Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel B, Lyle"'
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:305-314
This study examined the effect of hyaluronan (HA) molecular weight on immune response. HA with molecular weights ranging from the unitary disaccharide unit (400 Da) up to 1.7 × 10(6) Da and with very low endotoxin contamination level (less than 0.03
Publikováno v:
Journal of Biomedical Materials Research Part A. :205-213
Complement plays an important role in the immune attack against invading microorganisms. However, blood-contacting medical device biomaterials lacking specific complement inhibitors, with free hydroxyl and/or amino groups, or with absorbed antibodies
Publikováno v:
Journal of Biomedical Materials Research Part A. :1221-1238
Chronic inflammation may compromise function of implanted encapsulated islets. Increased purity of alginate used for encapsulation prolongs encapsulated graft function, correlating with decreased presence of impurities like bacterial endotoxin. Limit
Publikováno v:
Bioelectromagnetics. 19:123-127
The objective of this study was to develop a model for testing various hypotheses concerning possible mechanisms whereby electromagnetic fields might induce suppression of nighttime melatonin production in rodents. A published method for digesting fr
Publikováno v:
Bioelectromagnetics. 18:439-445
To explore possible biochemical mechanisms whereby electromagnetic fields of around 0.1 mT might affect immune cells or developing cancer cells, we studied intracellular calcium signaling in the model system Jurkat E6-1 human T-leukemia cells during
Publikováno v:
Journal of biomedical materials research. Part A. 102(2)
This study examined the effect of hyaluronan (HA) molecular weight on immune response. HA with molecular weights ranging from the unitary disaccharide unit (400 Da) up to 1.7 × 10(6) Da and with very low endotoxin contamination level (less than 0.03
Publikováno v:
Bioelectrochemistry and Bioenergetics. 34:39-43
Extremely low frequency electromagnetic fields (EMFs) are implicated in the genesis of childhood leukemias and lymphomas after residential exposure, and of tumors in adults after occupational exposure. Experiments in vitro have demonstrated biochemic
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 91(2)
Since current purification methods cannot completely remove all traces of endotoxin in biomaterials intended for use in implantable or blood-contacting devices, acceptable levels of endotoxin contamination that will not cause a significant inflammato
Autor:
Charles N. Durfor, Daniel B. Lyle, John J. Langone, Jonathan C. Shallcross, Victoria M. Hitchins, Joyce C. Breger
Publikováno v:
Journal of biomedical materials research. Part A. 90(1)
Inflammatory reactions to biomaterials may include macrophage-mediated generation of nitric oxide (NO), which may harm patient tissue or potentially interfere with proper function of an implanted device. RAW 264.7 cells were grown in culture and trea
Publikováno v:
Bioelectromagnetics. 9:303-313
A significant 25% inhibition (P less than .005) of allogeneic cytotoxicity of the target cell MPC-11 by the murine cytotoxic T-lymphocyte line CTLL-1 was observed when the 4-h cytotoxicity assay was conducted immediately following a 48-h pre-exposure