Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel Bergström"'
Autor:
Damian R. Page, Susana Puig, Brigitte Dréno, Frank Gilberg, Jean-Jacques Grob, Axel Hauschild, Gary S. Rogers, Rainer Kunstfeld, Dirk Schadendorf, Daniel Bergström, Scott W. Fosko, Bruno Labeille, David Zloty
Publikováno v:
The Lancet Oncology. 18:404-412
Summary Background Vismodegib, a first-in-class Hedgehog-pathway inhibitor, is approved for use in adults with advanced basal-cell carcinoma. Patients with multiple basal-cell carcinomas, including those with basal-cell nevus (Gorlin) syndrome, need
Autor:
C William, Hanke, Shivani K, Mhatre, David, Oliveri, Marko, Zivkovic, Ivor, Caro, Daniel, Bergström, Keith, Dawson, Camelia S, Sima
Publikováno v:
Journal of drugs in dermatology : JDD. 17(2)
Information is limited on the use of vismodegib for treatment of advanced basal cell carcinoma beyond the setting of clinical trials.To investigate the treatment patterns and characteristics of patients treated with vismodegib in clinical practice.A
Autor:
Birgitta Lindh, Jonas Bergh, Hans Nordgren, Elisabet Lidbrink, Lena Malmberg, Carl Blomqvist, John Ohd, Johan Ahlgren, Daniel Bergström, Kenneth Villman
Publikováno v:
European Journal of Cancer. 43:1153-1160
To assess the efficacy and safety of epirubicin, capecitabine and cisplatin (EXC) combination therapy in locally advanced breast cancer (LABC) and investigate the predictive value of selected biomarkers.Newly diagnosed LABC patients received four 3-w
Autor:
Kristofer Rubin, Thérèse Dahlman, Ellen Lammerts, Daniel Bergström, Nils-Erik Heldin, Åsa Franzén, Kerstin Westermark
Publikováno v:
International Journal of Cancer. 98:186-192
Fibrosis in solid malignancies plays a significant role in tumor pathophysiology. Potential mechanisms for collagen type I deposition in anaplastic thyroid carcinoma (ATC) were investigated using 6 characterized ATC cell lines. Three of these cell li
Autor:
Axel Hauschild, Gary S. Rogers, Frank Gilberg, Ian A. Maher, Brigitte Dréno, Dirk Schadendorf, Bruno Labeille, Susana Puig, Daniel Bergström, Rainer Kunstfeld, David Zloty, Jean-Jacques Grob
Publikováno v:
Journal of Clinical Oncology. 34:9509-9509
9509Background: VISMO, a first-in-class Hedgehog pathway inhibitor, is approved for use in adult pts with advanced BCC. Pts with multiple BCCs, including BCC nevus syndrome (BCCNS), require VISMO t...
Autor:
Thèrése, Dahlman, Ellen, Lammerts, Daniel, Bergström, Asa, Franzén, Kerstin, Westermark, Nils-Erik, Heldin, Kristofer, Rubin
Publikováno v:
International journal of cancer. 98(2)
Fibrosis in solid malignancies plays a significant role in tumor pathophysiology. Potential mechanisms for collagen type I deposition in anaplastic thyroid carcinoma (ATC) were investigated using 6 characterized ATC cell lines. Three of these cell li
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 10(8)
The FRTL-5 rat thyroid cell line is widely used for studies of thyrocyte function and growth. The objective of the present study was to investigate the effects of hepatocyte growth factor (HGF) on FRTL-5 cells. HGF has previously been known to be a p
Autor:
Majstin Wik, Kristofer Rubin, Nils-Erik Heldin, Thérèse Dahlman, Lars Grimelius, Ellen Lammerts, Daniel Bergström, Kerstin Westermark
Publikováno v:
The Journal of pathology. 191(4)
The mechanisms involved in stromal reactions and fibrosis in solid malignant tumours are incompletely understood. In the present study, collagen type I production was investigated in tissues and cell lines derived from human undifferentiated (anaplas
Autor:
Daniel Bergström, Nils-Erik Heldin, Annika Bergenstråhle, Annika Hermansson, Bengt Westermark, Atsuhito Nakao, Peter ten Dijke
Publikováno v:
Molecular and cellular endocrinology. 153(1-2)
Transforming growth factor-beta (TGF-beta) is a multifunctional cytokine. In the present study we have investigated the expression of TGF-beta receptors (TbetaR's) and SMAD proteins in non-neoplastic and neoplastic thyroid follicle cells. We found ex
Autor:
Fredrik Olsson, Krisztián Bogár, Per I. Arvidsson, Daniel Bergström, Paulina Appelkvist, Jonas Malmborg, Rebecka Klintenberg, Fredrik Lake, Kia Strömberg, Christian Linde, Istvan Macsari, Ellen Santangelo, Ann-Cathrine Radesäter, Kim Paulsen, Ulrika Yngve, Yevgeni Besidski, M. Sundstrom
Publikováno v:
MedChemComm. 4:422
The structure–activity relationship for a series of potent γ-secretase modulators based on the 6,7-dihydro-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one scaffold is described. Furthermore, we report details regarding the modulator profile on Aβ proces