Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Daniel Abegg"'
Autor:
Sarrazin, Gr.
Publikováno v:
Zeitschrift für deutsches Altertum und deutsche Literatur, 1896 Jan 01. 40, 176-180.
Externí odkaz:
https://www.jstor.org/stable/20651322
Autor:
Yuquan Tong, Yeongju Lee, Xiaohui Liu, Jessica L. Childs-Disney, Blessy M. Suresh, Raphael I. Benhamou, Chunying Yang, Weimin Li, Matthew G. Costales, Hafeez S. Haniff, Sonja Sievers, Daniel Abegg, Tristan Wegner, Tiffany O. Paulisch, Elizabeth Lekah, Maison Grefe, Gogce Crynen, Montina Van Meter, Tenghui Wang, Quentin M. R. Gibaut, John L. Cleveland, Alexander Adibekian, Frank Glorius, Herbert Waldmann, Matthew D. Disney
Publikováno v:
Nature. 618:169-179
Target occupancy is often insufficient to elicit biological activity, particularly for RNA, compounded by the longstanding challenges surrounding the molecular recognition of RNA structures by small molecules. Here we studied molecular recognition pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ddd01fdc061bbc5774956f8b2b5aaea
https://doi.org/10.1038/s41586-023-06091-8
https://doi.org/10.1038/s41586-023-06091-8
Autor:
Flavien Berthou, Cyril Sobolewski, Daniel Abegg, Margot Fournier, Christine Maeder, Dobrochna Dolicka, Marta Correia de Sousa, Alexander Adibekian, Michelangelo Foti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3959 (2022)
Liver-derived circulating factors deeply affect the metabolism of distal organs. Herein, we took advantage of the hepatocyte-specific PTEN knockout mice (LPTENKO), a model of hepatic steatosis associated with increased muscle insulin sensitivity and
Externí odkaz:
https://doaj.org/article/8ee15058d76c484e9069db329c8790f1
Autor:
Samantha M. Meyer, Toru Tanaka, Patrick R. A. Zanon, Jared T. Baisden, Daniel Abegg, Xueyi Yang, Yoshihiro Akahori, Zainab Alshakarchi, Michael D. Cameron, Alexander Adibekian, Matthew D. Disney
Publikováno v:
Journal of the American Chemical Society. 144:21096-21102
Ribonuclease targeting chimeras (RiboTACs) induce degradation of an RNA target by facilitating an interaction between an RNA and a ribonuclease (RNase). We describe the screening of a DNA-encoded library (DEL) to identify binders of monomeric RNase L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fd2d6a6853884aaa97d960d447d4ac
https://doi.org/10.1021/jacs.2c07217
https://doi.org/10.1021/jacs.2c07217
Publikováno v:
ACS Central Science, Vol 3, Iss 5, Pp 449-453 (2017)
Externí odkaz:
https://doaj.org/article/3f5748a4e726404d96ab48711eb04c1c
Autor:
Yuquan Tong, Quentin M. R. Gibaut, Warren Rouse, Jessica L. Childs-Disney, Blessy M. Suresh, Daniel Abegg, Shruti Choudhary, Yoshihiro Akahori, Alexander Adibekian, Walter N. Moss, Matthew D. Disney
Publikováno v:
J Am Chem Soc
The interactions between cellular RNAs in MDA-MB-231 triple negative breast cancer cells and a panel of small molecules appended with a diazirine cross-linking moiety and an alkyne tag were probed transcriptome-wide in live cells. The alkyne tag allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6fb0cc19b69f65a725b2ce3892e36e
https://doi.org/10.1021/jacs.2c01929
https://doi.org/10.1021/jacs.2c01929
Autor:
Roman Lagoutte, Christelle Serba, Daniel Abegg, Dominic G. Hoch, Alexander Adibekian, Nicolas Winssinger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.
Externí odkaz:
https://doaj.org/article/1ed6d7b632384db6874986b87650499b
Autor:
Fei Ye, Hafeez S. Haniff, Blessy M. Suresh, Dong Yang, Peiyuan Zhang, Gogce Crynen, Christiana N. Teijaro, Wei Yan, Daniel Abegg, Alexander Adibekian, Ben Shen, Matthew D. Disney
Publikováno v:
ACS Chem Biol
The discovery of biofunctional natural products (NPs) has relied on the phenotypic screening of extracts and subsequent laborious work to dereplicate active NPs and define cellular targets. Herein, NPs present as crude extracts, partially purified fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a17d821a6f612b767b73a5ab8a2d6eb
https://doi.org/10.1021/acschembio.1c00952
https://doi.org/10.1021/acschembio.1c00952
Autor:
Daniel Abegg, Dany Pechalrieu, Anton Shuster, Hyeryun Choe, Cody B. Jackson, Alexander Adibekian
Publikováno v:
ACS Chemical Biology
Arbidol (ARB) is a broad-spectrum antiviral drug approved in Russia and China for the treatment of influenza. ARB was tested in patients as a drug candidate for the treatment at the early onset of COVID-19 caused by the novel severe acute respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9672b146a5263ad809709722fe2bab
https://doi.org/10.1021/acschembio.1c00756
https://doi.org/10.1021/acschembio.1c00756
The cepafungins are a class of highly potent and selective eukaryotic proteasome inhibitor natural products with potential to treat refractory multiple myeloma and other cancers. The structure-activity relationship of the cepafungins is not fully und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480ce56331720722e2450a66ae91177e
https://doi.org/10.26434/chemrxiv-2022-n9lzd
https://doi.org/10.26434/chemrxiv-2022-n9lzd
