Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Daniel A. Linseman"'
Publikováno v:
Advances in Redox Research, Vol 10, Iss , Pp 100097- (2024)
Individuals with a history of mild traumatic brain injury (mTBI) are at an increased risk for neurodegenerative disease, suggesting that intrinsic neuroprotective mechanisms, such as the endogenous antioxidant reservoir, may be depleted long-term aft
Externí odkaz:
https://doaj.org/article/d93b5e1f7f404ad9b56a7b0cc1bec686
Autor:
Daniel A. Linseman, Qun Lu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/0e5d48f5965b40c689db75b2a081051d
Autor:
Allison N. Grossberg, Lilia A. Koza, Aurélie Ledreux, Chad Prusmack, Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Ann-Charlotte Granholm, Daniel A. Linseman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Antibody responses to SARS-CoV-2 may be important biomarkers for assessing the risk for viral transmission. Here the authors present serological antibody profiling results of COVID-19 patients using a new multiplex assay to show distinct kinetics and
Externí odkaz:
https://doaj.org/article/49ad9d0b0b924b0ea4951e73d801de03
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 61 (2022)
Mitochondrial oxidative stress and dysfunction are strongly implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Glutathione (GSH) is an endogenous antioxidant that exists as distinct cytosolic and mitochondrial pools. The status of
Externí odkaz:
https://doaj.org/article/b98f3adccd8f44f486f7c934cbf287a7
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105023- (2020)
Externí odkaz:
https://doaj.org/article/e313d125b308492b92a755494ac2f0d7
Autor:
Aurélie Ledreux, Moira K. Pryhoda, Kim Gorgens, Kevin Shelburne, Anah Gilmore, Daniel A. Linseman, Holly Fleming, Lilia A. Koza, Julie Campbell, Adam Wolff, James P. Kelly, Martin Margittai, Bradley S. Davidson, Ann-Charlotte Granholm
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Concussion or mild traumatic brain injury (mTBI) in athletes can cause persistent symptoms, known as post-concussion syndrome (PCS), and repeated injuries may increase the long-term risk for an athlete to develop neurodegenerative diseases such as ch
Externí odkaz:
https://doaj.org/article/a8863883dac0432f8c57916765073535
Publikováno v:
Neurobiology of Disease, Vol 136, Iss , Pp 104743- (2020)
Rho GTPases play a central role in neuronal survival; however, the antagonistic relationship between Rac and Rho in the regulation of motor neuron survival remains poorly defined. In the current study, we demonstrate that treatment with NSC23766, a s
Externí odkaz:
https://doaj.org/article/164c1d9f09b04e759dd92dc0dee22349
Autor:
Nathan Duval, Whitney A. Sumner, Anna G. Andrianakos, Josie J. Gray, Ron J. Bouchard, Heather M. Wilkins, Daniel A. Linseman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The molecular mechanisms leading to motor neuron death in amyotrophic lateral sclerosis (ALS) are unknown; however, several studies have provided evidence of a central role for intrinsic apoptosis. Bcl-2 homology-3 domain (BH3)-only proteins are pro-
Externí odkaz:
https://doaj.org/article/eaa9ca77aebf44828307083c019709c8
Autor:
Erika K. Ross, Aimee N. Winter, Heather M. Wilkins, Whitney A. Sumner, Nathan Duval, David Patterson, Daniel A. Linseman
Publikováno v:
Antioxidants, Vol 3, Iss 4, Pp 843-865 (2014)
Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis (ALS). Thus, strategies aimed at elevating GSH may yield new therapeutics for ALS. Here, we
Externí odkaz:
https://doaj.org/article/7abfd3314edb4ed99769312747aa3a9a
Publikováno v:
Molecules, Vol 23, Iss 11, p 2956 (2018)
Neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and Parkinson’s disease, are characterized by the progressive loss of neurons in specific regions of the brain and/or spinal cord. Neuronal cell loss ty
Externí odkaz:
https://doaj.org/article/f2273f73c296436b8f97883876428b4f