Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daniel B. Zamler"'
Autor:
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
It is essential to improve our understanding of the features that influence aggressiveness and invasion in high grade gliomas (HGG). Here, the authors characterize dynamic anatomical structures in HGG called oncostreams, which are associated with tum
Externí odkaz:
https://doaj.org/article/3b351a9de1174a41bae1168e3664c972
Autor:
Fatma Betul Aksoy Yasar, Takashi Shingu, Daniel B. Zamler, Mohammad Fayyad Zaman, Derek Lin Chien, Qiang Zhang, Jiangong Ren, Jian Hu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Glioblastoma (GBM) is a high-grade, aggressive brain tumor with dismal median survival time of 15 months. Chromosome 6q (Ch6q) is a hotspot of genomic alterations, which is commonly deleted or hyper-methylated in GBM. Two neighboring genes in this re
Externí odkaz:
https://doaj.org/article/bc98eecd8e994e478679c277d4c85a2a
Autor:
Daniel B. Zamler, Takashi Shingu, Laura M. Kahn, Kristin Huntoon, Cynthia Kassab, Martina Ott, Katarzyna Tomczak, Jintan Liu, Yating Li, Ivy Lai, Rocio Zorilla-Veloz, Cassian Yee, Kunal Rai, Betty Y.S. Kim, Stephanie S. Watowich, Amy B. Heimberger, Giulio F. Draetta, Jian Hu
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Novel therapeutic strategies targeting glioblastoma (GBM) often fail in the clinic, partly because preclinical models in which hypotheses are being tested do not recapitulate human disease. To address this challenge, we took advantage of our previous
Externí odkaz:
https://doaj.org/article/f2d1aec989ba484691463ec5f1531b0b
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2d7183c131fc5ac4baa12edf662bac
https://doi.org/10.1158/1078-0432.22466066
https://doi.org/10.1158/1078-0432.22466066
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Purpose: One likely cause of treatment failure in glioblastoma is the persistence of glioma stem-like cells (GSLCs) which are highly resistant to therapies currently employed. We found that CXCL12 has highest expression in glioma cells derived from n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ccdb9c11e31329f983061021e4ad73
https://doi.org/10.1158/1078-0432.c.6526232.v1
https://doi.org/10.1158/1078-0432.c.6526232.v1
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a2469a9c79e6d7b832140e075d0e4b
https://doi.org/10.1158/1078-0432.22466063
https://doi.org/10.1158/1078-0432.22466063
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Tumors induced from NPCs with NRAS/LgT harbor histological hallmarks of human GBM: S.2 B.Large tumors induced with NRAS/LgT are devoid of patent vascularization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677b5763d3aa6ea5f94692e7e785e432
https://doi.org/10.1158/1078-0432.22466087
https://doi.org/10.1158/1078-0432.22466087
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Genetic knockdown of CXCR4 impairs the growth of NRAS/LgT derived glioma neurospheres in vitro, decreases tumor growth in vivo and increases survival of tumor-bearing animals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825e31af2e0171ba86a910200e7eea79
https://doi.org/10.1158/1078-0432.22466075.v1
https://doi.org/10.1158/1078-0432.22466075.v1
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
CXCL12 has highest expression in GBM cells induced with NRAS/SV40 LgT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1716a1ad9acb35f2958b4e8c1a26517a
https://doi.org/10.1158/1078-0432.22466081.v1
https://doi.org/10.1158/1078-0432.22466081.v1
Autor:
Maria Graciela Castro, Pedro Ricardo Lowenstein, Maithreyi Srikanth, Robert Doherty, Daniel B. Zamler, Dustin Tran, Padma Kadiyala, Erica Carballo, Viveka Nand Yadav, Anda-Alexandra Calinescu
Comparison of gene expression between the NPC derived glioma cells M7, GL26 and GL26A1 cells (Affymetrix Gene Chip Data).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dc9b57d4d040a5e150b2e3b6f753e3
https://doi.org/10.1158/1078-0432.22466072
https://doi.org/10.1158/1078-0432.22466072