Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel A. Polisel"'
Autor:
Alexandre A. de Castro, Letícia C. Assis, Flávia V. Soares, Kamil Kuca, Daniel A. Polisel, Elaine F. F. da Cunha, Teodorico C. Ramalho
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 436 (2020)
Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall u
Externí odkaz:
https://doaj.org/article/2dbcb7dbc70f41d5af3574e6d784cf2d
Autor:
Teodorico C. Ramalho, Kamil Kuca, Daniel A. Polisel, Daniel H. S. Leal, Elaine F. F. da Cunha, Ander Francisco Pereira, Alexandre A. de Castro, Eugenie Nepovimova, Melissa S. Caetano, Flávia V. Soares
Publikováno v:
Expert Review of Neurotherapeutics. 19:375-395
Alzheimer's disease (AD) is the most common cause of dementia. Clinical progress in this pathogenesis field has drawn the attention of researchers, stimulating the investigation of novel treatment methods. Current therapies that deal with cholinester
Autor:
Thiago Juvenal Ribeiro, Maria Tailani Borges, Rennan Alves Cardoso, Daniel Ângelo Polisel, Raquel Rezende Coelho, Daniel Furtado Leite, Sílvia Costa Costa
Publikováno v:
Desvendando a Engenharia: sua abrangência e multidisciplinaridade ISBN: 9786589826132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aab564017e15977e518c3257ab42046
https://doi.org/10.37885/210404191
https://doi.org/10.37885/210404191
Autor:
Teodorico C. Ramalho, Bruna T. L. Pereira, Elaine F. F. da Cunha, Alexandre A. de Castro, Eugenie Nepovimova, Daniel A. Polisel, Kamil Kuca
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6510, p 6510 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences
Volume 21
Issue 18
Organophosphorus (OP) compounds are used as both chemical weapons and pesticides. However, these agents are very dangerous and toxic to humans, animals, and the environment. Thus, investigations with reactivators have been deeply developed in order t
Autor:
Daniel A. Polisel, Flávia V. Soares, Teodorico C. Ramalho, Elaine F. F. da Cunha, Letícia C. Assis, Alexandre A. de Castro, Kamil Kuca
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 436 (2020)
Biomolecules
Biomolecules
Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall u
Autor:
Teodorico C. Ramalho, Elaine F.F. da Cunha, Daniel A. Polisel, Alexandre A. de Castro, Daiana T. Mancini, Kamil Kuca, Tanos C. C. França
Publikováno v:
Chemico-Biological Interactions. 309:108671
Studies with oximes have been extensively developed to design new reactivators with better efficiency, and greater spectrum of action. In this study, we aimed to analyze the influence of the Carbamoyl group position change in two isomeric oximes, K20