Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Daniel Auguin"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 7955-7975 (2024)
Aquaporins (AQPs) are transmembrane channels initially discovered for their role in water flux facilitation through biological membranes. Over the years, a much more complex and subtle picture of these channels appeared, highlighting many other solut
Externí odkaz:
https://doaj.org/article/600404a8a545432d8fe134685f548a91
Autor:
Daniel Auguin, Julien Robert-Paganin, Stéphane Réty, Carlos Kikuti, Amandine David, Gabriele Theumer, Arndt W. Schmidt, Hans-Joachim Knölker, Anne Houdusse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Inherited cardiomyopathies are common cardiac diseases worldwide, leading in the late stage to heart failure and death. The most promising treatments against these diseases are small molecules directly modulating the force produced by β-car
Externí odkaz:
https://doaj.org/article/363d3a02b7d54aa8bbcb3c56b4a01f3f
Autor:
Dihia Moussaoui, James P. Robblee, Julien Robert-Paganin, Daniel Auguin, Fabio Fisher, Patricia M. Fagnant, Jill E. Macfarlane, Julia Schaletzky, Eddie Wehri, Christoph Mueller-Dieckmann, Jake Baum, Kathleen M. Trybus, Anne Houdusse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Malaria results in more than 500,000 deaths per year and the causative Plasmodium parasites continue to develop resistance to all known agents, including different antimalarial combinations. The class XIV myosin motor PfMyoA is part of a cor
Externí odkaz:
https://doaj.org/article/649b74fa0af0445585a6975102ee7c70
Autor:
Alessandro Grinzato, Daniel Auguin, Carlos Kikuti, Neha Nandwani, Dihia Moussaoui, Divya Pathak, Eaazhisai Kandiah, Kathleen M. Ruppel, James A. Spudich, Anne Houdusse, Julien Robert-Paganin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract To save energy and precisely regulate cardiac contractility, cardiac muscle myosin heads are sequestered in an ‘off’ state that can be converted to an ‘on’ state when exertion is increased. The ‘off’ state is equated with a folde
Externí odkaz:
https://doaj.org/article/0c05293899494749a2e39fe8e07c3200
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Ménière’s disease (MD) is characterized by an abnormal dilatation of the endolymphatic compartment called endolymphatic hydrops and is associated with fluctuating hearing losses and vertigo. Corticosteroid treatment is typically administered for
Externí odkaz:
https://doaj.org/article/c637bc17a4c644cea78047b98ec31653
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2267 (2024)
Aquaporins (AQPs) constitute a wide family of water channels implicated in all kind of physiological processes. Zinc is the second most abundant trace element in the human body and a few studies have highlighted regulation of AQP0 and AQP4 by zinc. I
Externí odkaz:
https://doaj.org/article/bbe34e9bda554e1fa2c29637cc39ade0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13798 (2023)
Aquaporins (AQPs) constitute a wide and ancient protein family of transmembrane channels dedicated to the regulation of water exchange across biological membranes. In plants, higher numbers of AQP homologues have been conserved compared to other king
Externí odkaz:
https://doaj.org/article/dda7b7aabf884f779a9b68ca8e3f5c57
Autor:
Julien Robert-Paganin, Xiao-Ping Xu, Mark F. Swift, Daniel Auguin, James P. Robblee, Hailong Lu, Patricia M. Fagnant, Elena B. Krementsova, Kathleen M. Trybus, Anne Houdusse, Niels Volkmann, Dorit Hanein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Plasmodium falciparum moves by an atypical process called gliding motility which comprises of atypical myosin A (PfMyoA) and filaments of the dynamic and divergent PfActin-1 (PfAct1). Here authors present the cryo-EM structure of PfMyoA bound to fila
Externí odkaz:
https://doaj.org/article/1e9f084757d3479aa82cffe48fcd9158
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1499 (2023)
Aquaporins (AQPs) are water channels widely distributed in living organisms and involved in many pathophysiologies as well as in cell volume regulations (CVR). In the present study, based on the structural homology existing between mineralocorticoid
Externí odkaz:
https://doaj.org/article/b05caf7f8bfb4efaa560ce4338fdf4d7
Autor:
Julien Robert-Paganin, James P. Robblee, Daniel Auguin, Thomas C. A. Blake, Carol S. Bookwalter, Elena B. Krementsova, Dihia Moussaoui, Michael J. Previs, Guillaume Jousset, Jake Baum, Kathleen M. Trybus, Anne Houdusse
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Here, Robert-Paganin et al. show that myosin A from Plasmodium falciparum is critical for red blood cell invasion and that non-canonical interactions and regulated phosphorylation are important for force generation during parasite invasion.
Externí odkaz:
https://doaj.org/article/09a7260cc76747dbb13cb2f561bcbfc8