Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Daniel B. Magilavy"'
Autor:
Elliott B. Grossbard, Theresa K. Musser, Michael E. Weinblatt, David Jones, Daniel B. Magilavy, Mark C. Genovese, Arthur Kavanaugh
Publikováno v:
The Journal of Rheumatology. 40:369-378
Objective.To assess the influence of fostamatinib on patient-reported outcomes (PRO) in patients with active rheumatoid arthritis and an inadequate response to methotrexate (MTX).Methods.Patients taking background MTX (N = 457) were enrolled in a pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc9430e72395b12be7c27de699ccbdd
https://doi.org/10.3899/jrheum.120923
https://doi.org/10.3899/jrheum.120923
Autor:
Elliott B. Grossbard, Michael E. Weinblatt, Mark C. Genovese, Daniel B. Magilavy, Julie C DiCarlo, Maryann O'Brien, Arthur Kavanaugh, Charles Peterfy, Michael L. White
Publikováno v:
Arthritis and rheumatism. 63(2)
Objective To assess the efficacy and safety of R788 (fostamatinib disodium), an inhibitor of spleen tyrosine kinase (Syk), in patients with active rheumatoid arthritis (RA) that did not respond to biologic therapies. Methods A total of 219 patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b994ce5aff44789e56e8a0a8f9bc559
https://pubmed.ncbi.nlm.nih.gov/21769845
https://pubmed.ncbi.nlm.nih.gov/21769845
Autor:
Daniel B. Magilavy, Edem E. Ekwo, Charles H. Spencer, Linda Wagner-Weiner, Liora Harel, Andrew K. Poznanski
Publikováno v:
Arthritis & Rheumatism. 36:1370-1374
Objective. To assess the effects of methotrexate (MTX) therapy on radiologic progression in juvenile rheumatoid arthritis (JRA). Methods. We evaluated serial wrist radiographs for carpal length in 23 JRA patients with bilateral wrist involvement, bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f5830bfd00f2f380da6d314535f989
https://doi.org/10.1002/art.1780361007
https://doi.org/10.1002/art.1780361007
Autor:
Elliott B. Grossbard, Michael E. Weinblatt, Daniel B. Magilavy, Theresa K. Musser, Arthur Kavanaugh, Mark C. Genovese
Publikováno v:
The New England journal of medicine. 363(14)
Background Spleen tyrosine kinase (Syk) is an important modulator of immune signaling. The objective of this phase 2 study was to evaluate the efficacy and safety of R788, an oral inhibitor of Syk, in patients with active rheumatoid arthritis despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6cbad140233968e5648aebef104cce
https://pubmed.ncbi.nlm.nih.gov/21748415
https://pubmed.ncbi.nlm.nih.gov/21748415
Publikováno v:
European Journal of Immunology. 22:2359-2365
Hepatic nonparenchymal cells (NPC) from mice of nonautoimmune strains support the proliferation of only Th1 and not Th2 helper T lymphocyte (HTL) clones. Because of the multiple systemic and liver-specific immune defects in the autoimmune MRL/lpr mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed4c85c9c191a3f837bec2f865f9691
https://doi.org/10.1002/eji.1830220927
https://doi.org/10.1002/eji.1830220927
Publikováno v:
Rheumatic Disease Clinics of North America. 17:843-857
Juvenile rheumatoid arthritis (JRA) is the most common rheumatic disease of childhood. Although the etiology remains unknown, immunoregulatory imbalances are thought to be important in the pathogenesis of JRA. Numerous immunologic abnormalities have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de1004afc959c0836c0c603fe2beee0c
https://doi.org/10.1016/s0889-857x(21)00131-9
https://doi.org/10.1016/s0889-857x(21)00131-9
Publikováno v:
Journal of pediatric gastroenterology and nutrition. 23(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a13b31c77570d255d031f4e1c63c3b
https://pubmed.ncbi.nlm.nih.gov/8956190
https://pubmed.ncbi.nlm.nih.gov/8956190
Publikováno v:
The Biochemical journal. 292
Deficiency of hepatic lipase (HL) may play a role in the lipoprotein abnormalities in chronic inflammatory states which are characterized by reticuloendothelial-system activation and cytokine release. HL triacylglycerol hydrolase activity was measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eee9b39c2dd077ba3cd40698e8fec4e
https://pubmed.ncbi.nlm.nih.gov/8503853
https://pubmed.ncbi.nlm.nih.gov/8503853
Publikováno v:
Cellular immunology. 125(2)
Immunoregulatory abnormalities in the MRL/lpr mouse strain include activation of macrophages and hepatic natural killer cells, spontaneous production of tumor necrosis factor, defective oral tolerance, and impaired production of interleukin-2. Becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ba9fcbd8d0c6122a41e5c5444ddd17
https://pubmed.ncbi.nlm.nih.gov/2137036
https://pubmed.ncbi.nlm.nih.gov/2137036
Autor:
Daniel B. Magilavy
Publikováno v:
Clinical Orthopaedics and Related Research. 259:38
The use of animals has been indispensable to the investigation of the etiology, pathophysiology, and treatment of juvenile arthritis. Because of ethical concerns about studying children, the difficulty of obtaining tissue, and the heterogeneous manif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4592891470d111d9b82b902a1c58344e
https://doi.org/10.1097/00003086-199010000-00007
https://doi.org/10.1097/00003086-199010000-00007