Výsledky vyhledávání - "Daniel B. Casey"

Recruitment of Murine Neutrophils in Vivothrough Endogenous Sialidase Activity

Autor: Frederick J. Cassels, Salahaldin Rifat, Beth Ellen Drysdale, Nicholas M. Stamatos, Alan S. Cross, Apurba K. Bhattacharjee, Ann M. Farese, Philippe A. Grange, Daniel B. Casey, Thomas K. Held, Lai-Xi Wang, Serhan Sakarya, Simeon E. Goldblum, Michael Kleinberg, Jan Powell

Publikováno v: Journal of Biological Chemistry. 278:4112-4120

Upon activation with various noncytokine stimuli, polymorphonuclear leukocytes (PMNs) mobilize intracellular sialidase to the plasma membrane, where the sialidase releases sialic acid from the cell surface. This desialylation enhances PMN adherence,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf57884f76bc9e39547ae49de2581dd
https://doi.org/10.1074/jbc.m207591200

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Leridistim, a chimeric dual G-CSF and IL-3 receptor agonist, enhances multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression: effect of schedule, dose, and route of administration

Autor: R. M. Vigneulle, John P. McKearn, Walter G. Smith, Thomas J. MacVittie, Daniel B. Casey, Ann M. Farese

Publikováno v: Stem cells (Dayton, Ohio). 19(6)

Leridistim is from the myelopoietin family of proteins, which are dual receptor agonists of the human interleukin-3 and G-CSF receptor complexes. This study investigated the effect of dosage, administration route, and schedule of leridistim to stimul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e015b3afc35759ae25eb699dce0ebbe8
https://pubmed.ncbi.nlm.nih.gov/11713344

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A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques

Autor: John P. Mckearn, Daniel B. Casey, Rory F. Finn, Ann M. Farese, Thomas J. MacVittie, Walter G. Smith, Ned R. Siegel, R. M. Vigneulle, Jon A. Klover

Publikováno v: Stem cells (Dayton, Ohio). 19(6)

Leridistim, a member of the myelopoietin family of dual receptor agonists that binds interleukin-3 and G-CSF receptors, has been shown to enhance hematopoietic activity in rhesus monkeys above that observed with either cytokine alone or in combinatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec81796a7a9e7b9f8531b4693cc13e7
https://pubmed.ncbi.nlm.nih.gov/11713343

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