Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Daniel A. Muruve"'
Autor:
Andrew Smith, Vadim Iablokov, Mariafrancesca Mazza, Sonia Guarnerio, Vanna Denti, Mariia Ivanova, Martina Stella, Isabella Piga, Clizia Chinello, Bram Heijs, Peter A. van Veelen, Hallgrimur Benediktsson, Daniel A. Muruve, Fulvio Magni
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-16 (2020)
Introduction: Diabetic nephropathy (DN) and hypertensive nephrosclerosis (HN) represent the most common causes of chronic kidney disease (CKD) and many patients progress to end-stage renal disease. Patients are treated primarily through the managem
Externí odkaz:
https://doaj.org/article/f39314e6838746eda7e2fa511ef0acab
Autor:
Barbora Sporinova, Susanna A. McRae, Daniel A. Muruve, Marvin J. Fritzler, Samih H. Nasr, Alex C. Chin, Hallgrimur Benediktsson
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Anti-glomerular basement membrane (anti-GBM) disease is characterized by circulating IgG glomerular basement membrane antibodies and is clinically expressed as a rapidly progressive crescentic glomerulonephritis (GN), with 30–60
Externí odkaz:
https://doaj.org/article/ab8452f5173749f3ae6f1e9104abf67c
Autor:
Junting Huang, Maria A. Gandini, Lina Chen, Said M’Dahoma, Patrick L. Stemkowski, Hyunjae Chung, Daniel A. Muruve, Gerald W. Zamponi
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108233- (2020)
Summary: The innate immune system responds to infections that give rise to pain. How the innate immune system interacts with the sensory nervous system and contributes to pain is poorly understood. Here we report that hyperactivity of innate immunity
Externí odkaz:
https://doaj.org/article/e135d1776ad946f38a8aae6b3e423cd1
Autor:
Paul Lemire, Susan J. Robertson, Heather Maughan, Ivan Tattoli, Catherine J. Streutker, Jaye M. Platnich, Daniel A. Muruve, Dana J. Philpott, Stephen E. Girardin
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3653-3661 (2017)
NLRP6 is a Nod-like receptor expressed in the intestinal epithelium. Previous studies reported a protective role for NLRP6 against intestinal injury and colitis-associated carcinogenesis via the regulation and establishment of a healthy microbiota. H
Externí odkaz:
https://doaj.org/article/57bb03c1d12c4412a92e8fd9bf11e282
Autor:
Daniel A. Muruve, Michelle C. Mann, Kevin Chapman, Josee F. Wong, Pietro Ravani, Stacey A. Page, Hallgrimur Benediktsson
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Advances in technology and the ability to interrogate disease pathogenesis using systems biology approaches are exploding. As exemplified by the substantial progress in the personalized diagnosis and treatment of cancer, the appli
Externí odkaz:
https://doaj.org/article/ca8b49b7e1d34bccb526c680d9d6fedf
Autor:
Jaye M. Platnich, Hyunjae Chung, Arthur Lau, Christina F. Sandall, Adom Bondzi-Simpson, Huey-Miin Chen, Takanori Komada, Aaron C. Trotman-Grant, Jeremy R. Brandelli, Justin Chun, Paul L. Beck, Dana J. Philpott, Stephen E. Girardin, May Ho, Roger P. Johnson, Justin A. MacDonald, Glen D. Armstrong, Daniel A. Muruve
Publikováno v:
Cell Reports, Vol 25, Iss 6, Pp 1525-1536.e7 (2018)
Summary: The non-canonical caspase-4 and canonical NLRP3 inflammasomes are both activated by intracellular lipopolysaccharide (LPS), but the crosstalk between these two pathways remains unclear. Shiga toxin 2 (Stx2)/LPS complex, from pathogenic enter
Externí odkaz:
https://doaj.org/article/b1fc8d30a7c34e8d876e21e962d781d8
Autor:
Amanda Cunningham, Hallgrimur Benediktsson, Daniel A. Muruve, Ainslie M. Hildebrand, Pietro Ravani
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 5 (2018)
Background: Kidney biopsy is considered the gold standard for diagnosis of renal disease. It is increasingly performed in cases of diagnostic uncertainty, including in patients with coexistent diabetes and hypertension, for which a presumptive clinic
Externí odkaz:
https://doaj.org/article/a02eafbaaa9649b78845ddc6979ca1a8
Publikováno v:
Case Reports in Nephrology, Vol 2018 (2018)
We describe a case of biopsy-proven dabigatran related nephropathy in a patient without underlying IgA nephropathy. To date, dabigatran related nephropathy was only reported in patients with concurrent or undiagnosed IgA nephropathy, suggesting that
Externí odkaz:
https://doaj.org/article/c0ed6cd79766407792fd3d49fa428856
Autor:
Simon A. Hirota, Aito Ueno, Sarah E. Tulk, Helen M. Becker, L. Patrick Schenck, Mireille S. Potentier, Yan Li, Subrata Ghosh, Daniel A. Muruve, Justin A. MacDonald, Paul L. Beck
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
The pathogenesis of Crohn’s disease (CD) involves defects in the innate immune system, impairing responses to microbes. Studies have revealed that mutations NLRP3 are associated with CD. We reported previously that Nlrp3−/− mice were more susce
Externí odkaz:
https://doaj.org/article/672a27eea8bb4adcb334cb3fea64eedc
Publikováno v:
Nature Reviews Nephrology. 19:337-350