Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Daniel, Zwilling"'
Autor:
Hanson Ho, Matt De Both, Ashley Siniard, Sasha Sharma, James H. Notwell, Michelle Wallace, Dino P. Leone, Amy Nguyen, Eric Zhao, Hannah Lee, Daniel Zwilling, Kimberly R. Thompson, Steven P. Braithwaite, Matthew Huentelman, Thomas Portmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Recent advances in single-cell technologies are paving the way to a comprehensive understanding of the cellular complexity in the brain. Protocols for single-cell transcriptomics combine a variety of sophisticated methods for the purpose of isolating
Externí odkaz:
https://doaj.org/article/b03140c1e93d4a4cabe3a75dd3633aa5
Autor:
Sergi Ferré, Jordi Bonaventura, Wendy Zhu, Candice Hatcher-Solis, Jaume Taura, César Quiroz, Ning-Sheng Cai, Estefanía Moreno, Verónica Casadó-Anguera, Alexxai V. Kravitz, Kimberly R. Thompson, Dardo G. Tomasi, Gemma Navarro, Arnau Cordomí, Leonardo Pardo, Carme Lluís, Carmen W. Dessauer, Nora D. Volkow, Vicent Casadó, Francisco Ciruela, Diomedes E. Logothetis, Daniel Zwilling
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The central adenosine system and adenosine receptors play a fundamental role in the modulation of dopaminergic neurotransmission. This is mostly achieved by the strategic co-localization of different adenosine and dopamine receptor subtypes in the tw
Externí odkaz:
https://doaj.org/article/38b2b15a7fb34720abd17bdefcd1f850
Autor:
Yaisa Andrews-Zwilling, Anna K Gillespie, Alexxai V Kravitz, Alexandra B Nelson, Nino Devidze, Iris Lo, Seo Yeon Yoon, Nga Bien-Ly, Karen Ring, Daniel Zwilling, Gregory B Potter, John L R Rubenstein, Anatol C Kreitzer, Yadong Huang
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40555 (2012)
Although extensive research has demonstrated the importance of excitatory granule neurons in the dentate gyrus of the hippocampus in normal learning and memory and in the pathogenesis of amnesia in Alzheimer's disease (AD), the role of hilar GABAergi
Externí odkaz:
https://doaj.org/article/1f169e12eed84a99bcdef4bcb3aeb143
Autor:
Steven M, Grauer, Raul, Sanoja, Dominic, Poulin, Harunor, Rashid, Nina, Jochnowitz, Michael, Calhoun, Daniel, Zwilling, Geoffrey B, Varty, Thomas W, Rosahl, Hamid, Meziane, Christopher, Mittlelhaeuser, Robert, Mazzola, John, Morrow, Sean M, Smith, Darrell, Henze, Jacob, Marcus
Publikováno v:
Brain research. 1737
Analgesic properties of orthosteric agonists of the muscarinic M
Autor:
John A. Morrow, Raul Sanoja, Jacob Marcus, Daniel Zwilling, Darrell A. Henze, Nina Jochnowitz, Christopher Mittlelhaeuser, Robert Mazzola, Michael Calhoun, Hamid Meziane, Harunor Rashid, Dominic Poulin, Sean M. Smith, Thomas W. Rosahl, Geoffrey B. Varty, Steven M. Grauer
Publikováno v:
Brain Research. 1737:146814
Analgesic properties of orthosteric agonists of the muscarinic M4 receptor subtype have been documented in literature reports, with evidence from pharmacological and in vivo receptor knock out (KO) studies. Constitutive M4 receptor KO mice demonstrat
Autor:
Sergi, Ferré, Jordi, Bonaventura, Wendy, Zhu, Candice, Hatcher-Solis, Jaume, Taura, César, Quiroz, Ning-Sheng, Cai, Estefanía, Moreno, Verónica, Casadó-Anguera, Alexxai V, Kravitz, Kimberly R, Thompson, Dardo G, Tomasi, Gemma, Navarro, Arnau, Cordomí, Leonardo, Pardo, Carme, Lluís, Carmen W, Dessauer, Nora D, Volkow, Vicent, Casadó, Francisco, Ciruela, Diomedes E, Logothetis, Daniel, Zwilling
Publikováno v:
Frontiers in Pharmacology
The central adenosine system and adenosine receptors play a fundamental role in the modulation of dopaminergic neurotransmission. This is mostly achieved by the strategic co-localization of different adenosine and dopamine receptor subtypes in the tw
Autor:
Paul J. Muchowski, Yadong Huang, Grit Laue, Eliezer Masliah, Jongmin Lee, Arash Rassoulpour, Korrapati V. Sathyasaikumar, Flaviano Giorgini, Shao-Yi Huang, Jamie Y. Louie, Gunnar Flik, Hui-Qiu Wu, Tiffany Wu, Yaisa Andrews-Zwilling, Jennifer Truong, Robert Schwarcz, Christina Patrick, Joseph M. Muchowski, Saliha Moussaoui, Kimberly Scearce-Levie, Eric Hsieh, Daniel Zwilling, Anthony Adame, Francesca M. Notarangelo, Paolo Guidetti
Publikováno v:
Cell. 145(6):863-874
SummaryMetabolites in the kynurenine pathway, generated by tryptophan degradation, are thought to play an important role in neurodegenerative disorders, including Alzheimer's and Huntington's diseases. In these disorders, glutamate receptor-mediated
Autor:
Daniel Zwilling, Yadong Huang, Seo Yeon Yoon, Tonya Xue Yan, Qin Xu, Ligong Chen, Yaisa Andrews-Zwilling, Aubrey Bernardo, Nga Bien-Ly, Gang Li
Publikováno v:
The Journal of Neuroscience. 30:13707-13717
Apolipoprotein E4 (apoE4) is the major genetic risk factor for Alzheimer's disease. However, the underlying mechanisms are unclear. We found that female apoE4 knock-in (KI) mice had an age-dependent decrease in hilar GABAergic interneurons that corre
Autor:
Soyon Hong, Robert Schwarcz, Jennifer L. Wacker, Li-Chun L. Tsai, Flaviano Giorgini, Christine S. Cheah, Daniel Zwilling, Paolo Guidetti, Paul J. Muchowski, Wanda Kwan, Thomas Möller
Publikováno v:
Journal of Biological Chemistry. 283:7390-7400
The kynurenine pathway of tryptophan degradation is hypothesized to play an important role in Huntington disease, a neurodegenerative disorder caused by a polyglutamine expansion in the protein huntingtin. Neurotoxic metabolites of the kynurenine pat
Autor:
Dorothea Brandhorst, Silvio O. Rizzoli, Reinhard Jahn, Thorsten Lang, Daniel Zwilling, Undine Lippert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Membrane fusion in the secretory pathway is mediated by soluble N -ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins. Different fusion steps are thought to be effected by independent sets of SNAREs, but it is unclear whether specif