Výsledky vyhledávání - "Daniel A. Holterman"

Programmed Cell Death 1 (PD-1) and Its Ligand (PD-L1) in Common Cancers and Their Correlation with Molecular Cancer Type

Autor: Daniel D. Von Hoff, Omid Hamid, Peggy Overberg, Anatole Ghazalpour, Gargi D. Basu, Semir Vranic, Nianqing Xiao, Zoran Gatalica, Henry T. Lynch, Todd Maney, Inga Rose, Carrie Snyder, Daniel A. Holterman

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 23:2965-2970

Cancer cells expressing PD-1 ligands (PD-L1/PD-L2) inhibit immune-modulatory T-cell activation facilitating disease progression. Preliminary clinical trials exploring interruption of PD-1/PD-L1 signaling showed benefit in several cancer types. We ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e340053e3e94dda547b3ebccd76e90
https://doi.org/10.1158/1055-9965.epi-14-0654

Zobrazit plný text záznamu

Prostate Tumor Microenvironment Alters Immune Cells and Prevents Long-Term Survival in an Orthotopic Mouse Model Following flt3-Ligand/CD40-Ligand Immunotherapy

Autor: Roy R. Brown, Paul F. Schellhammer, William F. Glass, Nazita Yousefieh, Richard P. Ciavarra, George L. Wright, Patricia Mangiotti, Daniel A. Holterman, Kenneth D. Somers

Publikováno v: Journal of Immunotherapy. 27:13-26

A novel orthotopic metastatic model of mouse prostate cancer was developed using MHC-negative TRAMP-C1P3 (transgenic adenocarcinoma of mouse prostate) cells derived by serial passage of the parental TRAMP-C1 line in mouse prostate glands. TRAMP-C1P3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acecfc47c362b6c0405a34d41fe9def8
https://doi.org/10.1097/00002371-200401000-00002

Zobrazit plný text záznamu

Endoscopic Mapping and Surrogate Markers for Better Surveillance in Barrett Esophagus

Autor: Stanley B. Benjamin, Norio Azumi, Marc E. Lippman, John Hanfelt, Elizabeth A. Montgomery, Glenn M. Eisen, Parul Bhargava, Dan P. Hartmann, Daniel A. Holterman

Publikováno v: American Journal of Clinical Pathology. 114:552-563

Surveillance methods in Barrett esophagus (BE) using light microscopic examination of random biopsy specimens may miss focal dysplasia. In addition, dysplastic foci identified initially may not be relocated subsequently, making chemoprevention studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52eca179db0da0b4fe944620a19b675f
https://doi.org/10.1309/93wg-errb-pn57-c15a

Zobrazit plný text záznamu

The role of NK cell activity in the pathogenesis of poly I:C accelerated and spontaneous diabetes in the diabetes prone BB rat

Autor: Val Abbassi, Norio Azumi, Daniel A. Holterman, Owen C. Blair, John C. Hiserodt, Joseph A. Bellanti, Karen Creswell, Douglas O. Sobel

Publikováno v: Journal of Autoimmunity. 8:843-857

The development of insulin dependent diabetes mellitus (IDDM) and diabetes in the diabetes prone (DP) BB rat animal model of IDDM is thought to be due to an autoimmune process. Natural killer (NK) cells have been implicated but not proven to play a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b80ea7a0e06f98a1f40117eba72168
https://doi.org/10.1016/s0896-8411(95)80021-2

Zobrazit plný text záznamu

Overexpression of alpha-defensin is associated with bladder cancer invasiveness

Autor: Alberto Corica, Jose I. Diaz, Peter F. Blackmore, Antonia Vlahou, John W. Davis, Paul F. Schellhammer, Daniel A. Holterman, Oliver John Semmes

Publikováno v: Urologic oncology. 24(2)

Alpha-defensin (alpha-defensin) has been identified as a potential marker for bladder cancer in urine by surface enhanced laser desorption ionization studies, and confirmed using both immunoabsorption and immunodepletion studies. The objective of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ab0225aa81739e4821d476ca79b71a
https://pubmed.ncbi.nlm.nih.gov/16520271

Zobrazit plný text záznamu

Impact of the tumor microenvironment on host infiltrating cells and the efficacy of flt3-ligand combination immunotherapy evaluated in a treatment model of mouse prostate cancer

Autor: Daniel A. Holterman, Marianne Kulesa Garrett, Richard P. Ciavarra, George L. Wright, William F. Glass, Kenneth D. Somers, Paul F. Schellhammer, Roy R. Brown

Publikováno v: Cancer immunology, immunotherapy : CII. 52(9)

We have previously reported that Fms-like tyrosine kinase-3 ligand (flt3-L) induced tumor stabilization and regression of palpable ectopic prostate tumors (TRAMP-C1). Although some mice remained "tumor free" for several months following termination o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ad6439670e8fb72623540f4b067bcf
https://pubmed.ncbi.nlm.nih.gov/14627125

Zobrazit plný text záznamu

Orthotopic treatment model of prostate cancer and metastasis in the immunocompetent mouse: efficacy of flt3 ligand immunotherapy

Autor: Daniel A. Holterman, Nazita Yousefieh, Paul F. Schellhammer, Richard P. Ciavarra, William F. Glass, Jesse Qian, George L. Wright, Roy R. Brown, Kenneth D. Somers

Publikováno v: International journal of cancer. 107(5)

We established an orthotopic treatment model of prostate cancer to generate reproducible primary and metastatic carcinoma in immunocompetent C57BL/6 mice. Using an in vivo selection scheme of intraprostatic implantation of TRAMP-C1 cells, primary pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8ac8fafa1e888048e6c40d9387f522
https://pubmed.ncbi.nlm.nih.gov/14566827

Zobrazit plný text záznamu

Programmed death 1 (PD-1) lymphocytes and ligand (PD-L1) in colorectal cancer and their relationship to microsatellite instability status

Autor: Kimberly Yeatts, Nianqing Xiao, Zoran Gatalica, Henry T. Lynch, Carrie Snyder, Daniel A. Holterman

Publikováno v: Journal of Clinical Oncology. 32:3625-3625

3625 Background: PD-1 activation by its ligands (PD-L1 and PD-L2) inhibits T-cell activation and plays a role in cancer progression. PD-L1 is widely expressed in many cell types in tumor microenvir...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb81511a9d02ef9c67f1e271957f7e1b
https://doi.org/10.1200/jco.2014.32.15_suppl.3625

Zobrazit plný text záznamu

Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type

Autor: Gargi D. Basu, Daniel A. Holterman, Inga Rose, Daniel D. Von Hoff, Zoran Gatalica, Anatole Ghazalpour, Peggy Overberg, Nianqing Xiao, Omid Hamid

Publikováno v: Journal of Clinical Oncology. 32:e22091-e22091

e22091 Background: PD-1 activation by ligands (PD-L1 and PD-L2) inhibits T-cell activation and facilitates cancer progression. Trials exploring interruption of PD-1/PD-L1 signaling showed benefit i...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d703ada316d0ad30aa8c342a7068b13f
https://doi.org/10.1200/jco.2014.32.15_suppl.e22091

Zobrazit plný text záznamu

Alpha interferon administration paradoxically inhibits the development of diabetes in BB rats

Autor: Karen Creswell, Ji-Won Yoon, Daniel A. Holterman, Douglas O. Sobel

Publikováno v: Life sciences. 62(15)

Alpha-interferon (IFN-alpha) is thought to be important in the pathogenesis of insulin dependent diabetes mellitus (IDDM). However, since potent inducers of IFN-alpha, viruses, have been shown to modulate immune function and autoimmunity, we investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bdbc4d69c91a8fcde33904220a9eca
https://pubmed.ncbi.nlm.nih.gov/9566771

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání