Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniel B. Patience"'
Autor:
Paria Coliaie, Rajan R. Bhawnani, Rabia Ali, Manish S. Kelkar, Akshay Korde, Marianne Langston, Chengxiang Liu, Neda Nazemifard, Daniel B. Patience, Tamar Rosenbaum, Dimitri Skliar, Nandkishor K. Nere, Meenesh R. Singh
Publikováno v:
ACS Omega, Vol 8, Iss 44, Pp 41502-41511 (2023)
Externí odkaz:
https://doaj.org/article/882c1ebff85a4a24a633c6fac754f6d2
Publikováno v:
Organic Process Research & Development. 26:2377-2391
Autor:
Frederick G. Vogt, Yemane W. Andemichael, Sonja Sharpe, Lori Wernersbach, Susan V. Downing, Daniel B. Patience, Julie Tsui, Peng Liu, Lynette M. Oh, Wenning Dai, Jacalyn S. Clawson, Leon Zhou, James T. Wertman, Alan J. Freyer, Joseph Sisko, Jun Chen, Jun Wang, Edward C. Webb, Diederich Ann M
Publikováno v:
Organic Process Research & Development. 13:729-738
A scalable synthesis of a novel pleuromutilin-based antibiotic is reported. The synthesis features the scale-up of an interesting skeletal rearrangement of the pleuromutilin core and isolation of a highly purified product despite starting with relati
Autor:
Alan D. Jones, Joseph Sisko, Tran N. Pham, Matthew N. Johnson, Jeffrey Brum, Wenning Dai, Daniel B. Patience, Jacalyn S. Clawson, Royston C. P. Copley, Sonja Sharpe, Frederick G. Vogt
Publikováno v:
Crystal Growth & Design. 8:4120-4131
An unusual pharmaceutical solid containing a pleuromutilin derivative, succinic acid and water is studied with a combination of physiochemical methods. The parent pleuromutilin derivative creates a host structure that contains large channels, which a
Autor:
Daniel B. Patience, Lynette M. Oh, Huan Wang, Joseph Sisko, P. Grant Spoors, Robert E. Herrmann, Susan Shilcrat
Publikováno v:
Organic Process Research & Development. 11:1032-1042
A scalable synthesis of GSK183390A, a PPAR α/γ agonist, is described. This synthesis is highlighted by (1) a regioselective formal 1,3-dipolar cycloaddition reaction between an enamine and a nitrile imine dipole to form a 1,3,5-trisubstituted pyraz
Publikováno v:
IEEE Control Systems. 26:70-80
The objective of every industrial crystallization process is to create crystals that meet specifications on size, shape, composition, and internal structure. This objective is achieved using a variety of methods and equipment configurations depending
Publikováno v:
Chemical Engineering Science. 60:2627-2641
The stochastic chemical kinetics approach provides one method of formulating the stochastic crystallization population balance equation (PBE). In this formulation, crystal nucleation and growth are modelled as sequential additions of solubilized ions
Publikováno v:
Organic Process Research & Development. 8:609-615
A cooling profile for a seeded pharmaceutical crystallization designed to achieve a desired mean crystal size is found by minimizing the batch operating time subject to a crystallization model. In many systems, optimizing a characteristic of the prod
Publikováno v:
AIChE Journal. 47:2441-2451
Crystallization kinetics of para-xylene in batch pilot-scale scraped-surface crystallizers were determined for commercial crystallization of a xylene mixture currently produced in Amoco plants. Dynamic mass and energy balances, coupled with the dynam
Autor:
Daniel B. Patience, James B. Rawlings
Publikováno v:
AIChE Journal. 47:2125-2130
We present a simple technique that can identify suitable data from a noisy signal produced on-line by commercially available image-analysis software. A controller successfully uses this signal to regulate the flow rate of a habit modifier stream to m