Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Daniel B. Forger"'
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Circadian (daily) timekeeping is essential to the survival of many organisms. An integral part of all circadian timekeeping systems is negative feedback between an activator and repressor. However, the role of this feedback varies
Externí odkaz:
https://doaj.org/article/9e15a81a72ef4cf8bde4db280f5ed769
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-9 (2021)
Abstract While 24-h total sleep time (TST) is established as a critical driver of major depression, the relationships between sleep timing and regularity and mental health remain poorly characterized because most studies have relied on either self-re
Externí odkaz:
https://doaj.org/article/fe521c3e0ca747da8672a7fac84a79b3
Autor:
Yitong Huang, Caleb Mayer, Olivia J. Walch, Clark Bowman, Srijan Sen, Cathy Goldstein, Jonathan Tyler, Daniel B. Forger
Publikováno v:
Frontiers in Digital Health, Vol 3 (2021)
Mobile measures of human circadian rhythms (CR) are needed in the age of chronotherapy. Two wearable measures of CR have recently been validated: one that uses heart rate to extract circadian rhythms that originate in the sinoatrial node of the heart
Externí odkaz:
https://doaj.org/article/11a45d2cf1784502b330eca81400c15a
Autor:
Clark Bowman, Yitong Huang, Olivia J. Walch, Yu Fang, Elena Frank, Jonathan Tyler, Caleb Mayer, Christopher Stockbridge, Cathy Goldstein, Srijan Sen, Daniel B. Forger
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 4, Pp 100058- (2021)
Summary: Millions of wearable-device users record their heart rate (HR) and activity. We introduce a statistical method to extract and track six key physiological parameters from these data, including an underlying circadian rhythm in HR (CRHR), the
Externí odkaz:
https://doaj.org/article/58e021495b4440aaa4a5088ae4739a24
Autor:
Adam R. Stinchcombe, Caiping Hu, Olivia J. Walch, Samuel D. Faught, Kwoon Y. Wong, Daniel B. Forger
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Proper circadian photoentrainment is crucial for the survival of many organisms. In mammals, intrinsically photosensitive retinal ganglion cells (ipRGCs) can use the photopigment melanopsin to sense light independently from rod and cone photoreceptor
Externí odkaz:
https://doaj.org/article/cdf7053353314c6ea12b5941fcbd38bc
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1418-1425 (2017)
Summary: The suprachiasmatic nuclei (SCN), the site of the mammalian circadian (daily) pacemaker, contains thousands of interconnected neurons, some of which receive direct retinal input. Here, we study the fast (
Externí odkaz:
https://doaj.org/article/f99057ca40414b9b84553052897ef974
Autor:
Jodi R. Paul, Daniel DeWoskin, Laura J. McMeekin, Rita M. Cowell, Daniel B. Forger, Karen L. Gamble
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
It is not clear how circadian biochemical cascades are encoded into neural electrical signals. Here, using a combination of electrophysiology and modelling approaches in mice, the authors show activation of glycogen synthase kinase 3 modulates neural
Externí odkaz:
https://doaj.org/article/55cf1eed826d46158f2e65325000bb43
Publikováno v:
Cell Reports, Vol 15, Iss 4, Pp 683-691 (2016)
Migrating eastern North American monarch butterflies use a time-compensated sun compass to adjust their flight to the southwest direction. Although the antennal genetic circadian clock and the azimuth of the sun are instrumental for proper function o
Externí odkaz:
https://doaj.org/article/5a2cffd0985c4259b151fa3a5c19adba
Autor:
Caroline H. Ko, Yujiro R. Yamada, David K. Welsh, Ethan D. Buhr, Andrew C. Liu, Eric E. Zhang, Martin R. Ralph, Steve A. Kay, Daniel B. Forger, Joseph S. Takahashi
Publikováno v:
PLoS Biology, Vol 8, Iss 10 (2010)
Externí odkaz:
https://doaj.org/article/cf30350908a34070b37c9b124827eeda
Autor:
Ningyuan Wang, Daniel B. Forger
Publikováno v:
Journal of Computational Physics. 488:112157
A wide variety of biological phenomena can be modeled by the collective activity of a population of individual units. A common strategy for simulating such a system, the population density approach, is to take the macroscopic limit and update its pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee07d416127f3bece7f43c5c3df38fbe
https://doi.org/10.1016/j.jcp.2023.112157
https://doi.org/10.1016/j.jcp.2023.112157