Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel A. Bórquez"'
A Brain Anti-Senescence Transcriptional Program Triggered by Hypothalamic-Derived Exosomal microRNAs
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5467 (2024)
In contrast to the hypothesis that aging results from cell-autonomous deterioration processes, the programmed longevity theory proposes that aging arises from a partial inactivation of a “longevity program” aimed at maintaining youthfulness in or
Externí odkaz:
https://doaj.org/article/e013e7badc3c41eda7b7c279f70eb8b1
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1807 (2022)
Selective regional iron accumulation is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. The underlying mechanisms of neuronal iron dyshomeostasis have been studied, mainly in a gene-by-gene
Externí odkaz:
https://doaj.org/article/88154fda5feb418081958e0ba9cdc27b
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 61 (2021)
Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationshi
Externí odkaz:
https://doaj.org/article/467c9b1c84564a83a6ef49672c3f7a9b
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2012 (2012)
Since its proposal in 1994, the amyloid cascade hypothesis has prevailed as the mainstream research subject on the molecular mechanisms leading to the Alzheimer's disease (AD). Most of the field had been historically based on the role of the differen
Externí odkaz:
https://doaj.org/article/f52fb8e039c1470b91a0b0357f849ed0
Autor:
Cecilia Conde, Cristopher Villablanca, Mitsunori Fukuda, Daniel A. Bórquez, Yuta Homma, Christian Gonzalez-Billault, Felipe Bodaleo, Pamela J. Urrutia, Victoria Rozés-Salvador
Publikováno v:
J Neurosci
The acquisition of neuronal polarity is a complex molecular process that depends on changes in cytoskeletal dynamics and directed membrane traffic, regulated by the Rho and Rab families of small GTPases, respectively. However, during axon specificati
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 61, p 61 (2021)
Antioxidants, Vol 10, Iss 61, p 61 (2021)
Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Iron and inflammation are intertwined in a bidirectional relationshi
Autor:
Victoria Rozés-Salvador, Daniel A. Bórquez, Cecilia Conde, Cristopher Villablanca, Mitsunori Fukuda, Pamela J. Urrutia, Christian Gonzalez-Billault, Felipe Bodaleo
The acquisition of neuronal polarity is a complex molecular process that involves several different cellular mechanisms that need to be finely coordinated to define the somatodendritic and axonal compartments. Amongst such mechanisms, cytoskeleton an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc77334473ffad658cd164389ed3520
https://doi.org/10.1101/2019.12.16.876011
https://doi.org/10.1101/2019.12.16.876011
Publikováno v:
Bioinformatics-Updated Features and Applications
Protein phosphorylation, catalyzed by protein kinases, is the main posttranslational modification in eukaryotes, regulating essential aspects of cellular function. Using mass spectrometry techniques, a profound knowledge has been achieved in the loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435f3df77f56481408449897783c88cc
http://www.intechopen.com/articles/show/title/bioinformatics-approaches-for-predicting-kinase-substrate-relationships
http://www.intechopen.com/articles/show/title/bioinformatics-approaches-for-predicting-kinase-substrate-relationships
Autor:
Christian Gonzalez-Billault, Daniel A. Bórquez, Brigitte van Zundert, Marco T. Núñez, Pamela J. Urrutia, Carlos Wilson
Publikováno v:
Journal of Neurochemistry
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The generation of abnormally high levels of reactive oxygen species (ROS) is linked to cellular dysfunction, including neuronal toxicity and neurodegeneration. However, physiological ROS production modulates redox-sensitive roles of several molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af10e7c7d28c4e58f5eb9b97e5985e7
Wiley Online Library
Wiley Online Library
Publikováno v:
BIOLOGICAL RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Biological Research v.44 n.1 2011
SciELO Chile
Biological Research, Vol 44, Iss 1, Pp 35-41 (2011)
Biological Research, Volume: 44, Issue: 1, Pages: 35-41, Published: 2011
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Biological Research v.44 n.1 2011
SciELO Chile
Biological Research, Vol 44, Iss 1, Pp 35-41 (2011)
Biological Research, Volume: 44, Issue: 1, Pages: 35-41, Published: 2011
Epithelial and neuronal cells are highly asymmetric, with discrete regions responsible for different roles that underlie the generation of specifi c compartments within cells that are distinct in biochemical composition, structure, and morphology th