Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel A. Valles"'
Publikováno v:
SynOpen, Vol 05, Iss 03, Pp 173-228 (2021)
This Graphical Review provides a concise overview of the manifold and mechanistically diverse methods that enable the functionalization of sp3 C–H bonds in amines and their derivatives.
Externí odkaz:
https://doaj.org/article/b260cc62528a4c47af2c38935cb608d1
Publikováno v:
Organic letters. 24(35)
Secondary alicyclic amines are converted to α-aminonitriles via addition of TMSCN to their corresponding imines, intermediates that are produced in situ via the oxidation of amine-derived lithium amides with simple ketone oxidants. Amines with an ex
Autor:
Nathan C. Gianneschi, Yerzhan S. Zholdassov, David R. Mootoo, Joanna Korpanty, Samiha Uddin, Adam B. Braunschweig, Yasir Naeem, Daniel J. Valles
Publikováno v:
Angewandte Chemie International Edition. 60:20350-20357
We report a novel glycan array architecture that binds the mannose-specific glycan binding protein, concanavalin A (ConA), with sub-femtomolar avidity. A new radical photopolymerization developed specifically for this application combines the grafted
Autor:
Daniel J. Valles, Yerzhan S. Zholdassov, Joanna Korpanty, Samiha Uddin, Yasir Naeem, David R. Mootoo, Nathan C. Gianneschi, Adam B. Braunschweig
Publikováno v:
Angewandte Chemie. 133:20513-20520
Publikováno v:
SynOpen, Vol 05, Iss 03, Pp 173-228 (2021)
SynOpen (2017)
SynOpen (2017)
This Graphical Review provides a concise overview of the manifold and mechanistically diverse methods that enable the functionalization of sp3 C–H bonds in amines and their derivatives.
Graphical Abstract
Graphical Abstract
Publikováno v:
Polymer Chemistry. 12:5724-5746
Hypersurface photolithography (HP) is a printing method for fabricating structures and patterns composed of soft materials bound to solid surfaces and with ∼1 micrometer resolution in the x, y, and z dimensions. This platform leverages benign, low
Autor:
Daniel A. Valles, Daniel Seidel, Anirudra Paul, Ion Ghiviriga, Khalil A. Abboud, Subhradeep Dutta
Publikováno v:
Org Lett
A simple one-pot procedure enables the sequential, regioselective, and diastereoselective introduction of the same or two different substituents to the α- and α'-positions of unprotected azacycles. Aryl, alkyl, and alkenyl substituents are introduc
Autor:
Carlos Carbonell, Courtney L. Chambers, Angelica Y. Rozenfeld, Daniel J. Valles, Adam B. Braunschweig, Rawan W. Aldasooky, Alexa M. Wong
Publikováno v:
ACS Macro Letters. 8:1474-1478
Here, we show that the surface-initiated thiol-(meth)acrylate polymerization can be used to create brush polymer patterns with precise control over the feature height at each microscale pixel. The reaction was studied using a printer where a digital
Autor:
W. Bruce Turnbull, Joseph P. Byrne, Adam B. Braunschweig, Stephan Schmidt, Jeff Gildersleeve, Daniel J. Valles, Jin Yu, Ryan C. Chiechi, Kamil Godula, Clare S. Mahon, Yuri Diaz Fernandez, Yoshiko Miura, Dejian Zhou, Alshakim Nelson, Laura Hartmann
Publikováno v:
Faraday Discussions, 219, 128-137. ROYAL SOC CHEMISTRY
Autor:
Adam B. Braunschweig, Alexa M. Wong, Carlos Carbonell, Daniel J. Valles, Yasir Naeem, David R. Mootoo
Publikováno v:
ACS biomaterials scienceengineering. 5(6)
Spatially encoded glycan microarrays promise to rapidly accelerate our understanding of glycan binding in myriad biological processes, which could lead to new therapeutics and previously unknown drug targets. Here, we bring together a digital micromi