3D-Printed Plasmonic Nanocomposites: VAT Photopolymerization for Photothermal-Controlled Drug Release

Autor: Ignacia Paz Torres Fredes, Elizabeth Nicole Cortés-Adasme, Bruno Andrés Barrientos, Juan Pablo Real, Cesar Gerardo Gomez, Santiago Daniel Palma, Marcelo Javier Kogan, Daniel Andrés Real

Publikováno v: Pharmaceuticals, Vol 17, Iss 11, p 1453 (2024)

Background: Gold nanoparticles can generate heat upon exposure to radiation due to their plasmonic properties, which depend on particle size and shape. This enables precise control over the release of active substances from polymeric pharmaceutical f

Externí odkaz: https://doaj.org/article/fce52efa86ee4108955257d226dea493

A quality by design approach for optimization of Lecithin/Span® 80 based nanoemulsions loaded with hydrophobic drugs

Autor: Stefan Hoffmann, Claudio J. Salomon, Darío Leonardi, Daniel Andres Real, Francisco M. Goycoolea

Publikováno v: Journal of Molecular Liquids. 321:114743

Lately, nanoemulsions loaded with hydrophobic drugs have been successfully developed to improve the treatment of several global diseases. On this subject, a detailed study of the crucial role of the excipients and the experimental conditions used for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4097fb561076312ba4e156e84462142d
https://doi.org/10.1016/j.molliq.2020.114743

Effect of electrochemically activated water addition to the drinking water of feedlot cattle of Buenos Aires province

Autor: O. E. Osella, Julian Horacio de la Torre, Karina Pellicer, María Pía Silvestrini, Daniel Andres Real, Julio Alberto Copes, Victoria Brusa, C.A. Bainotti

Publikováno v: Analecta Veterinaria, Vol 38, Iss 1 (2018)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

El objetivo general del trabajo fue evaluar el efecto del consumo de agua electroactivada (AE) en bovinos de engorde a corral (feedlot); los objetivos particulares fueron: 1. determinar la presencia de E. coli O157 y de Salmonella spp. en materia fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f39073ce1b9af173df963561e5bca0
http://sedici.unlp.edu.ar/handle/10915/67744

Development and in vitro/in vivo evaluation of a novel benznidazole liquid dosage form using a quality-by-design approach

Autor: Darío Leonardi, Claudio J. Salomon, Victoria Lucia Alonso, Ariel Mariano Silber, Higo Fernando Santos Souza, Esteban Serra, Sandra Carla Rocha, Daniel Andres Real

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Objectives: To develop an alcohol-free solution suitable for children of benznidazole, the drug of choice for treatment of Chagas disease. Methods: In a quality-by-design approach, a systematic optimisation procedure was carried out to estimate the v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5836a78ab3502d4931e9fe30eabb5a5
Wiley Online Library

3D-Printed Gastroretentive Tablets Loaded with Niclosamide Nanocrystals by the Melting Solidification Printing Process (MESO-PP)

Autor: Juan Pablo Real, Daniel Andrés Real, Lucía Lopez-Vidal, Bruno Andrés Barrientos, Karen Bolaños, Mariano Guillermo Tinti, Nicolás Javier Litterio, Marcelo Javier Kogan, Santiago Daniel Palma

Publikováno v: Pharmaceutics, Vol 15, Iss 5, p 1387 (2023)

Niclosamide (NICLO) is a recognized antiparasitic drug being repositioned for Helicobacter pylori. The present work aimed to formulate NICLO nanocrystals (NICLO-NCRs) to produce a higher dissolution rate of the active ingredient and to incorporate th

Externí odkaz: https://doaj.org/article/5f1408cf27ce4b19980d6818d5604ee2