Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Daniel A. Coleman"'
Autor:
Ron Yu, Daniel A. Coleman
Publikováno v:
Contemporary Clinical Trials Communications, Vol 1, Iss C, Pp 22-27 (2015)
Most blinded, late stage, randomized clinical trials package study drug, active or placebo, into drug kits for distribution to investigational sites. Drug kits enable investigators to administer study drug to subjects in a blinded manner without the
Externí odkaz:
https://doaj.org/article/d71bef3d3ba3497c8d3e2a86314af31e
Autor:
Hugo Larocque, Mustafa Atabey Buyukkaya, Carlos Errando-Herranz, Camille Papon, Samuel Harper, Max Tao, Jacques Carolan, Chang-Min Lee, Christopher J. K. Richardson, Gerald L. Leake, Daniel J. Coleman, Michael L. Fanto, Edo Waks, Dirk Englund
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Controlling large-scale many-body quantum systems at the level of single photons and single atomic systems is a central goal in quantum information science and technology. Intensive research and development has propelled foundry-based silico
Externí odkaz:
https://doaj.org/article/3bc3c2026d61461ab72f4aefe3a5db7c
Autor:
Daniel J.L. Coleman, Peter Keane, Paulynn S. Chin, Luke Ames, Sophie Kellaway, Helen Blair, Naeem Khan, James Griffin, Elizabeth Holmes, Alexander Maytum, Sandeep Potluri, Lara Strate, Kinga Koscielniak, Manoj Raghavan, John Bushweller, Olaf Heidenreich, Terry Rabbitts, Peter N. Cockerill, Constanze Bonifer
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109576- (2024)
Summary: AML is characterized by mutations in genes associated with growth regulation such as internal tandem duplications (ITD) in the receptor kinase FLT3. Inhibitors targeting FLT3 (FLT3i) are being used to treat patients with FLT3-ITD+ but most r
Externí odkaz:
https://doaj.org/article/ceddafe74d5942cfbc74b595d7a6e5e4
Autor:
Daniel J.L. Coleman, Peter Keane, Rosario Luque-Martin, Paulynn S. Chin, Helen Blair, Luke Ames, Sophie G. Kellaway, James Griffin, Elizabeth Holmes, Sandeep Potluri, Salam A. Assi, John Bushweller, Olaf Heidenreich, Peter N. Cockerill, Constanze Bonifer
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113568- (2023)
Summary: Acute myeloid leukemia (AML) is a heterogeneous disease caused by different mutations. Previously, we showed that each mutational subtype develops its specific gene regulatory network (GRN) with transcription factors interacting within multi
Externí odkaz:
https://doaj.org/article/72be4bba0590424496380b929459cff5
Autor:
Daniel J. Coleman, Mark Schuerch, Stijn Temmerman, Glenn Guntenspergen, Christopher G. Smith, Matthew L. Kirwan
Publikováno v:
Limnology and Oceanography Letters, Vol 7, Iss 2, Pp 140-149 (2022)
Abstract Tidal marsh survival in the face of sea level rise (SLR) and declining sediment supply often depends on the ability of marshes to build soil vertically. However, numerical models typically predict survival under rates of SLR that far exceed
Externí odkaz:
https://doaj.org/article/370f74670de94c98b42a011c5ca20c98
Autor:
Daniel J. Coleman, David A. Sampson, Archana Sehrawat, Anbarasu Kumaraswamy, Duanchen Sun, Yuzhuo Wang, Jacob Schwartzman, Joshua Urrutia, Ahn R. Lee, Ilsa M. Coleman, Peter S. Nelson, Xuesen Dong, Colm Morrissey, Eva Corey, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 6, Pp 253-262 (2020)
Neuroendocrine prostate cancer (NEPC) is the most virulent form of prostate cancer. Importantly, our recent work examining metastatic biopsy samples demonstrates NEPC is increasing in frequency. In contrast to prostate adenocarcinomas that express a
Externí odkaz:
https://doaj.org/article/d5b944dbbb4c47a8814fa347edf364fc
Autor:
Theodore P. Braun, Joseph Estabrook, Zachary Schonrock, Brittany M. Curtiss, Lucie Darmusey, Jommel Macaraeg, Trevor Enright, Cody Coblentz, Rowan Callahan, William Yashar, Akram Taherinasab, Hisham Mohammed, Daniel J. Coleman, Brian J. Druker, Emek Demir, Theresa A. Lusardi, Julia E. Maxson
Publikováno v:
Leukemia. 37:478-487
Mutations in the gene Additional Sex-Combs Like 1 (ASXL1) are recurrent in myeloid malignancies as well as the pre-malignant condition clonal hematopoiesis, where they are universally associated with poor prognosis. However, the role of ASXL1 in myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9547834293d29eff46db9b2b292473ed
https://doi.org/10.1038/s41375-022-01792-x
https://doi.org/10.1038/s41375-022-01792-x
Autor:
Christopher L. Panuski, Ian Christen, Momchil Minkov, Cole J. Brabec, Sivan Trajtenberg-Mills, Alexander D. Griffiths, Jonathan J. D. McKendry, Gerald L. Leake, Daniel J. Coleman, Cung Tran, Jeffrey St Louis, John Mucci, Cameron Horvath, Jocelyn N. Westwood-Bachman, Stefan F. Preble, Martin D. Dawson, Michael J. Strain, Michael L. Fanto, Dirk R. Englund
Publikováno v:
Nature Photonics. 16:834-842
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63a7f31653c698411bb34a051814a0cb
https://doi.org/10.1038/s41566-022-01086-9
https://doi.org/10.1038/s41566-022-01086-9
Publikováno v:
Estuaries and Coasts. 46:404-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeed085e506a2533ddb3bca8ac21b4ac
https://doi.org/10.1007/s12237-022-01138-x
https://doi.org/10.1007/s12237-022-01138-x
Autor:
Sophie G. Kellaway, Daniel J.L. Coleman, Peter N. Cockerill, Manoj Raghavan, Constanze Bonifer
Publikováno v:
Experimental Hematology. 111:1-12
The transcription factor RUNX1 is essential for correct hematopoietic development; in its absence in the germ line, blood stem cells are not formed. RUNX1 orchestrates dramatic changes in the chromatin landscape at the onset of stem cell formation, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98941789e0c346cae22a05f54767e86
https://doi.org/10.1016/j.exphem.2022.03.009
https://doi.org/10.1016/j.exphem.2022.03.009