Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Daniel B. Drachman"'
Publikováno v:
Toxins, Vol 2, Iss 12, Pp 2872-2889 (2010)
Although advances in understanding of the pathogenesis of amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) have suggested attractive treatment strategies, delivery of agents to motor neurons embedded within the spinal cord is pro
Externí odkaz:
https://doaj.org/article/f4e2fae6430c444aa4eb871f42746e43
Autor:
Joel Oger, Joshua D Green, Bryan J Traynor, Richard J Barohn, Michael Benatar, Emanuela Bartoccion, Derrick Blackmore, Manisha Chopra, Andrea Corse, Mazen M Dimachkie, Amelia Evoli, Julaine Florence, Miriam Freimer, James F Howard, Theresa Jiwa, Henry J Kaminski, John T Kissel, Wilma J Koopman, Bernadette Lipscomb, Michelanglo Maestri, Mariapaola Marino, Janice M Massey, April McVey, Michelle M Mezei, Michael W Nicolle, Robert M Pascuzzi, Mamatha Pasnoor, Alan Pestronk, Carlo Provenzano, Roberta Ricciardi, David P Richman, Julie Rowin, Donald B Sanders, Zaeem Siddiqi, Aimee Soloway, Gil I Wolfe, Charlie Wulf, Daniel B Drachman
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Objectives To approximate the rate of familial myasthenia gravis and the coexistence of other autoimmune disorders in the patients and their families.Design Retrospective cohort study.Setting Clinics across North America.Participants The study includ
Externí odkaz:
https://doaj.org/article/0145aad817a242af8725bc4e583792df
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e4297c7bb0b31926d2ca6f5b460474d
https://doi.org/10.1073/pnas.2209096119
https://doi.org/10.1073/pnas.2209096119
Autor:
Zaeem A. Siddiqi, Robert M. Pascuzzi, Mazen M. Dimachkie, David P. Richman, Richard J. Barohn, Srikanth Muppidi, Michael Benatar, Julaine Florence, M Marino, Michelanglo Maestri, Vinay Chaudhry, Theresa Jiwa, Joshua D. Green, Roberta Ricciardi, Wilma J. Koopman, Joel Oger, Bernadette Lipscomb, Daniel B. Drachman, Manisha Chopra, Amelia Evoli, Derrick Blackmore, Julie Rowin, Gil I. Wolfe, Donald B. Sanders, Michelle M. Mezei, Carlo Provenzano, Henry J. Kaminski, Andrea M. Corse, Aimee Soloway, John T. Kissel, Alan Pestronk, Janice M. Massey, Emanuela Bartoccion, Miriam Freimer, Michael W. Nicolle, Charlie Wulf, April McVey, James F. Howard, Mamatha Pasnoor, Bryan J. Traynor
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
BMJ open, vol 10, iss 9
BMJ Open
BMJ open, vol 10, iss 9
BMJ Open
ObjectivesTo approximate the rate of familial myasthenia gravis and the coexistence of other autoimmune disorders in the patients and their families.DesignRetrospective cohort study.SettingClinics across North America.ParticipantsThe study included 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b651f10dae6c6aab1c97b40cf465d5
https://bmjopen.bmj.com/content/10/9/e037909.full
https://bmjopen.bmj.com/content/10/9/e037909.full
Autor:
Lan Zhou, Robert N. Adams, Daniel B. Drachman, Richard L. Skolasky, Vinay Chaudhry, Angela Vincent, John McConville
We assayed cryopreserved sera from 38 acetylcholine receptor (AChR) antibody-negative patients with myasthenia gravis (MG) who were followed clinically for muscle-specific tyrosine kinase (MuSK) antibodies and analyzed and compared their clinical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0c6bf9327cc4e4c755074dff140d8d
https://ora.ox.ac.uk/objects/uuid:428e9a6d-0249-411c-90aa-2c4c46c23529
https://ora.ox.ac.uk/objects/uuid:428e9a6d-0249-411c-90aa-2c4c46c23529
Autor:
Daniel B. Drachman
Publikováno v:
JAMA neurology. 73(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfca8c78131eb5ce0c28f1988f88b71
https://pubmed.ncbi.nlm.nih.gov/27043206
https://pubmed.ncbi.nlm.nih.gov/27043206
Publikováno v:
Journal of Neuroimmunology. 251:25-32
Current immunotherapy of myasthenia gravis (MG) is often effective, but entails risks of infection and neoplasia. The "Guided Missile" strategy described here is designed to target and eliminate the individual's unique AChR-specific T cell repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efad056c2304c8aa531166969d81e6f
https://doi.org/10.1016/j.jneuroim.2012.06.007
https://doi.org/10.1016/j.jneuroim.2012.06.007
Autor:
Grant J. Anhalt, Richard J. Jones, Robert A. Brodsky, Fredrick M. Wigley, Hua Ling Tsai, David M. Loeb, Amy E. DeZern, Jeanne Kowalski, Edward R. Hammond, Daniel B. Drachman, Michelle Petri, Doug Kerr
Publikováno v:
Medicine. 90:89-98
High-dose cyclophosphamide has long been used as an anticancer agent, a conditioning regimen for hematopoietic stem cell transplantation, and a potent immunosuppressive agent in autoimmune diseases including aplastic anemia. High-dose cyclophosphamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4042735d0e057d3c32326cc3f10fef
https://doi.org/10.1097/md.0b013e318210e685
https://doi.org/10.1097/md.0b013e318210e685
Publikováno v:
Toxins, Vol 2, Iss 12, Pp 2872-2889 (2010)
Toxins
Volume 2
Issue 12
Pages 2872-2889
Toxins
Volume 2
Issue 12
Pages 2872-2889
Although advances in understanding of the pathogenesis of amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) have suggested attractive treatment strategies, delivery of agents to motor neurons embedded within the spinal cord is pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e1ffefd492883bd58f26d25af9bcad
http://www.mdpi.com/2072-6651/2/12/2872/
http://www.mdpi.com/2072-6651/2/12/2872/
Publikováno v:
Annals of the New York Academy of Sciences. 1132:305-314
A small but important proportion of patients with myasthenia gravis (MG) are refractory to conventional immunotherapy. We have treated 12 such patients by "rebooting" the immune system with high-dose cyclophosphamide (Hi Cy, 200 mg/kg), which largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f3b6df736c6d46e36bd6d358342b95
https://doi.org/10.1196/annals.1405.033
https://doi.org/10.1196/annals.1405.033