Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Daniel B. Rubinstein"'
Autor:
Michael Chalick, Oded Jacobi, Edward Pichinuk, Christian Garbar, Armand Bensussan, Alan Meeker, Ravit Ziv, Tania Zehavi, Nechama I Smorodinsky, John Hilkens, Franz-Georg Hanisch, Daniel B Rubinstein, Daniel H Wreschner
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165031 (2016)
Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in hum
Externí odkaz:
https://doaj.org/article/e148be4c47a04d5dbe84a96ede250065
Autor:
Thierry Guillaume, Edward Pichinuk, Gabi Haran, Ravit Ginat-Koton, Armand Bensussan, Daniel B. Rubinstein, Michael Chalik, Daniel H. Wreschner, Alan K. Meeker, Christian Garbar, Ravit Ziv, Itai Benhar, Nechama I. Smorodinsky
Publikováno v:
Cancer Immunology, Immunotherapy. 69:1337-1352
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain, a stable cell-s
Autor:
Daniel H. Wreschner, Pierre Peterlin, Edward Pichinuk, Patrice Chevallier, Virginie Dehame, Alice Garnier, Daniel B. Rubinstein, Marc Grégoire, Thierry Guillaume
Publikováno v:
Experimental Hematology
Experimental Hematology, Elsevier, 2019, 70, pp.97-108. ⟨10.1016/j.exphem.2018.12.002⟩
Experimental Hematology, 2019, 70, pp.97-108. ⟨10.1016/j.exphem.2018.12.002⟩
Experimental Hematology, Elsevier, 2019, 70, pp.97-108. ⟨10.1016/j.exphem.2018.12.002⟩
Experimental Hematology, 2019, 70, pp.97-108. ⟨10.1016/j.exphem.2018.12.002⟩
International audience; Cell surface molecules aberrantly expressed or overexpressed by myeloid leukemic cells represent potential disease-specific therapeutic targets for antibodies. MUC1 is a polymor-phic glycoprotein, the cleavage of which yields
Autor:
Edward, Pichinuk, Michael, Chalik, Itai, Benhar, Ravit, Ginat-Koton, Ravit, Ziv, Nechama I, Smorodinsky, Gabi, Haran, Christian, Garbar, Armand, Bensussan, Alan, Meeker, Thierry, Guillaume, Daniel B, Rubinstein, Daniel H, Wreschner
Publikováno v:
Cancer immunology, immunotherapy : CII. 69(7)
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain, a stable cell-s
Autor:
Edward Pichinuk, Daniel B. Rubinstein, Daniel H. Wreschner, Christian Garbar, Armand Bensussan, John Hilkens, Alan K. Meeker, Nechama I. Smorodinsky, Michael Chalick, Ravit Ziv, Oded Jacobi, Tania Zehavi, Franz-Georg Hanisch
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0165031 (2016)
PLoS ONE, Vol 11, Iss 10, p e0165031 (2016)
Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in hum
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 2(1)
Autor:
Ravit Ziv, Daniel H. Wreschner, Oded Jacobi, Lotem Weiss, Daniel B. Rubinstein, Edward Pichinuk, Nechama I. Smorodinsky, Carolyn Sympson, Amolkumar Karwa, Michael Chalik, Itai Benhar
Publikováno v:
Cancer Research. 72:3324-3336
The cell-surface glycoprotein MUC1 is a particularly appealing target for antibody targeting, being selectively overexpressed in many types of cancers and a high proportion of cancer stem–like cells. However the occurrence of MUC1 cleavage, which l
Autor:
Daniel H. Wreschner, Fiana Levitin, Chava Gil-Henn, Ravit Ziv, Nechama I. Smorodinsky, Mordechai Weiss, Daniel B. Rubinstein, Zofnat Prokocimer, Omer Stern
Publikováno v:
Journal of Biological Chemistry. 280:33374-33386
MUC1, a glycoprotein overexpressed by a variety of human adenocarcinomas, is a type I transmembrane protein (MUC1/TM) that soon after its synthesis undergoes proteolytic cleavage in its extracellular domain. This cleavage generates two subunits, alph
Autor:
Alexei Stortchevoi, Ellinor I.B. Peerschke, Daniel B. Rubinstein, Thierry Guillaume, Raheela Ashfaq, Michael S. Boosalis, Fabien Calvo, Berhane Ghebrehiwet
Publikováno v:
International Journal of Cancer. 110:741-750
Combinatorial Ig libraries with phage display allow in vitro generation of human Ig fragments without the need to maintain hybridomas in ongoing cell culture or to select circulating Ig from human serum. Identifying tumor-associated antigens on the s
Publikováno v:
Best Practice & Research Clinical Haematology. 12:293-306
Haematological recovery following autologous peripheral blood stem cell treatment is very rapid. Immune recovery is a more prolonged process requiring a year or more for full reconstitution. Because high-dose chemotherapy followed by autologous perip