Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daniel B Nichols"'
Autor:
Li Sun, Yaling Xing, Xiaojuan Chen, Yang Zheng, Yudong Yang, Daniel B Nichols, Mark A Clementz, Bridget S Banach, Kui Li, Susan C Baker, Zhongbin Chen
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30802 (2012)
Viruses have evolved elaborate mechanisms to evade or inactivate the complex system of sensors and signaling molecules that make up the host innate immune response. Here we show that human coronavirus (HCoV) NL63 and severe acute respiratory syndrome
Externí odkaz:
https://doaj.org/article/6ec96f38e90e415097ec935050eb3d82
Autor:
Deborah J. Lenschow, Susan C. Baker, Sudhakar Agnihothram, Scott D. Larsen, Daniel B. Nichols, Xufang Deng, Ralph S. Baric, Andrew D. Mesecar, Anna M. Mielech, Sarah E. StJohn, Michael W. Wilson
Publikováno v:
Journal of Virology
To combat emerging coronaviruses, developing safe and efficient platforms to evaluate viral protease activities and the efficacy of protease inhibitors is a high priority. Here, we exploit a biosafety level 2 (BSL-2) chimeric Sindbis virus system to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d3c47bce21b58e09312492d4446bc7
https://doi.org/10.1128/jvi.01749-14
https://doi.org/10.1128/jvi.01749-14
Autor:
Susan C. Baker, Li Sun, Bridget S. Banach, Yudong Yang, Xiaojuan Chen, Kui Li, Zhongbin Chen, Yaling Xing, Daniel B. Nichols, Mark A. Clementz, Yang Zheng
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30802 (2012)
PLoS ONE
PLoS ONE
Viruses have evolved elaborate mechanisms to evade or inactivate the complex system of sensors and signaling molecules that make up the host innate immune response. Here we show that human coronavirus (HCoV) NL63 and severe acute respiratory syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92823670e5eb20764895b0a5e56c828d
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22312431/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22312431/pdf/?tool=EBI
Autor:
Susan C. Baker, Kiira Ratia, Michael E. Johnson, Jun Takayama, Katrina Sleeman, Andrew D. Mesecar, Debbie C. Mulhearn, Yoann Aubin, Arun K. Ghosh, Rima Chaudhuri, Bellur S. Prabhakar, Daniel B. Nichols, Melissa M. Coughlin, Yahira Baez
Publikováno v:
Journal of Medicinal Chemistry
We describe here the design, synthesis, molecular modeling, and biological evaluation of a series of small molecule, nonpeptide inhibitors of SARS-CoV PLpro. Our initial lead compound was identified via high-throughput screening of a diverse chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5d441c15a74b3ca299b67dc7e1f480
https://europepmc.org/articles/PMC3148848/
https://europepmc.org/articles/PMC3148848/
Autor:
Arun K. Ghosh, Jun Takayama, Yoann Aubin, Kiira Ratia, Rima Chaudhuri, Yahira Baez, Katrina Sleeman, Melissa Coughlin, Daniel B. Nichols, Debbie C. Mulhearn, Bellur S. Prabhakar, Susan C. Baker, Michael E. Johnson, Andrew D. Mesecar
Publikováno v:
Journal of Medicinal Chemistry; Aug2009, Vol. 52 Issue 16, p5228-5240, 13p