Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Daniel A. Gorelick"'
Autor:
Michael J. Bolt, Jessica Oceguera, Pankaj K. Singh, Kazem Safari, Derek H. Abbott, Kaley A. Neugebauer, Maureen G. Mancini, Daniel A. Gorelick, Fabio Stossi, Michael A. Mancini
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109275- (2024)
Summary: The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and environment can compete with endogenous hormones to alter
Externí odkaz:
https://doaj.org/article/f27ba319ca7e4cc1b5641920f2a19da6
Autor:
Daniel A. Gorelick
Publikováno v:
Biology Open, Vol 13, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/ad4a7931214a4cb3b1c8953585825103
Autor:
Derek A. Abbott, Maureen G. Mancini, Michael J. Bolt, Adam T. Szafran, Kaley A. Neugebauer, Fabio Stossi, Daniel A. Gorelick, Michael A. Mancini
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23119- (2024)
In this study we present an inducible biosensor model for the Estrogen Receptor Beta (ERβ), GFP-ERβ:PRL-HeLa, a single-cell-based high throughput (HT) in vitro assay that allows direct visualization and measurement of GFP-tagged ERβ binding to ER-
Externí odkaz:
https://doaj.org/article/72f160106c83423bac993c7ba9428a4b
Autor:
Daniel A. Gorelick
Publikováno v:
Biology Open, Vol 12, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/76f7b04a215f41ac873ae10acb7b8adc
Publikováno v:
bioRxiv
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that binds DNA and regulates genes in response to halogenated and polycyclic aromatic hydrocarbons. AHR also regulates the development and function of the liver and the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcce94fafb9226b2a7d9099ea9dbae7
https://europepmc.org/articles/PMC10187216/
https://europepmc.org/articles/PMC10187216/
Autor:
Hailey E. Edwards, Daniel A. Gorelick
Publikováno v:
Biochemical Society Transactions. 50:1227-1243
Proteins that contain basic helix-loop-helix (bHLH) and Per-Arnt-Sim motifs (PAS) function as transcription factors. bHLH–PAS proteins exhibit essential and diverse functions throughout the body, from cell specification and differentiation in embry
Publikováno v:
Development. 150
During embryonic development, a subset of cells in the mesoderm germ layer are specified as hemato-vascular progenitor cells, which then differentiate into endothelial cells and hematopoietic stem and progenitor cells. In zebrafish, the transcription
Autor:
Vahid Zadmajid, Daniel A. Gorelick
Androgen actions are classically thought to be mediated by intracellular androgen receptors (AR), but they can also exert non-genomic effects via binding to integral membrane proteins. Although several putative membrane androgen receptors were cloned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4e5dc199539ba729193d4dd622b2eb8
https://doi.org/10.1101/2023.03.20.533512
https://doi.org/10.1101/2023.03.20.533512
Autor:
Shannon N Romano, Hailey E Edwards, Jaclyn Paige Souder, Kevin J Ryan, Xiangqin Cui, Daniel A Gorelick
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007069 (2017)
Estrogens act by binding to estrogen receptors alpha and beta (ERα, ERβ), ligand-dependent transcription factors that play crucial roles in sex differentiation, tumor growth and cardiovascular physiology. Estrogens also activate the G protein-coupl
Externí odkaz:
https://doaj.org/article/b401bda5acf04b77b47ed0b92496f320
Autor:
Amrita Palaria, Arkadi Shwartz, Nadine Budrow, Maija K. Garnaas, Daniel A. Gorelick, Kimberly D. Tremblay, Chia-Cheng Li, Saireudee Chaturantabut, Wolfram Goessling, Trista E. North, Kelli J. Carroll, Kyle A. LaBella, Claire C. Cutting
Publikováno v:
Hepatology
Background and aims During liver development, bipotent progenitor cells differentiate into hepatocytes and biliary epithelial cells to ensure a functional liver required to maintain organismal homeostasis. The developmental cues controlling the diffe