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Castration is a prerequisite for the inhibitory effect of metronomic chemotherapy on the growth of experimental castration-resistant prostate cancer

Autor: Daniel Åhs, Josefin Olausson, Jan-Erik Damber, Ingela Franck Lissbrant, Karin Welén, Åsa Jellvert

Publikováno v: Acta oncologica (Stockholm, Sweden). 57(7)

Low-dose metronomic chemotherapy (LDMC) is an alternative for treatment of patients with late-stage prostate cancer (PC) not susceptible to regular chemotherapy due to its severe side effects. The exact working mechanisms of LDMC have not been establ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ff33cf6c876051e818e2b6d329f178
https://pubmed.ncbi.nlm.nih.gov/29299975

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Circulating tumor cells mirror bone metastatic phenotype in prostate cancer

Autor: Andreas Josefsson, Karin Welén, Jan-Erik Damber, Helena Brisby, Karin Larsson, Marianne Månsson, Jens Björkman, Daniel Åhs, Eva Rohlova

Publikováno v: Oncotarget

Circulating tumor cells (CTCs) are promising biomarkers in prostate cancer (PC) because they derive from primary tumor and metastatic tissues. In this study, we used quantitative real-time PCR (qPCR) to compare the expression profiles of 41 PC-relate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e36d5df38ceec4814fbc23999857d08
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-159988

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Abstract B071: Circulating tumor cells as liquid biopsies of skeletal metastases from prostate cancer

Autor: Daniel Åhs, Helena Brisby, Karin Larsson, Jan-Erik Damber, Andreas Josefsson, Karin Welén

Publikováno v: Cancer Research. 78:B071-B071

Background: Circulating tumor cells (CTC) are promising biomarkers in advanced prostate cancer. Since they are seeded from metastases, they may also serve as liquid biopsies for skeletal metastases that are difficult to sample. The aim of the present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5d963497774349e9d7a45cafc7f32db
https://doi.org/10.1158/1538-7445.prca2017-b071

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Abstract B082: Osteolytic and osteoblastic prostate cancer cells remotely trigger different responses in the bone marrow niche

Autor: Jan-Erik Damber, Andreas Josefsson, Karin Welén, Daniel Åhs

Publikováno v: Cancer Research. 78:B082-B082

Background: Prostate cancer (PC) mainly metastasizes to the bone, which is why the bone marrow is an organ of interest when investigating mechanisms for metastasis. Earlier studies have shown that primary tumors have the capability to affect target o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7aea064555513ced25757c1aef4c04aa
https://doi.org/10.1158/1538-7445.prca2017-b082

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