little is known about the whole conopeptide and protein content in venom ducts, especially at the transcriptomic level. If most of the prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da546fafbfc56ae2662beac6419c3e6b
https://hal.archives-ouvertes.fr/hal-02306902