Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniel Angus Ryan"'
Autor:
Martha Hale, Dariush Ajami, Melissa Degardin, Daniel Angus Ryan, Mitra Rebek, Michael D. Cameron, Julius Rebek, Kamal U. Saikh, Shahabuddin Alam, Teri L. Kissner
Publikováno v:
Chemical biologydrug design. 90(6)
Small molecules were developed to attenuate proinflammatory cytokines resulting from activation of MyD88-mediated toll-like receptor (TLR) signaling by Francisella tularensis. Fifty-three tripeptide derivatives were synthesized to mimic a key BB-loop
Autor:
Julius Rebek, Daniel Angus Ryan
Publikováno v:
Journal of the American Chemical Society. 133:19653-19655
A deep cavitand was covalently modified with carbohydrates to provide solubility in biologically relevant environments and to investigate its receptor function. Specifically, a tetrakis(β-D-glucosyl) cavitand (1) that was soluble in neutral water or
Autor:
Daniel Angus Ryan, Julius Rebek
Publikováno v:
The Analyst. 138(4)
A water-soluble deep cavitand recognized alkylammonium salts, including the drug amantadine hydrochloride, in spiked samples of human urine. The signals of the guests are detected by (1)H NMR upfield of 0 ppm and so occur in a spectroscopic window th