Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Daniel A. Colón-Ramos"'
Autor:
Javier Marquina-Solis, Likui Feng, Elke Vandewyer, Isabel Beets, Josh Hawk, Daniel A. Colón-Ramos, Jingfang Yu, Bennett W. Fox, Frank C. Schroeder, Cornelia I. Bargmann
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114042- (2024)
Summary: Pathogenic infection elicits behaviors that promote recovery and survival of the host. After exposure to the pathogenic bacterium Pseudomonas aeruginosa PA14, the nematode Caenorhabditis elegans modifies its sensory preferences to avoid the
Externí odkaz:
https://doaj.org/article/380310b1b4e44327aeb4afe0193dc3b1
Publikováno v:
PLoS Biology, Vol 21, Iss 4 (2023)
Autophagy is essential for cellular homeostasis and function. In neurons, autophagosome biogenesis is temporally and spatially regulated to occur near presynaptic sites, in part via the trafficking of autophagy transmembrane protein ATG-9. The molecu
Externí odkaz:
https://doaj.org/article/0ebfbaa926e142f7827ef25d5ac6c635
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Engineering de novo synapse-like connections between neurons could enhance our understanding of neuronal circuits and how they generate behaviour. The authors present a two-component system that creates synthetic neuromodulatory connections to manipu
Externí odkaz:
https://doaj.org/article/011bbc5d4fc94de3b2244cd6f41fc519
Autor:
Titas Sengupta, Noelle L Koonce, Nabor Vázquez-Martínez, Mark W Moyle, Leighton H Duncan, Sarah E Emerson, Xiaofei Han, Lin Shao, Yicong Wu, Anthony Santella, Li Fan, Zhirong Bao, William A Mohler, Hari Shroff, Daniel A Colón-Ramos
Publikováno v:
eLife, Vol 10 (2021)
During development, neurites and synapses segregate into specific neighborhoods or layers within nerve bundles. The developmental programs guiding placement of neurites in specific layers, and hence their incorporation into specific circuits, are not
Externí odkaz:
https://doaj.org/article/e76231349ddb4528bf5399da88172428
Autor:
Kristopher M Barnes, Li Fan, Mark W Moyle, Christopher A Brittin, Yichi Xu, Daniel A Colón-Ramos, Anthony Santella, Zhirong Bao
Publikováno v:
eLife, Vol 9 (2020)
The internalization of the central nervous system, termed neurulation in vertebrates, is a critical step in embryogenesis. Open questions remain regarding how force propels coordinated tissue movement during the process, and little is known as to how
Externí odkaz:
https://doaj.org/article/9b221a85d38d45bdaa080861aff0ba7f
Autor:
Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Mengqing Wang, Laura Manning, Xiaohua Dong, Yanjun Shi, Xumin Zhang, Zhiyong Shao, Daniel A Colón-Ramos
Publikováno v:
eLife, Vol 9 (2020)
Synaptic positions underlie precise circuit connectivity. Synaptic positions can be established during embryogenesis and sustained during growth. The mechanisms that sustain synaptic specificity during allometric growth are largely unknown. We perfor
Externí odkaz:
https://doaj.org/article/2d920636b8eb4f62a6b5ee3b28cc6cfe
Autor:
Yicong Wu, Ryan Christensen, Arpita Upadhyaya, Jiamin Liu, Yilun Sun, Akshay Patel, Titas Sengupta, Yves Pommier, Hari Shroff, Ivan Rey-Suarez, Jonathan S. Daniels, Christian A. Combs, Daniel A. Colón-Ramos, Lingyu Bao, Jiji Chen, Melissa Glidewell, Junhui Sun, Xufeng Wu, Robert S. Fischer, Xiaofei Han, Corey Smith, Leighton H. Duncan, Yun-Bo Shi, Sougata Roy, Yijun Su, Elizabeth Murphy, Patrick J. La Riviere
Publikováno v:
Nature. 600:279-284
Confocal microscopy1 remains a major workhorse in biomedical optical microscopy owing to its reliability and flexibility in imaging various samples, but suffers from substantial point spread function anisotropy, diffraction-limited resolution, depth-
Autor:
Zhao Xuan, Laura Manning, Jessica Nelson, Janet E Richmond, Daniel A Colón-Ramos, Kang Shen, Peri T Kurshan
Publikováno v:
eLife, Vol 6 (2017)
Active zone proteins cluster synaptic vesicles at presynaptic terminals and coordinate their release. In forward genetic screens, we isolated a novel Caenorhabditis elegans active zone gene, clarinet (cla-1). cla-1 mutants exhibit defects in synaptic
Externí odkaz:
https://doaj.org/article/631e3dc98cd347b68b384be1f62e5d8d
Autor:
Milind Singh, Daniel A. Colón-Ramos, Louise Jawerth, Zhao Xuan, Dirk R. Albrecht, Hee Soo Kim, Shavanie Prashad, SoRi Jang, Avinash Patel, Ian Gonzalez, Anthony A. Hyman, Ross C. Lagoy
Publikováno v:
Biophysical Journal. 120:1170-1186
Although much is known about the biochemical regulation of glycolytic enzymes, less is understood about how they are organized inside cells. We systematically examine the dynamic subcellular localization of glycolytic protein phosphofructokinase-1/PF
Autor:
Guy Wolf, Alex Gonopolskiy, Kevin R. Moon, Min Guo, Yicong Wu, Ryan Christensen, Anthony Santella, Mark W. Moyle, Zhirong Bao, Abhishek Kumar, Daniel A. Colón-Ramos, Lin Shao, Manik Kuchroo, William A. Mohler, Kristopher M. Barnes, Titas Sengupta, Smita Krishnaswamy, Leighton H. Duncan, Hari Shroff
Publikováno v:
Nature
SummaryNeuropil is a fundamental form of tissue organization within brains1. In neuropils, densely packed neurons synaptically interconnect into precise circuit architecture2,3, yet the structural and developmental principles governing nanoscale prec