Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Daniel Čapek"'
Autor:
Paul Knabl, Alexandra Schauer, Autumn P Pomreinke, Bob Zimmermann, Katherine W Rogers, Daniel Čapek, Patrick Müller, Grigory Genikhovich
Publikováno v:
eLife, Vol 13 (2024)
BMP signaling has a conserved function in patterning the dorsal-ventral body axis in Bilateria and the directive axis in anthozoan cnidarians. So far, cnidarian studies have focused on the role of different BMP signaling network components in regulat
Externí odkaz:
https://doaj.org/article/8fc335e306734781bdc9897f76db1b6a
Autor:
Timo Kuhn, Amit N. Landge, David Mörsdorf, Jonas Coßmann, Johanna Gerstenecker, Daniel Čapek, Patrick Müller, J. Christof M. Gebhardt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Multiple models have been proposed for how diffusion is regulated to shape morphogen gradients. Here they use single molecule tracking of an activator-inhibitor signaling pair in a developing tissue to show how effective diffusivity is modulated in t
Externí odkaz:
https://doaj.org/article/a2d2dc60ed4845979a91e443ecec2e62
Autor:
Hannes Preiß, Anna C Kögler, David Mörsdorf, Daniel Čapek, Gary H Soh, Katherine W Rogers, Hernán Morales-Navarrete, María Almuedo-Castillo, Patrick Müller
Publikováno v:
eLife, Vol 11 (2022)
During vertebrate embryogenesis, the germ layers are patterned by secreted Nodal signals. In the classical model, Nodals elicit signaling by binding to a complex comprising Type I/II Activin receptors (Acvr) and the co-receptor Tdgf1. However, it is
Externí odkaz:
https://doaj.org/article/40338d055d964c1387c3990bfbc5eefa
Autor:
Daniel Čapek, Michael Smutny, Alexandra-Madelaine Tichy, Maurizio Morri, Harald Janovjak, Carl-Philipp Heisenberg
Publikováno v:
eLife, Vol 8 (2019)
Non-canonical Wnt signaling plays a central role for coordinated cell polarization and directed migration in metazoan development. While spatiotemporally restricted activation of non-canonical Wnt-signaling drives cell polarization in epithelial tiss
Externí odkaz:
https://doaj.org/article/55294d5d287f45b0901b9d4d1dc4b696
Autor:
Keisuke Sako, Saurabh J. Pradhan, Vanessa Barone, Álvaro Inglés-Prieto, Patrick Müller, Verena Ruprecht, Daniel Čapek, Sanjeev Galande, Harald Janovjak, Carl-Philipp Heisenberg
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 866-877 (2016)
During metazoan development, the temporal pattern of morphogen signaling is critical for organizing cell fates in space and time. Yet, tools for temporally controlling morphogen signaling within the embryo are still scarce. Here, we developed a photo
Externí odkaz:
https://doaj.org/article/844fc9840afe40f88c9c4914fbd0d71c
Autor:
Daniel Čapek, Matvey Safroshkin, Hernán Morales-Navarrete, Nikan Toulany, Grigory Arutyunov, Anica Kurzbach, Johanna Bihler, Julia Hagauer, Sebastian Kick, Felicity Jones, Ben Jordan, Patrick Müller
Evolutionarily conserved signaling pathways are essential for early embryogenesis, and reducing or abolishing their activity leads to characteristic developmental defects. Classification of phenotypic defects can identify the underlying signaling mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c88842a5be29135e69bd81724178dbe
Autor:
David Mörsdorf, Anna C Kögler, Hannes Preiß, Daniel Čapek, Gary H Soh, Katherine W Rogers, Hernán Morales-Navarrete, María Almuedo-Castillo, Patrick Müller
During vertebrate embryogenesis, the germ layers are patterned by secreted Nodal signals. In the classical model, Nodals elicit signaling by binding to a complex comprising Type I/II Activin receptors (Acvr) and the co-receptor Tdgf1. However, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866b1fcb54cc0d405d5660c7631ac2d3
http://hdl.handle.net/10261/305738
http://hdl.handle.net/10261/305738
Autor:
David Mörsdorf, Anna C Kögler, Hannes Preiß, Daniel Čapek, Gary H Soh, Katherine W Rogers, Hernán Morales-Navarrete, María Almuedo-Castillo, Patrick Müller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34639f536f3cb225c87a9ce4292bc1c0
https://doi.org/10.7554/elife.66397.sa2
https://doi.org/10.7554/elife.66397.sa2
Publikováno v:
BIOspektrum
The central question in developmental biology is how an embryo self-organizes from a ball of cells into a structured animal. We use experimental and theoretical approaches to study how the activity of a small number of signaling molecules is spatiote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4030d17c946ecc966dd8976c98cc2a5
Autor:
Patrick Müller, Daniel Čapek
Publikováno v:
Development
In order to contribute to the appropriate tissues during development, cells need to know their position within the embryo. This positional information is conveyed by gradients of signaling molecules, termed morphogens, that are produced in specific r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6b3f7dd83a5fcaeffcce0efffc0c1b
https://doi.org/10.1242/dev.177709
https://doi.org/10.1242/dev.177709