Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Daniel B. Moran"'
1
The synthesis and biological activity of 8-fluoro-9-(4-methyl-1-piperazinyl)-6-oxo-6H-benzo[c]quinolizine-5-carboxylic acid
Autor: Carl B. Ziegler, Thomas J. Fenton, Yang-I Lin, Daniel B. Moran
Publikováno v: Journal of Heterocyclic Chemistry. 27:587-589
A one-pot synthesis of ethyl 8,9-difluoro-6-oxo-6H-benzo[c]quinolizine-5-carboxylate 11 has been developed. The condensation of ethyl 2-pyridylacetate and 2,4,5-trifluorobenzoyl chloride followed by intramolecular nucleophilic aromatic substitution g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98c0b8446789683598d36c4ea908fc85
https://doi.org/10.1002/jhet.5570270321
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4
The use of α-(aryl)-4-morpholineacetonitriles (masked acyl anion equivalents) in 1,4-additions to α,β-unsaturated esters and nitriles. A versatile synthetic route to 6-aryl-3(2H) pyridazinones
Autor: Daniel B. Moran, Jay D. Albright, Francis J. McEvoy
Publikováno v: Journal of Heterocyclic Chemistry. 15:881-892
The use of α-(substituted-phenyl)-4-morpholineacetonitriles in 1,4-additions to ethyl acrylate, ethyl crotonate, methyl α-methylacrylate, acrylonitrile, methylacrylonitrile, crotononitrile and cinnamonitrile was studied. A convenient route to 6-ary
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14d08bc1b25b5c26e135f87b8061eca6
https://doi.org/10.1002/jhet.5570150601
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5
Synthesis of novel 5-fluoro analogs of norfloxacin and ciprofloxacin
Autor: Yang I Lin, N. A. Kuck, Theresa S. Dunne, Carl B. Ziegler, Daniel B. Moran
Publikováno v: Journal of Medicinal Chemistry. 32:1313-1318
A series of polyfluoro-3-quinolonecarboxylic acids have been synthesized and their in vitro antibacterial activity evaluated. The desired 7-(substituted amino) derivatives were prepared from the 5,6,7,8-tetrafluoroquinolone acids. Conversely, amine d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c11e834a4862ff805e8961e35c8f3c
https://doi.org/10.1021/jm00126a028
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6
Synthesis of (pyridinyl)-1,2,4-triazolo[4,3-a]pyridines
Autor: J. Donald Albright, George O. Morton, Daniel B. Moran
Publikováno v: Journal of Heterocyclic Chemistry. 23:1071-1077
Methods for the synthesis of (pyridinyl)-1,2,4-triazolo[4,3-a]pyridines were developed. The principal route to the required intermediate 2-chloropyridines was based on rearrangements of mono N-oxides of 2,2′-bipyridine, 2,3′-bipyridine, 3,3′-bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cf174c7ceb8fb7dd8ed240d2c61b9c7
https://doi.org/10.1002/jhet.5570230422
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7
Synthesis of 4-aroyl-5-nitro-1H-imidazoles and 4-aroyl-5-aminoimidazoles
Autor: J. Donald Albright, Daniel B. Moran
Publikováno v: Journal of Heterocyclic Chemistry. 23:913-919
The reaction of α-(aryl)-4-morpholineacetonitriles (masked aroyl anion equivalents) with N-protected 4(5)-bromo-5(4)-nitro-1H-imidazoles gave 4-aroyl-5-nitroimidazoles which were reduced to afford 4-aroyl-5-aminoimidazoles.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa3094c57cb893b4e97da75523d4805d
https://doi.org/10.1002/jhet.5570230350
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9
ChemInform Abstract: Synthesis of (Pyridinyl)-1,2,4-triazolo(4,3-a)pyridines
Autor: George O. Morton, J. Donald Albright, Daniel B. Moran
Publikováno v: ChemInform. 18
Methods for the synthesis of (pyridinyl)-1,2,4-triazolo[4,3-a]pyridines were developed. The principal route to the required intermediate 2-chloropyridines was based on rearrangements of mono N-oxides of 2,2′-bipyridine, 2,3′-bipyridine, 3,3′-bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55d5026f5ae07063514fff2662ab1ac3
https://doi.org/10.1002/chin.198719185
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